Quality of life evaluation in acute leukemia patients receiving induction chemotherapy

Abstract

Background: Over the past decades, special attention has been paid to study of quality of life (QoL) indicators in hematological patients receiving chemotherapy (CT). Nowadays QoL is conceptually viewed as an important complement to traditional objective evaluation measures. Aim. To assess QoL in patients with acute leukemia (AL) depending on the presence of concomitant ischemic heart disease (1HD) during the induction CT. Methods: Our study involved 83 patients with newly diagnosed AL, of which 19 were lymphoblastic, 64-myeloid leukemia, aged 16-72,43 (51.8%) men, 40 (48.2%) women, according to ECOG l-II. Patients received standard induction CT. According to concomitant IFID patients were divided into groups: I (n — 47) - AL without cardio­ logical diseases; II (n = 36) - AL with concomitant IHD. Patients were evaluated using SF-36 questionnaire to calculate physical and mental health components before treatment and after 2 induction courses of CT reaching remission.