Вплив реабілітаційних заходів на абсолютну і відносну кількість основних популяцій імунокомпетентних клітин периферичної крові дітей 7-17 років із сколіозом

Abstract

У роботі представлено вплив реабілітаційних заходів на абсолютну і відносну кількість основних популяцій імунокомпетентних клітин периферичної крові дітей 7-17 років із сколіозом. Встановили, що проведені фізичні реабілітаційні заходи у хлопчиків та дівчат позитивно впливають на абсолютну відносну кількість основних популяцій ІКК периферичної крові дітей із сколіозом, підвищуючи відносну кількість моноцитів (макрофагів), еозинофільних гранулоцитів та понижуючи відносну кількість паличкоядерних нейтрофільних гранулоцитів.

В работе представлено влияние реабилитационных мероприятий на абсолютное и относительное количество основных популяций иммунокомпетентных клеток периферической крови детей 7-17 лет со сколиозом. Установили, что проведенные физические реабилитационные мероприятия у ребят положительно влияют на абсолютное относительное количество основных популяций ИКК периферической крови детей со сколиозом, повышая относительное количество моноцитов (макрофагов), эозинофилов и снижая относительное количество палочкоядерных нейтрофилов.

Established changes in adaptive tension, cellular reactivity of the organism, reactive response of neutrophilic granulocytes and general immunological reactivity of the organism in children aged 7-17 years suffering from scoliosis, require correction. Since the changes in the parameters characterizing the adaptation processes, the cellular reactivity of the organism, the reactive response of the neutrophilic granulocytes of the peripheral blood and the overall immune reactivity correspond to the first degree of immune disorders, therefore, they are not prescribed for the correction of specific drugs, but only carry out constant monitoring of these indicators and use psychotherapeutic and physical rehab measures to improve motor activity and the quality of life of children with special needs. The aim of the study. To study the effect of rehabilitation measures on the absolute and relative number of major populations of immunocompetent peripheral blood cells in children aged 7-17 years with scoliosis. The object and methods of research. The bases for the study were: a specialized general-education sanatorium boarding school for children with scoliosis in the city of Alekseyevo-Druzhkovka, Donetsk region. The study was conducted in children aged 7-17 years with scoliosis (26 boys and 27 girls). The results of the study of the effect of developed rehabilitation physical measures on the absolute and relative number of major IQC populations in peripheral blood in children aged 7-17 years contribute to an increase in the relative amount of monocytes at 7.17% (P <0.05), which have a high ability to phagocytosis, recognition antigens, synthesis to immune regulatory monoclines (cytokines), neutralization of elements of tissue detritus and increases immunological protection of an organism. There is a slight tendency to decrease (normalize) the absolute and relative number of granulocytes and agranulocytes; lymphocytes – the main figure of adaptive immunity; neutrophilic granulocytes (their mature forms – segmental neutrophilic leukocytes). As a result of our physical rehabilitation measures developed by us, boys aged 7-17 years with scoliosis increase the relative number of eosinophilic granulocytes by 27.07% (P <0.05) and the tendency to increase the absolute amount by 6.63% and the relative amount of 3 , 26% of agranulocytes at the expense of an increase of 8.28% of the absolute amount and the relative amount of 4.81% of the lymphocytes. The results of the study of the absolute and relative numbers of major populations of peripheral blood-brain ICHs in girls with scoliosis showed that the use of developed physical rehabilitation measures positively affects the normalization of the disturbed parameters of absolute and relative numbers of major IQC populations of peripheral blood in girls. At the same time, the relative number of monocytes, eosinophilic granulocytes increases by 22.46% and the relative number of young forms of neutrophil granulocytes (sticks) is reduced by 12.81% by 18.60%. Conclusions. The use of physical rehabilitation measures developed by us in boys and girls of school age (7-17 years of age) is positively reflected on the normalization of the indices of absolute and relative numbers of major populations of immunocompetent peripheral blood cells of children with scoliosis. The tendency towards normalization of absolute and relative indices of populations in peripheral blood of girls with scoliosis leads to a decrease (ρ<0.05) of the rate of erythrocyte sedimentation. Prospects for further research. The basic scientific provisions obtained and given in the article are the basis for studying the measures and means aimed at improving the adaptive processes of the cellular and immune reactivity of the organism in children aged 7-10, 11-14, 15-17 years with a pathology of vision.