Проблеми екології та медицини, 2020, Том 24, № 5-6
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Документ Patterns in Google Trends terms reporting rhinitis and alternaria season in Ukraine(Полтавський державний медичний університет, 2020) Kaidashev, I.; Morokhovets, H.; Rodinkova, V.; Bilous, O.; DuBuske, L. M.; Bousquet, J; Кайдашев, Ігор Петрович; Мороховець, Галина ЮріївнаThis article presents a literary review on the issue of using the innovative Web-based surveillance tools provided by Google Trends (GT) in order to determine the precise onset of the mold spore season. Mold allergy is a considerable trigger for the development of widespread respiratory disorders – allergic rhinitis and asthma, chronic obstructive pul-monary diseases, etc.The study aimed to examine the seasonality of GT queries in Ukraine with Alternaria pollen counts. Spores of the genus Alternaria belong to one of the most prevailing constituents of the air in all regions of the world. They form infectious inoculum of numerous plant species as well as severe inhaled allergies. A precise definition of the mold spore season onset is crucial to confirm the mold allergy diagnosis and to develop personalized treatment for patients with allergic rhinitis and asthma. The most comprehensive approach is the development of a pan-European sen-tinel network, which combines all these strategies. GT may be a useful tool in the differentiation of the mold spore sea-sons, especially when they overlap as in the case ofAmbrosia. Four terms “running nose”, “tears”, “dyspnea”, and “cough” (in Cyrillic equivalents) are required in Ukraine to account for Alternaria spore exposure. The combination of GT tools with spore counts may be used in large-scale epidemiological studies. The development of a pan-European sentinel network for allergic diseases has raised the problem of translating the Google search terms into different European lan-guages. GT analysis is a tool to improve and tailor our communication with patients and the general public along with building our sentinel network languages. Our data can be used as a successful tool for allergy patients to prevent or minimize exposure during the mold spore season. У статті представлено літературний огляд проблеми використання інноваційних інструментів веб-спостереження, зокрема Google Trends (GT), з метою визначення точного початку сезону спор цвілі. Алергія на цвіль є значним пусковим механізмом розвитку поширених респіраторних розладів –алергічного риніту та астми, хронічного обструктивного захворювання легень тощо. Метою дослідження було вивчення сезонності запитів GT в Україні з кількістю спор Alternaria. Спори роду Alternaria – найпоширеніша складова повітря у всіх регіонах світу, що утворюють інфекційний посівний матеріал численних видів рослин, а також спричиняють важку інгаляційну алергію. Точне визначення настання сезону спор цвілі є вирішальним для підтвердження діагнозу алергії на цвіль та розробки персоналізованого лікування для пацієнтів з алергічним ринітом та астмою. Найбільш комплексним підходом є розвиток загальноєвропейської мережі моніторингу, яка поєднує всі ці стратегії. GT може бути корисним інструментом для диференціації сезонів спор Alternaria, особливо коли вони співпадають з сезоном цвітіння амброзії. Чотири терміни "нежить", "сльози", "задишка" та "кашель" (кирилицею) слід використовувати в Україні для пояснення впливу спор Alternaria. Поєднання запитів GT з кількістю спор може бути використано в масштабних епідеміологічних дослідженнях. Розвиток загальноєвропейської сигнальної мережі моніторингу алергічних захворювань зумовлює проблему перекладу пошукових термінів різними європейськими мовами. Отримані результати можна використовувати як ефективний інструмент запобігання або мінімізації впливу алергену на пацієнтів під час сезону Alternaria.Документ Application of pioglitazone in the comprehensive treatment of psoriatic patients with concomitant alimentary obesity(Полтавський державний медичний університет, 2020) Yemchenko, Ya. O.; Ishcheikin, K. Ye.; Kaidashev, I. P.; Ємченко, Яна Олександрівна; Іщейкін, Костянтин Євгенович; Кайдашев, Ігор ПетровичPsoriasis is one of the most common chronic recurrent systemic autoimmune multifactorial diseases, in which the skin, joints, internal organs and systems of the body are involved in the pathological process. Despite the significant preva-lence of psoriasis and a large number of studies on this problem, there is still no single view on the pathogenesis of this dermatosis. To objectively understand the pathogenesis of psoriasis, it is necessary to take into account the insufficiently studied comorbidity of this pathology. Recently, an indisputable link between psoriasis and obesity has been proven. The scientific literature widely covers the issue of identical pathogenetic mechanisms of inflammatory processes in psoriasis and obesity. Given the current data on the role of systemic inflammation underlying the development of both psoriasis and obesity, the study of molecular mechanisms of its development and taking into account the role of proinflammatory nuclear transcription factors, thiazolidinediones are the pathogenetically justified drugs of choice for treatment of these diseases. In this study, we determined the effectiveness of using 15 mg of pioglitazone once a day for 6 months in the treatment of patients with extensive psoriasis vulgaris of moderate severity and concomitant grade І-ІІ alimentary obesity by clinical and immunological examination of systemic inflammation. Analyzing the results of the study, it was found that long-term use of pioglitazone, even in small doses, led to a decrease in systemic inflammation and con-tributed to a milder course of psoriasis in recurrence of the disease.Документ Possibilities of electro-photonic emission analysis in the representation of system information energy processes of the human organism(Українська медична стоматологічна академія, 2020) Nevoit, G. V.; Невойт, Ганна Володимирівна; Невойт, Анна ВладимировнаThe aim of the study is to assess the clinical and diagnostic capabilities of electro-рhotonic emission analysis in the reflection of systemic information energy processes of the human body to increase the effectiveness of measures to prevent and treat NCDs by improving their diagnosis and prevention through the introduction of modern science-intensive technologies and scientific magnetoelec-trochemical concept of metabolism. The results of the оpen, non-randomized, controlled study of 56 functional respondents who do not systematically engage in sports are presented. The electroрhotonic emission analysis was performed on a certified measuring device Bio-Well GDV Camera 2.0 (Bio-Well, Russia-USA). Different levels of functional status and different degrees of health were established as a result of the study. The method of electrophoton emission analysis allows us to calculate the parameters of the state of metabolism of substances at the tissue level and indirectly assess the general functional state of patients based on data processing regarding the intensity and nature of localization of photon emission from the fingers of the respondent. The method for the electro-рhotonic emission analysis is recom-mended by the authors for possible use in clinical medicine in order to objectively assess the energy status of the pa-tient.Документ Hedging Strategies in the English Academic Discourse(2020) Lysanets, Yu. V.; Bieliaieva, O. M.; Purdenko, T. Yu.; Ostrovska, L.; Morokhovets, H. Yu.; Беляева, Елена Николаевна; Бєляєва, Олена Миколаївна; Лисанец, Юлия Валериевна; Лисанець, Юлія Валеріївна; Мороховець, Галина Юріївна; Мороховец, Галина Юрьевна; Пурденко, Тетяна Йосипівна; Островська, Людмила Йосипівна; Пурденко, Татьяна Иосифовна; Островская, Людмила ИосифовнаThe article considers the communicative status of hedging in different genres of the English academic discourse. As a linguistic phenomenon, hedging is associated with the choice of a particular communication strategy, usually aimed at reducing the categorical nature of expressions. Hedging allows authors to limit the degree of reliability or validity of the judgment, to take off responsibility for accuracy of information in a statement, and to avoid critical interpretation. The English language training of researchers and teaching staff at medical universities has become a priority task in higher medical education. Therefore, the aim of the study was to examine and systematize the most common challenges in dealing with hedging linguistic constructions in the English academic discourse. The ability to understand and use hedging phrases correctly is an essential prerequisite of successful communication, intercultural reciprocal understanding and international cooperation in the context of rapid development of integration in Ukraine, which renders the present research relevant. The most commonly used hedging constructions, their significance and contextual role in professional communication have been analyzed. The authors have studied the linguistic features of hedging markers, and the functions of hedging constructions depending on the addresser’s intentions. The material of the research is the corpus of research articles and case reports obtained by the method of continuous sampling from the electronic database of medical publications “PubMed”. The analysis of hedging strategies is important to eliminate possible mistakes and avoid misunderstanding in medical communication. The study of the functional implementation of hedging on the basis of certain academic genres of the English medical discourse specifies the "doctor – patient" communicative situation, motivates the communicative behavior of narrative figures, and optimizes international professional communication. The authors believe that paying due attention to this linguistic phenomenon within the framework of the training PhDs and academic staff will promote scientific cooperation, thus contributing to the development of higher medical education in Ukraine.