Please use this identifier to cite or link to this item:
Title: Periodontal response to cytostatic drugs in children
Authors: Popelo, Yuliia V.
Tkachenko, Pavlo I.
Lokhmatova, Natalia M.
Попело, Юлія Вікторівна
Ткаченко, Павло Іванович
Лохматова, Наталія Михайлівна
Issue Date: 2021
Publisher: Wydawnictwo Aluna
Citation: Popelo Yu. V. Periodontal response to cytostatic drugs in children / Yu. V. Popelo, P. I. Tkachenko, N. M. Lokhmatova // Wiadomosci Lekarskie. – 2021. – Vol. LXXIV, Issue 6. – P. 1322–1325.
Abstract: The aim: To study the effect of different types of cytostatic drugs on the periodontium in children with malignant tumors. Material and methods: The material for generalization was based at the results of examination of 44 patients with malignant tumors of the abdominal cavity who underwent preoperative treatment in the oncohematology department of Poltava Children’s City Clinical Hospital. Results: In the absence of proper dental care in patients of this group, under the influence of chemotherapeutic drugs, significantly worsens the level of oral hygiene and the condition of periodontal tissues. There are also changes in the process of differentiation of the epithelial structures of the gingival margin, which is accompanied by an increase in smears - reprints of the number of inflammatory cells of the peripheral blood, both with preserved structure and destructive forms. Conclusions: In children with malignant tumors, during antitumor therapy, there is a decrease in the level of hygiene of the oral cavity, accompanied by morphological destructive changes in the integumentary epithelial layer of the gingival margin. The severity of these disorders depends on the type and dose of cytostatic drugs, which should be considered in the formation of treatment and prevention measures for them.
Keywords: children
malignant tumors
DOI: 10.36740/WLek202106106
Appears in Collections:Наукові праці. Кафедра дитячої хірургічної стоматології

Files in This Item:
File Description SizeFormat 
Periodontal_response.pdf233,68 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.