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Title: «Simbiter Omega» Multiprobiotic: A New Aid in Treatment of Generalized Chronic Periodontitis
Other Titles: Мультипробіотик "Симбітер омега": новий підхід в лікуванні хронічного генералізованого пародонтиту
Authors: Микитенко, Андрій Олегович
Непорада, Каріне Степанівна
Янковський, Дмитро Станіславович
Берегова, Тетяна Володимирівна
Димент, Галина Семенівна
Mykytenko, A. O.
Neporada, K. S.
Yankovskiy, D. S.
Dyment, G. S.
Berehova, T. V.
Issue Date: 2015
Publisher: J. Dent. Oral Disord. Ther.
Citation: «Simbiter Omega» Multiprobiotic: A New Aid in Treatment of Generalized Chronic Periodontitis / A. O. Mykytenko, D. S. Yankovskiy, G. S. Dyment [et al] // J. Dent. Oral Disord. Ther. – 2015. – Vol. 3(1). – P. 1–6.
Abstract: Contemporary treatment of generalized chronic periodontitis is based on elimination of periodontal pathogens by antibiotics and antiseptics after local scaling and administration of cytoprotectors, immunomodulators and osteotrophic drugs for oral rehabilitation. Current concept distinguishes three levels of protection: the biofilm, which normally should be in dynamic equilibrium of competitive antagonism of periodontal pathogens and symbiotic normoflora; a natural barrier, presented by oral mucosa epithelium; the system of general and tissue immunity. Under certain circumstances, degradation of one of the protective layer leads to imbalance and total insufficient protection. Consequently, we hypothesize that such therapy will result in destruction of the first protective layer, i.e., oral microbiota microbiocoenosis imbalance. Therefore, monotherapy with “Simbiter omega” multiprobiotic is the effective supplement for common therapy, since it promotes restoration of all oral mucosa protective layers against the background of antagonist fighting of colonies of Bifidobacterium, Lactobacillus, Lactococcus, Streptococcus, Propionibacterium and Acetobacter with periodontal pathogens Actinobacillusactynomycetemcomitans, Porphyromonasgingivalis, Bacteroidesforsythus mainly. Omega-3 and omega-6 essential polyene fatty acids and smectite, containing in multiprobiotic, have synergizing parodontoprotective effect.
Keywords: multiprobiotic
omega-3 essential polyene fatty acid
хронічний генералізований пародонтит
омега-3 есенціалні поліненасичені жирні кислоти
Appears in Collections:Наукові праці. Кафедра біологічної та біоорганічної хімії

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