The Influence of Pioglitazone on NFkB Expression in CD40+ OrO Lymphocytes is Polymorphism-Dependent
Ескіз недоступний
Дата
2009
Назва журналу
Номер ISSN
Назва тому
Видавець
Washington
Анотація
Expression of CD40 cells was unchanged in control or P cul tures. Expression of NFkB in CD40-positive cells significantly increased in all control cultures after 24 hours incubation. Addition of P to MNC in duced from 5 to 25% dose-dependent decrease in NFkB expression. The impact of P on CD40+ cells with the Prol2Ala polymorphism of PPAR- 7 was greatest on MNC from patients bearing the Alal2 allele.
Опис
Ключові слова
Бібліографічний опис
The Influence of Pioglitazone on NFkB Expression in CD40+ OrO Lymphocytes is Polymorphism-Dependent : abstract sessions the 2009 AAAAI ANNUAL Meeting, March 13–17, Washington / I. P. Kaidashev, N. Kutzenko, O. Shlykova, L. M. DuBuske // The jornal of allergy and clinical immunology. – 2009. – Vol. 123, № 2. – P. 343.