Please use this identifier to cite or link to this item:
Title: Churg-strauss syndrome: clinical case and its feautures
Authors: Katerenchuk, Ivan P.
Tkachenko, Lidiya A.
Yarmola, Tetyana I.
Rustamyan, Savetik T.
Pustovoyt, Anna L.
Katerenchuk, Oleksandr I.
Катеренчук, Іван Петрович
Ткаченко, Лідія Афанасіївна
Ярмола, Тетяна Іванівна
Рустамян, Сатєнік Тігранівна
Пустовойт, Ганна Леонідівна
Катеренчук, Олександр Іванович
Issue Date: 2019
Publisher: Wydawnictwo Aluna
Citation: Churg-strauss syndrome: clinical case and its features / I. P. Katerenchuk, L. A. Tkachenko, T. I. Yarmola, V. V. Talash, S. T. Rustamyan, A. L. Pustovoyt, O. I. Katerenchuk // Wiadomosci Lekarskie. – 2019. – T. LXXII, nr. 4. – P. 723–726.
Abstract: Introduction: Autoimmune uveitis (AU) is an inflammation of the uvea due to an autoimmune reaction to self-antigens. There are no standardized treatment protocols for AU. A new class of drugs called biologics, that target the various mediators of the inflammation cascade, may potentially provide more effective and less toxic corticosteroids treatment of AU. The aim: The aim of this review was to make the evaluatation of the interleukins influence on intraocular inflammation in available literature and summarize the expediency of using anti-interleukins agent in case of AU. Material and methods: This article is a review and summary of the up-to-date results of pivotal experimental and clinical trials targeting the Interleukins (IL), including IL-6, IL-10, IL-17, IL-22, IL-23, and tumor necrosis factor alpha (TNF-α). Also reviews focus on the potential use of anti-interleukin therapy for the treatment of autoimmune diseases (AD). Conclusions: AU is an inflammation of the uvea due to an autoimmune reaction to self-antigens. The most important IL in the pathogenesis of AU are IL-6, IL-10, IL-17, IL-22, IL-23 and TNF-α. Anti-interleukin therapy is partially described. Future randomized controlled trials are urgently needed to be conduct.
Keywords: autoimmune uveitis
anti-interleukin therapy
tumor necrosis factor alpha
ISSN: 0043-5147
Appears in Collections:Наукові праці. Кафедра внутрішньої медицини № 2

Files in This Item:
File Description SizeFormat 
Churg_strauss_syndrome_clinical_case.pdf410,85 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.