Клінічне обґрунтування використання препарату “Oral Blue ” для лікуванні хронічного катарального гінгівіту

Abstract

В даному дослідженні нами проаналізована клінічна ефективність препарату “Oral Blue” на основі антисептику “Troklosene” для лікування хронічного катарального гінгівіту у хворих без супутньої патології. Динаміка клінічних показників, а саме: гігієнічного індексу OHI-S Green-Vermillion, проби Шиллера-Писарєва, індексу РМА в модифікації С. Parma, КПІ за П.А. Леусом та скорочення курсу лікування свідчать на користь запропонованого нами методу комплексного лікування даної патології.; В данном исследовании нами проанализирована клиническая эффективность препарата “Oral Blue” на основе антисептика “Troklosene” для лечения хронического катарального гингивита у больных без сопутствующей патологии. Динамика клинических показателей, а именно: гигиенического индекса OHI-S Green-Vermillion, пробы Шиллера-Писарева, индекса РМА в модификации С. Parma, КПИ по П.А. Леусу и сокращение курса лечения свидетельствуют в пользу предложенного нами метода комплексного лечения данной патологии.; Chronic catarrhal gingivitis (CCG) is the most common pathology among periodontal tissue diseases, it’s prevalence reaches 98%, affecting mainly young people. The purpose of our research was to study the clinical efficiency of chronic catarrhal gingivitis therapy using the “Oral Blue” based on the antiseptic “Troklosene in the scheme of complex treatment. The subject of the study were 24 patients with CCG of moderate severity, which did not have a general-somatic pathology. Among them - 14 women (58%) and 10 men (42%). The age of the patients ranged from 25 to 35 years. CCG was diagnosed according to generally accepted clinical criteria. For an objective characterization, an index evaluation of the state of periodontal tissues was used. Depending on the treatment scheme, patients with CCG were divided into two groups - the main (14 patients) and control (10 patients). The therapy of chronic catarrhal gingivitis was carried out in accordance with the treatment protocol for this pathology. For local anti-inflammatory therapy, a 0,06% chlorhexidine solution and a “Metrogyl-Denta” gel were used. Patients in the main group, in addition to standard baseline therapy, were given “Oral Blue”, which is water soluble effervescent tablets based on the antiseptic “Troklosene”. The effectiveness of the treatment was determined on the basis of objective periodontal indices before and after the completion of treatment course. The effectiveness of treatment for patients of main group was 97,8%, whereas the effectiveness for patients of the control group was 87,6%. The number of visits for patients of the main group was 6,5 and for patients of the control group it was 8,5 (P <0,05). The therapy effectiveness is also confirmed by the dynamics of clinical indicators, which we have generalized for patients of the main and control groups. After the course of complex therapy, the values of OHI-S Green-Vermillion GI were significantly reduced for patients of the main group - from 2,63 ± 0,59 to 0,33 ± 0,03 (P <0,01); for patients of control group, the index changes were less significant - from 2,62 ± 0,33 to 0,88 ± 0,07 (P <0,01). The Schiller-Pisarev test for patients of the main group changed from positive to negative (P <0,01), and for the control group it changed from positive to weakly positive or negative (P <0,05). After treatment the value of PMA index in the С. Parma modification significantly decreased for patients of the main group - from 42,75 ± 2,42 to 9,28 ± 1,28 (P <0,01); for patients of the control group the indicators decreased less significantly - from 40,03 ± 2,15 to 19,55 ± 1,77 (P <0,01). The value of KPI by P.A. Leus also significantly decreased for the main group - from 0,74 ± 0,18 to 0,19 ± 0,07 (P <0,05), and for the control group the reduction of these indicators was expressed less - from 0,73 ± 0,16 to 0,25 ± 0,24 (P <0,05). Thus, analyzing the dynamics of the obtained clinical indicators, we can conclude that the condition of periodontal tissues has considerably improved in patients who additionally used the "Oral Blue" based on the antiseptic "Troklosene" in the complex therapy of chronic catarrhal gingivitis.