Кристалографічні методи дослідження ротової рідини в комплексному обстеженні стоматологічних пацієнтів

Abstract

Досліджено особливості мікрокристалізації ротової рідини в пацієнтів із підвищеною стертістю зубів на основі кристалографічного аналізу. Отримано п’ять основних видів орієнтації кристалів при висушуванні ротової рідини, що надалі можна використовувати для адекватної діагностики та вибору профілактичних заходів при різній стоматологічній патології; Исследованы особенности микрокристаллизации ротовой жидкости у пациентов с повышенной стертостью зубов на основе кристаллографического анализа. Получено пять основных видов ориентации кристаллов при высушивании ротовой жидкости, что в дальнейшем можно использовать для адекватной диагностики и выбора профилактических мероприятий при различной стоматологической патологии; The main mineralization function in the mouth takes saliva, which in most cases are aimed at maintaining physiological balance, reformatting processes, demineralization of tooth enamel and permanent compound of the surface layer after various kinds of negative influences. In scientific research and medical practice, considerable attention is given to facilitate the differential diagnosis of the laboratory methods. Mineralization potential of saliva may assess the nature of microcrystalization. In various pathological conditions in the body, crystallization feature of the saliva reflects not only local, but also common reactions. When dehydration of the oral fluid, structure formation occurs with the specific interactions of structural components (except physical laws and environmental conditions), it allows them to be analyzed. The principle of the method is the ability of a substance to crystallize on drying to form crystals of different shapes and different orientations in space. Assessment of crystalogram performed macroscopically - the number of crystallization centers and nature of drawing and microscopically - structure and changing crystals. In the study, we tried to reveal the mechanisms of protein structure in the drops of oral fluid dehydration. With the use of "native Crystallography" attempt to create expert evidence saliva dry phase followed by translation and processing crystalogram in image editors. The result of our studies is database of typical structures of solid oral liquid phase, which will allow us to classify the micro types on biochemistry. From the analysis of the morphology of prototypes can say that we have identified several types of which the structure of the samples: the inclusion of one or more crystals, the size of 0.5-2 microns (a) * crystals over a decade, larger than 5 microns (b) * dendritic or as a "tree" structure (c) * needle structure (d) * threads that can make "delicate" cellular structure (e) These methods for studying morphological features solid phase biological fluids with varying success used in various fields of medicine, including dentistry. The oral cavity directly related to the gastrointestinal tract, so changes in it will be directly related to changes in microcrystalization of the oral fluid that should be considered when establishing the diagnosis. Summarizing our results, we can say that the human body works as a unit. Changing individual components in the system must lead to complications or irregularities in the system as a whole. So exploring features of crystal formation will allow us to define types of the microcrystalization in different types of dental pathology.