Будь ласка, використовуйте цей ідентифікатор, щоб цитувати або посилатися на цей матеріал:
http://repository.pdmu.edu.ua/handle/123456789/8733
Повний запис метаданих
Поле DC | Значення | Мова |
---|---|---|
dc.contributor.author | Shaienko, Z. O. | - |
dc.contributor.author | Bobyreva, L. Ye. | - |
dc.contributor.author | Шаєнко, Златослава Олексіївна | - |
dc.contributor.author | Бобирьова, Людмила Єгорівна | - |
dc.date.accessioned | 2018-10-10T07:10:26Z | - |
dc.date.available | 2018-10-10T07:10:26Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Shaienko Z. O. Combination of Metformin and Pioglitazone and its Effect in Treatment of Comorbid Pathology / Z. O. Shaienko, L. Ye. Bobyreva // Wiadomości Lekarskie. – 2018. – № 2, P. ІІ. – P. 278–280. | uk_UA |
dc.identifier.uri | http://repository.pdmu.edu.ua/handle/123456789/8733 | - |
dc.description.abstract | Introduction: The early development and high incidence of cardiovascular lesion in patients with type 2 diabetes mellitus is one of the most serious challenges for the diabetology worldwide. Aim: The purpose of the paper is to determine the dynamics of the insulin resistance indices in patients with type 2 diabetes mellitus concomitant with coronary heart disease in the combination therapy with metformin and pioglitazone during 3 and 6 months. Materials and Methods: 95 patients with type 2 diabetes mellitus and coronary heart disease have been treated and randomized into two groups: the comparison group (n=37), treated with metformin and sulfonylureas, and the study group (n=58), treated with metformin in combination with pioglitazone. Prior, after 3 and 6 months of treatment C-peptide was assessed and index of the insulin resistance was calculated. Results: The resulting data proved the statistically significant lowering of the markers and level of the insulin resistance under the effect of combination treatment with metformin and pioglitazone. Conclusions: The proposed variant of the combination therapy has a positive effect on the clinical course of the coronary heart disease in patients with type 2 diabetes mellitus, well tolerated by the patients and can be considered as the pathogenetic factor in the treatment of these diseases. | uk_UA |
dc.language.iso | en | uk_UA |
dc.publisher | Wiadomosci Lekarskie | uk_UA |
dc.subject | diabetes mellitus | uk_UA |
dc.subject | coronary heart disease | uk_UA |
dc.subject | insulin resistance | uk_UA |
dc.title | Combination of Metformin and Pioglitazone and its Effect in Treatment of Comorbid Pathology | uk_UA |
dc.type | Article | uk_UA |
Розташовується у зібраннях: | Наукові праці. Кафедра ендокринології з дитячими інфекційними хворобами |
Файли цього матеріалу:
Файл | Опис | Розмір | Формат | |
---|---|---|---|---|
Combination_of_metformin.pdf | 335,58 kB | Adobe PDF | Переглянути/Відкрити |
Усі матеріали в архіві електронних ресурсів захищені авторським правом, всі права збережені.