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Документ Adverse factors that can affect on the course of chronic parenchimatic parotitis in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Bilokon, S. O.; Popelo, Yu. V.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія МиколаївнаThe aim: The study of the presence of disorders in the ante- and postnatal periods of development of children from 2 months to 15 years with chronic parenchimatic parotitis, which may affect its course. Materials and methods: It has been examined and treated 88 children, aged from 2 months to 15 years with chronic parenchimatic parotitis, and their mothers were interviewed, who indicated the pathological course of pregnancy, childbirth and indicated the type of breastfeeding babbies. The scope of the survey included general, additional methods, consultations by related specialists and statistical processing of results. Results: 88 children with the exacerbation of chronic parenchimatic parotitis were examined (42 – (47%) with active course and 46 – (53%) with inactive). The exacerbation occurred on the background of acute infectious processes or coincided with the exacerbation of one of the chronic diseases. The first manifestations occurred in spring (55%) and autumn (36%) periods, 44% of children were hospitalized with other diagnoses. The presence of pathological conditions during pregnancy and birth defects in their mothers were recorded more often 3,5 and 3,3 times, respectively, compared with control. 70% of children received mixed and artificial feeding and were more likely to become ill. Conclusions: The severity of clinical manifestations of inflammation and disorders of the general condition depended on the activity of the course of chronic parenchymatic parotitis and were more pronounced when active. During the remission period, no apparent clinical manifestations were detected in 72% of observations, however, in 28%, the identified signs indicated a latent course, which required additional treatment and rehabilitation measures.Документ Bitten wounds of the maxillofacial area in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Bilokon, S. O.; Dolenko, O. B.; Korotych, N. M.; Popelo, Yu. V.; Bilokon, N. P.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Попело, Юлія Вікторівна; Білоконь, Наталія ПавлівнаThe aim of the work is to determine the frequency, structure, features of clinical manifestations and treatment of bitten wounds of the face and neck in children of Poltava region. Materials and methods: It has been analyzed 91 histories of disease of thematic patients undergone treatment at the Surgical Department of Pediatric town clinical hospital of Poltava. Results: In the structure of traumatic injuries of maxillofacial area in children 5.3% were patients with bitten wounds of the face and neck. Among the injured were children of the age 7-12 years old (30.2%). In 74.7% of cases, the bites were complicated by acute inflammatory processes. Urban residents accounted for 71.8% of the total number of cases, while rural residents accounted for 28.2%. Boys were injured by 53.6% and girls by 46.4%. Sharps (74.5%), punctures (19.3%) and lacerations (6.2%) differed in form. The comprehensive treatment of patients with bitten maxillofacial area wounds was carried out according to the protocol of care. Conclusions: The clinical picture and severity of bitten wounds of maxillofacial area in children have individual features, which are largely due to topographic and anatomical localization of injuries. The choice of the optimal variant of primary surgical treatment of wounds and the amount of surgery should be determined individually depending on the severity of the injury, the time of injury. Special attention should be paid to normalization of psycho-emotional state of patients and prevention of scar formation.Документ Clinical and morphological features of follicular cysts of jaw in children(2023) Tkachenko, P. I.; Bilokon, S. O.; Dolenko, O. B.; Lokhmatova, N. M.; Popelo, Yu. V.; Korotych, N. M.; Bilokon, Yu. S.; Lachabi, Reda; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Попело, Юлія Вікторівна; Коротич, Наталія Миколаївна; Білоконь, Юлія СергіївнаДокумент Clinical characteristic of different types of conservative treatment os pathological scars of head and neck(Полтавський державний медичний університет, 2023) Tkachenko, P. I.; Lokes, K. P.; Bondarenko, V. V.; Bilokon, S. O.; Ivanytska, O. S.; Rezvina, K. Y.; Ivanicky, I. O.; Ткаченко, Павло Іванович; Локес, Катерина Петрівна; Бондаренко, Валерій Володимирович; Білоконь, Сергій Олександрович; Іваницька, Олена Сергіївна; Резвіна, Катерина Юріївна; Іваницький, Ігор ОлексійовичThere are a lot of different types of conservative and surgical treatment of pathological scars. The purpose of study was to analyze the result of using of ultraphonophoresis of Contractubex and electrophoresis with lidase in case of conservative treatment of scars of maxillofacial region. The study involved 40 patients of the Department of Maxillofacial Surgery of the Poltava Regional Clinical Hospital with pathological scars of maxillofacial localization. All patients were divided into two clinical groups of 20 people each. Patients of the first clinical group were administered the Contractubex daily using ultraphonophoresis. Patients of the second clinical group underwent electrophoresis with lidase. The nature of the scars was assessed by four clinical signs (type, texture, color and sensitivity), expressed on a 4-point scale. Both methods of conservative treatment of maxillofacial scars have a predominant effect on subjective indicators, such as itching. A more pronounced effect of treatment was noted after the use of ultraphonophoresis of contractubex, in this group of patients there was also a significant improvement in such an objective clinical indicator as the color of the scar. The use of lidase electrophoresis led only to a reliable improvement in subjective feelings (P4), in the absence of such in relation to three objective indicators. Thus, the investigated methods of conservative treatment mainly affect the subjective characteristics of scar tissue. Moreover, the use of contractubex ultraphonophoresis has a more pronounced effect than the use of lidase electrophoresis.Документ Clinical-morphological characteristics and peculiarities of treatment of paraururicular fistulas in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Popelo, Yu. V.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Hohol, A. M.; Bilokon, N. P.; Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Гоголь, Андрій Михайлович; Білоконь, Наталія ПавлівнаThe aim: Determining the frequency of occurrence of paraauricular fistula in children and comparing the results of their own experience regarding their clinical manifestations, treatment principles and morphological features with existing scientific data. Materials and methods: The results of a comprehensive examination and surgical treatment of 25 children with paraauricular fistulas. Results: Most often, para-auricular fistula was observed in infants 22 – (88%). In 18 persons (72%), they were unilateral, in 10 – (40%) hereditary. In 8 – (32%), fistula was diagnosed immediately after birth. In 17 – (68%) the pathology was not clinically manifested, but was an accidental finding during the next medical examination. Morphological research has shown that congenital paraauricular fistula is a formed canal intimately associated with the epithelium and cartilage, and the presence of epithelial lining on the fistula wall with constant support of the inflammatory process makes it impossible to heal even against the background of multicomponent treatment. Conclusions: Due to the topographic-anatomical localization, features of the clinic of the born fistula, surgical treatment does not always allow to achieve the desired results, and requires repeated interventions during recurrence. It is possible to prevent recurrence by the extensive use of additional diagnostic manipulДокумент Clinicomorphological characteristics of the wound process at the early postoperative period after radical uranostaphyloplasty(Українська медична стоматологічна академія, 2019) Tkachenko, P. I.; Dolenko, О. B.; Lokhmatova, N. M.; Bilokon, S. O.; Dobroskok, V. O.; Ткаченко, Павло Іванович; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Білоконь, Сергій Олександрович; Доброскок, Віталіна Олексіївна; Ткаченко, Павел Иванович; Доленко, Ольга Борисовна; Лохматова, Наталия Михайловна; Белоконь, Сергей Александрович; Доброскок, Виталина АлексеевнаThe purpose of the paper was to study the clinical situation and the morphological structure of the biopsy material of the hard palate mucoperiosteal grafts in children with the congenital cleft palate before surgery and at the early postoperative period after radical uranostaphyloplasty. The study of clinical characteristics and general somatic state of children with this pathology before operative intervention enables to reveal the marked anatomical and functional disorders. The study of the wound process at the early postoperative period after radical uranostaphyloplasty with the help of morphological structure of the biopsy material of the hard palate mucoperiosteal grafts enables to predict the degree of probability of the formation of dense scar and make individual plan of treatment-and-prophylactic and rehabilitation measures for this category of patients. Метою роботи було вивчення клінічної ситуації та морфологічної структури біоптатів слизово-окісних клаптів піднебіння у дітей з його вродженими незрощеннями до оперативного втручання та в ранньому післяопераційному періоді після радикальної ураностафілопластики. Дослідження клінічної характеристики та загально соматичного стану у дітей з цією патологією до оперативного втручання дозволило виявити у них виражені анатомічні та функціональні порушення. Вивчення ранового процесу в ранньому післяопераційному періоді після радикальної ураностафілопластики за допомогою морфологічної структури біоптатів слизово-окісних клаптів піднебіння дає змогу спрогнозувати ступінь вірогідності формування щільного рубця, та скласти індивідуальний план лікувально-профілактичних і реабілітаційних заходів для цієї категорії хворих.Целью работы было изучение клинической ситуации и морфологической структуры биоптатов слизистонадкостничных лоскутов неба у детей с его врожденными несращениями до оперативного вмешательства и в раннем послеоперационном периоде после радикальной ураностафилопластики. Исследование клинической характеристики и общего соматического состояния у детей с этой патологией до оперативного вмешательства позволило выявить у них выраженые анатомические и функциональные нарушения. Изучение раневого процесса в раннем послеоперационном периоде после радикальной ураностафилопластики с помощью морфологической структуры биоптатов слизисто-надкостничных лоскутов неба позволяет спрогнозировать степень достоверности формирования плотного рубца, и составить индивидуальный план лечебно-профилактических и реабилитационных мероприятий для этой категории больных.Документ Diagnostic information of computed tomography of the upper jaw in patients required implant rehabilitation(Wydawnictwo Aluna, 2018) Tkachenko, P. I.; Pankevych, A. I.; Kolisnyk, I. A.; Gogol, A. M.; Ткаченко, Павло Іванович; Панькевич, Артур Іванович; Колісник, Інна Анатоліївна; Гоголь, Андрій МихайловичIntroduction: Dental implantation in conditions of bone deficiency in the loss of lateral group of teeth of the upper jaw is impossible without the maxillary sinus floor augmentation. Preparation for surgical intervention requires a thorough assessment of the anatomical features of the sinus, relationship between the sinus and adjacent teeth, detection of foci of chronic infection of the Schneiderian membrane. In the complex of the objective methods of investigation, computed tomography is the most informative approach to study the state of the bone and soft tissue structure of the sinus. The aim of the paper is to evaluate the state of the bone structures and maxillary sinus membrane to determine the technique for selection the optimum alternative for management of patients, who required sinus lift, based on the computed tomography. Materials and methods: Computed tomographic examination of 206 patients with bounded and free-end edentulous spaces in the lateral area of the upper jaw was carried out over a period of 2010-2017 to evaluate the appropriateness of sinus lift approach and selection of its technique. The state of the bone tissue and presence of the auxiliary septa, intranasal structures, including ostiomeatal complex, presence of edema and exudates, lesions of the mucosa, as well as the state of ostium maxillaris has been estimated. Results: In the projection of the maxillary sinus the thickness of the bone tissue ranged within 1 mm to 10,5 mm; the density of bone tissues was of the D3-D4 type. Inflammatory events were detected in 60,1%, including: thickening of the mucous membrane on the right and on the left (40,6% and 41,1%, respectively), the total edema (8,6% and 9,7%, respectively). Bilateral thickening was found in 38,8%, and bilateral total edema in 28,0% of cases. Remnants of the filling material were found in 1,4% of sinuses on the right and in 2,8% on the left. Bone septum was visualized on the right in 18,8%, and in 17,4% on the left, bilateral in the 31,8%. Cystic masses were detected on the right in 4,2% of cases and in 6,2% on the left, bilateral in 16,7%. Conclusions: Computed tomographic examination provides thorough evaluation of the parameters of the bone tissues, state of mucous membrane and peculiarities of architectonics of maxillary sinuses at the pre-implantation stage.Документ Difficulties of the diagnosis and treatment of dermoid and epidermoid cysts of the maxillofacial area and the neck among children(Національний медичний університет імені О. О. Богомольця, 2020) Tkachenko, P. I.; Bilokon, S. O.; Bilokon, Y. S.; Shevchuk, A. R.; Fleischhauer, S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Білоконь, Юлія СергіївнаIt is generally accepted that dermoid and epidermoid cysts are the result of malformation of the ectoderm. The asymptomatic course, absence of pathognomonic symptoms and similarity of clinical manifestations at separate stages of growth, despite nosological form and place of occurrence, give this pathology of particular relevance in the practice of pediatric maxillofacial surgery. However, if there are no significant issues regarding the etiology and pathogenesis of dermoids and epidermoids, there is a problem of constant monitoring of their prevalence and structure for the formation of administrative organizational measures for the planning of specialized care for this category of patients. Special attention should also be given to the development of new, minimally invasive surgical interventions, given the increasing aesthetic demands and requirements of patients. The aim of the study is to study in a comparative aspect their own experience on the clinical and morphological features and principles of treatment of dermoid and epidermoid cysts of the maxillofacial area and neck in children with the results of scientific studies, covered in literature. A thorough analysis of fundamental scientific works and publications in periodicals devoted to the scientific development of various directions in relation to these issues is carried out. The clinical section of the work concerns 15 children with dermoids and 8 children with epidermoids who have been treated for 8 years in the surgical ward of the children’s clinical hospital in Poltava. General clinical, additional, and specific examination methods were used to establish clinical diagnosis, including diagnostic puncture, ultrasound, and MRI examination, which was performed in complex and questionable cases. If necessary, the patients were consulted by doctors of related specialties. The microscopic structure of the postoperative material was studied on preparations made by conventional methods. An objective study found that the clinical picture of the dermoid and epidermoid cysts is similar, differing only in slight subjective sensations on palpation. Comparison of clinical diagnosis and results of postoperative morphological verification of removed soft tissue bones showed that in 23.9% of patients the clinical diagnosis did not coincide with pathohistological. The difference in dermoids was the largest (75.0%), which confirms the need for expanded use of additional examination methods both at the prehospital stage and under inpatient conditions immediately before surgery. In general, the obtained morphological picture of the postoperative material coincided with the literature data on the classical structure of the dermoid and epidermoid cysts of the soft tissues of the maxillofacial area. Thus, the dermoid and epidermoid cysts of the maxillofacial area in children, having a dysontogenic origin, are most often diagnosed at younger and older school age. Despite their classic clinical picture, a considerable number of discrepancies between clinical and pathohistological diagnoses are traced, requiring a careful examination at both the hospital and hospital stages using modern, informative supplementary and special methods of investigation in complex and doubtful cases of cases and complex cases. These materials may be the basis for further in-depth scientific studies on immunohistochemical structural features dermoids and epidermoids to determine immunocompetence layers cystic membranes and determine their probable role in causing acute inflammation depending on the type of formation.Документ Difficulties of the diagnosis and treatment of traumatic and aneurysmal cysts of the jaws(Національний медичний університет імені О. О. Богомольця, 2020) Tkachenko, P. I.; Bilokon, S. O.; Shevchuk, A. R.; Bilokon, Y. S.; Fleischhauer, S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Білоконь, Юлія СергіївнаThe great diversity of the jaw cysts makes the issues of their diagnosis, differential diagnosis and treatment quite important, always requiring individual approach, given the features of each clinical case. Although the jaw cysts were first mentioned by Scultetus in 1654, the researchers still have different views on the semiotics and group belonging of individual nosological forms in the classifications and, consequently, on120 the choice of treatment method, prevention of possible complications and recurrences, and making prognosis. Asymptomatic clinical course and absence of characteristic clear clinical manifestations of the jaw cysts, similarity of their signs at separate stages of the development, regardless the nosological form and site of origin, make this pathology relevant in the practice of maxillofacial surgery. Traumatic and aneurysmal pseudocysts are common in the nomenclature of tumor-like formations of the jaws. The paper is concerned the etiology and pathogenesis, clinical morphological features and modes of treatment of traumatic and aneurysmal jaw cysts, based on the generalization of the findings of the scientific researches, to emphasize the above nosological forms to the medical community. The study encompassed the thorough analysis of the fundamental scientific works and publications in periodicals on above issues. The clinical part of the study concerned a comprehensive examination of 46 children with traumatic and aneurysmal jaw cysts who received treatment at the surgical unit of the Poltava Municipal Children’s Clinical Hospital during the period of 5 years. In addition, 8 adult patients with traumatic cysts were examined and received outpatient treatment at the Department’s clinic. Common clinical and additional examination methods, diagnostic puncture, EOD, radiography, CT and MRI were used to make the clinical diagnosis in serious cases. The microscopic structure of the specimens made from the postoperative material using conventional techniques, was studied. During 2014-2019, 46 children with neodontogenic jaw cysts (NJC) were treated at the Department of Children’s Oral Surgery, including 24 patients (52.2%) with traumatic cysts (TC) and 15 patients (32.6%) with aneurysmal cysts (AC). That is, TC and AC were accounted for 39 cases (84.8%) of NJC. At the same time, if the general age of patients with NJC ranged from 5 to 15 years, then TC and AC were most common in children aged 10-15 years, which is in concordance with the data of other researchers, who mark their highest percentage in puberty. 25 (64,1%) boys and 14 girls (35.9%) have been involved into study. Generalized statistical analysis revealed that traumatic cysts accounted for 52.2% of children, 32.6% for aneurysmal, 15.2% for other types of non-odontogenic jaw cysts. Among patients, boys predominated, and even121 trauma in the past medical history does not always correspond and confirm the type of cystic formation. The presented material suggests a rather conditional diagnostic «boundary» between traumatic and aneurysmal cysts, when, in fact, the main differential diagnostic criterion is a carefully gathered anamnesis, even at the prehospital stage. The given material can be the basis for further in-depth scientific and practical studies on the study of immunohistochemical structural features of traumatic and aneurysmal jaw cysts.Документ Effectiveness оf correction of psycho-emotional stress in children with traumatic injury to soft tissues and facial bones(Aluna Publishing, 2021) Tkachenko, P. I.; Lokhmatova, N. M.; Bilokon, S. O.; Popelo, Yu. V.; Dolenko, O. B.; Korotych, N. M.; Pankevych, A. I.; Kolisnyk, I. A.; Ткаченко, Павло Іванович; Лохматова, Наталія Михайлівна; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Доленко, Ольга Вячеславівна; Коротич, Наталія Миколаївна; Панькевич, Артур Іванович; Колісник, Інна АнатоліївнаThe aim: To study the effectiveness of correction of psycho-emotional stress in children with traumatic injuries of the tissues of the maxillofacial area. Materials and methods: A comprehensive examination and treatment of 58 children aged 3 to 15 years with traumatic injuries of the maxillofacial area were conducted during the period of 5 years. This applied to soft tissue injuries in 51.7% of cases and in 48.3% - to facial bone injuries. To test the severity of the psycho-emotional state, two homogeneous groups were formed in a total of 41 persons of primary and secondary school age. Results: A comparison of the results of our previous studies, which concerned only the fact of psychological testing and changes in vegetative balance in children with traumatic injuries with a group of patients who underwent comprehensive treatment with additional involvement of targeted psychoneuropharmacological correction allowed to establish, that this approach made it possible to eliminate vegetative disorders and reduce the degree of stress in them for 9-10 days from the time of hospitalization. Conclusions: In children with traumatic injuries of soft tissues and bones of the face, dysregulation of vegetative function and intensity of compensatory-adaptive mechanisms of the body with the predominance of the central mechanism of regulation. With the additional involvement of the drug “Noofen®” in the complex of therapeutic measures, it allows to stabilize their psychological state, which indicates its effectiveness.Документ Features of the course, clinical and morphological characteristics of ameloblastoma and fibrous dysplasia in children(Полтавський державний медичний університет, 2021) Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Резвіна, Катерина Юріївна; Попело, Юлія Вікторівна; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Коротич, Наталія Миколаївна; Білоконь, Наталія Павлівна; Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Rezvina, K. Yu.; Popelo, Yu. V.; Dolenko, O. B.; Lokhmatova, N. M.; Korotych, N. N.; Bilokon, N. P.У статті висвітлені особливості клінічного перебігу та морфологічних характеристик, діагностичних заходів і лікування дітей з амелобластомою та фіброзною дисплазією щелепних кісток. Відсутність чітких клінічних проявів, подібність симптоматики і характер перебігу амелобластоми та фіброзної дисплазії, що є притаманним для усіх доброякісних пухлин щелепно-лицевої ділянки у дітей, обумовлюють значний відсоток діагностичних помилок, роблячи питання їх диференційної діагностики доволі актуальним для хірургічної стоматології і щелепно-лицевої хірургії.Документ Frequency and structure of benign soft tissue formations in the maxillofacial area(Українська медична стоматологічна академія, 2020) Ткаченко, Павло Іванович; Резвіна, Катерина Юріївна; Швець, Анатолій Іванович; Попело, Юлія Вікторівна; Ткаченко, Павел Иванович; Резвина, Екатерина Юрьевна; Швец, Анатолий Иванович; Попело, Юлия Викторовна; Tkachenko, P. I.; Rezvina, K. Yu.; Shvets, A. I.; Popelo, Yu. V.The article considered our own observation results and retrospective analysis of archival material of the Maxillofacial Department of M.V. Sklifosovsky Poltava Regional Clinical Hospital and Surgical Department of the Poltava City Children's Clinical Hospital from 2008 to 2018. It was found that among adults the number of patients with benign soft tissue formations of the face and neck is 4.9%, and in children – 7.8% of the total number of inpatients. Most of them were bronchiogenic cysts of the lateral part of the neck (152 – 26.3%) and atheromatous plaques (147 – 25.4%). They mostly occured at the age of 22 to 60 years, men suffered more often (205 - 35.5%). The largest number of discrepancies in the diagnosis at the prehospital phase were patients with epidermal cysts – 38 (7.9%). As for pediatric population, their number was 7.8% of the total number of inpatients. Neoplasms of dysontogenetic origin predominate, among which the most common were dermoid cysts – 92 patients (32.4%) and haemangiomas– 74 patients (26%). Less common were ranulae – 36 cases (12.7%), bronchiogenic cyst – 17 cases (6%) and atheromatous plaque – 16 cases (5.6%). They were found more often in the nursery age – from 1 to 3 years.Документ Frequency, structure and clinical manifestations of thermal burns of the jaw-facial area in children(Wydawnictwo Aluna, 2021) Tkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Popelo, Yu. V.; Rezvina, K. Yu.; Hohol, A. M.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Попело, Юлія Вікторівна; Резвіна, Катерина Юріївна; Гоголь, Андрій МихайловичThe aim: To establish the frequency, structure and features of the clinical course of facial and neck burns in children. Materials and methods: During 5 years, 78 patients aged from 6 months to 15 years with isolated burns of the face and neck and in combination with lesions of other anatomical areas were treated. In the dynamics of observation of patients were used classical methods of examination, and in their treatment we followed the protocol of medical care for this category of patients. Results: Thermal injuries of the face and neck accounted for 12.6% of the total number of patients with burns. Their isolated lesion was 26.9%, and in combination with other areas it was 73.1%. The most frequently affected were children of nursery, primary school and preschool age, with a predominance of rural residents (52.6%), mostly boys (78.0%). Anesthesia support had to be used in the treatment of 24 patients (30,8%). The features and nature of the burns depended on the relief of the face and the most damaged are its protruding parts. Conclusions: Open flames were the most common cause of thermal burns of the face and neck in children, and the lesions were combined with burns to the chest, abdomen, and limbs. The main reasons were reckless behavior of children, their increased mobility and lack of care for their relatives. It should be noted that in 3.8% of victims there was a delay in mental and physical development.Документ Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors(Wydawnictwo Aluna, 2019) Popelo, Yu. V.; Tkachenko, P. I.; Bilokon, S. O.; Попело, Юлія Вікторівна; Ткаченко, Павло Іванович; Білоконь, Сергій ОлександровичIntroduction: According to modern standards of treatment of malignant neoplasms conducting polychemotherapy requires up to 90% of cancer patients. However, in addition to the expected cytotoxic effects, it is accompanied by disorders in dental health in the vast majority of patients. The aim: To study the effect of cytostatics on soft tissues of the oral cavity in children with malignant tumors of the abdominal cavity. Materials and methods: Material for writing this scientific work served as a synthesis of results for 25 people aged 7 to 15 years with malignant tumors of the abdominal cavity, in which a comprehensive oral examination was performed to determine the manifestations of dental toxicity cytostatics. Results: At the end of the first course of chemotherapy, all patients had dry redness of the lips, 20 - (80,0%) with eruptions, in 18 - (20,0%) erosion. The Green-Vermillion, PMA, and PBI indices grew by 1,8; 7 and 3,3 times respectively. In cytograms with buccal epithelium an increase in the number of cells of polymorphic sizes and forms with signs of gidropic dystrophy was found. The nuclear-cytoplasmic ratio decreased by 1,4 times compared with the primary examination. Conclusions: This situation creates the preconditions for the development of inflammatory process in the tissues of the oral cavity and requires the use in this category of patients of a substantiated pathogenetic correction of existing disorders.Документ Impregnation of oral mucosa over impacted teeth by subpopulations of macrophages M1 and M2(Aluna Publishing, 2021) Tkachenko, P. I.; Dmytrenko, M. І.; Cholovskyi, M. О.; Korovina, L. D.; Mamontova, T. V.; Ткаченко, Павло Іванович; Дмитренко, Марина Іванівна; Чоловський, Микола Олександрович; Коровіна, Лідія Дмитрівна; Мамонтова, Тетяна ВасилівнаThe aim: Of the study is to research quantitative parameters of mucous membrane macrophages populations M1 (CD68+) and M2 (CD163+) over vestibularly and palatally impacted teeth. Materials and methods: A group of 21 people aged from 10 to 16 years was formed to conduct the research. Clinical situation according to diagnostic criteria was identical in all the patients. The group was divided into two groups - control and experimental, which in their turn were fragmented into two subgroups. Immunohistochemical studies of mucosal biopsies were performed in accordance with the recommendations for selection. Results: Study of ratio of CD68+/CD163+ cells revealed imbalance in individuals with vestibularly impacted teeth due to higher infiltration density of CD163+ (p<0,05), compared to CD68+ of control group. In individuals with palatally impacted teeth, ratio of CD68+/CD163+ increased 3,6 times, as well as compared with control group, but due increased infiltration density of CD68+. Conclusions: In the epithelium of oral mucosa located over impacted teeth, both on vestibular and palatal surface, number of CD 68+ and CD163+ cells had no significant differences compared to control group. In biopsies of the lamina propria of mucosa over vestibularly impacted teeth, the ratio M1/M2=0,91±0,11 (p<0,05) decreases, with predominance of macrophages CD163+ subpopulation activity, and over palatally impacted teeth balance of M1/ M2 macrophages elevated (M1/M2= 2,10 ± 0,32, p<0,05), due to increased infiltration density of CD68+.Документ Incidence and structure of the bening soft tissuetumors of maxillofacial region in children(Національний медичний університет імені О. О. Богомольця, 2019) Tkachenko, P. I.; Bilokon, S. O.; Bilokon, Yu. S.; Dogan, S.; Bieliaiev, I. S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Бєляєв, Ігор СергійовичAccording to the statistical data, children with tumors of the maxillofacial region (MFR) account for 12-22% of all patients with tumors, and 90% fall to the share of benign processes, where mesenchyme-related tumors or, less frequently, epithelial neoplasms, prevail. At the same time, soft tissues tumors of face and neck account for 55-62% among the MFR cancers in children. Tumors in children have specific characteristics, in contrast to adults, and the age changes in metabolism and physiological functions of child body specify possible clinical differences in tumor processes among children of different age groups. Morphologists also highlight a number of features of child tumor processes, regardless of their localization, reminding of the possibility of transformation of some malignant tumors into benign ones. The paper is aimed at representation of our data on the incidence and structure of some nosological forms of benign tumors of head and neck in children. It has been found that in the 10-year period of our observations, the number of children with benign tumors of maxillofacial region accounted for 7,5% of the total number of patients treated in the Surgical Unit of the Poltava Children’s Municipal Clinical Hospital. Among the nosological forms, dermoid cysts (32,7%) and hemangiomas (26,0%) occurred most commonly and the peak of morbidity (25,0%) was observed in infants. In most cases (55,4%) soft tissue benign tumors and tumor masses of maxillofacial region occurred in girls, with more frequent (62,9%) occurrence of hemangiomas, whereas dermoid cysts were more frequently found in boys (61,7%). In 22,4% of the cases, the pathological focus was detected on the neck, in 14,0% on the forehead, in 10,8% in the soft oral tissue, in 7,7% on the lower lip, in 7,7% on the cheek, in 6,2% on the upper lip, and in 3,1% of patients on the chin. In 25,9% of cases, hemangiomas covered several anatomical areas at ones. Recurrences of tumors after surgery have been recorded in 6,7% of patients: in 43,0 % of children it was happened after surgical excision of the middle neck cyst and per 28,5 % of the cases of angiomas and ranulas. The comparative analysis of the clinical diagnosis and postoperative morphological study of the removed tumors has established that in 15,3% of cases the clinical diagnosis was different from the pathohistological one. In most cases it was associated with dermoids (75,0%), fibromas (15,6%) and lymphangiomas (9,4%). Considering the fact that the prognosis for children with abovementioned pathology is determined by the option of histological structure and primary localization of the tumor, the timeliness and adequacy of the treatment activities, implementation of the advanced methods of diagnostics with the high level of awareness is crucial in the improvement of the effectiveness of health care provided for patients of this category, contributing to the correct diagnosis, selection of the treatment procedure and determine the extent of surgical intervention at the preparing period.Документ Insect bites as the cause of infectious and allergic inflammatory processes of the maxillofacial area in children(Wydawnictwo Aluna, Polska, 2019) Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Prylutskyi, O. K.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Vakhnenko, A. V.; Gogol, A. M.; Rezvina, K. Yu.; Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Прилуцький, Олексій Костянтинович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Вахненко, Андрій Вікторович; Гоголь, Андрій Михайлович; Резвіна, Катерина Юріївна; Коротич, Наталія МиколаївнаTo attract attention of the medical community to the problem of the complexity of the diagnosis and treatment of these dermatogenic forms of IP MFA. The work is based on the results of 5 year observations of 42 patients with acute IP MFA arising after insect bites, their comprehensive examination and treatment. 1. IP of MFA, arising as a result of insect bites, is a very urgent problem of pediatric surgical dentistry and require an individual approach in the diagnosis and treatment of patients. 2. A large role in preventing the occurrence of these nosological forms is given to medical workers, a sufficient organization level of sanitary and educational work, and the treatment of such cases becomes a common task of doctors of different profiles. However, much depends on the parents, their level of responsibility and competency, ensuring of timely treatment and provision of qualified medical care to children, preventing the development of severe complications. 3. The issues related to the etiopathogenesis of this pathology require profound scientific research.Документ Optimization of surgical-orthodontic treatment tactics in patients with impacted teeth(Aluna Publishing, 2019) Tkachenko, P. I.; Dmytrenko, M. I.; Cholovskyi, M. O.; Ткаченко, Павло Іванович; Дмитренко, Марина Іванівна; Чоловський, Микола ОлександровичIntroduction. Impacted teeth is complex anomaly of teeth eruption that requires a balanced approach not only in the differential diagnosis of its forms, but choice of rational methods of treatment. The aim of the study. Optimization of the tactics of orthodontic-surgical treatment of patients with impacted teeth based on the development and implementation of computed tomographic indices (KT) and photometric indices (FM) of opening of surgical access (OSA) to crowns of impacted teeth Objects and Methods of research. The results of treatment of 48 patients with delay of permanent teeth eruption have been analyzed. For an objective assessment of treatment results , a group of 24 (aged from 9 to 19 years old ) was formed. All 24 patients had typical clinical situation. Results. Orthodontic correction of patients envisaged, first of all, the elimination of obstacles in the way of teeth eruption, if necessary to provide space in dental arch and simultaneous treatment of associated bite malocclusions. Surgical exposure of impacted tooth crown was carried out and at the same time a triangular shaped guiding channel was formed, base of channel was at the impacted tooth and its angle finished into the dental arch. Precise dimensions and depth of the channel were preliminary planed on computed tomography slices with 3D reconstruction. Mean values of CT width (7,13±0,54mm), and length (6,42±0,78mm) of OSA and CT index (130,79±8,19%) of OSA to impacted teeth crowns were determined. Conclusion. To improve the quality of diagnosis and optimization of methodological approaches to treatment of patients with teeth impaction, we have proposed CT and FM OSA indices to the crowns of impacted teeth. The developed indices serve as specific reference points for optimization of diagnostic process, for reducing of probability of repeated surgical interventions and choosing the optimal path for instrumental orthodontic treatment of patients with impacted teeth.Документ Planning of surgical procedures in complex orthodontic treatment of patients with impacted teeth. Review of treatment methods and two clinical cases(2023) Dmytrenko, M. І.; Tkachenko, P. I.; Smaglyuk, L. V.; Cholovskyi, M. О.; Shaienko, D. P.; Дмитренко, Марина Іванівна; Ткаченко, Павло Іванович; Смаглюк, Любов Вікентіївна; Чоловський, Микола Олександрович; Шаєнко, Дмитро ПавловичTooth impaction is common and complex anomaly of dentition. The approach to treatment of patients with impacted teeth should be comprehensive and to combine surgical treatment, aimed at creating conditions for eruption of impacted teeth and orthodontic movement them into the dental arch. The article presents methods of surgical techniques planning in patients with impacted teeth and demonstrates two clinical cases of treatment with differentiated access to crowns. At their vestibular position, surgical exposure should be carried out with a wide access, and at a palatal one, the access should be limited to sparing. The developed diagnostic and treatment algorithm made it possible to achieve acceleration of bite restoration terms and increase in the effectiveness of stabilization measures in 85% of cases.Документ Provision of urgent assistance to children with traumatic injuries of the soft tissues of the maxillo-facial region(Wydawnictwo Aluna, 2023) Tkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, О. В.; Popelo, Yu. V.; Korotych, N. M.; Rezvina, K. Iu.; Hohol, Ya. A.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Попело, Юлія Вікторівна; Коротич, Наталія Миколаївна; Резвіна, Катерина Юріївна; Гоголь, Андрій МихайловичВид та обсяг лікувальних заходів у дітей з травматичним ушкодженням м’яких тканин в значній мірі залежить від виду і характеру травмуючого агента. Найчастіше дитячому хірургу-стоматологу доводиться мати справу з ранами, які характеризуються порушенням цілісності м’яких тканин і які мають індивідуальні особливості, що слід враховувати при проведенні їх первинної хірургічної обробки та визначені обсягу медичного супроводу в ранньому післяопераційному періоді.