Наукові праці. Кафедра пропедевтики терапевтичної стоматології

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Analysis of the dynamics of functional occlusion indicators in the construction of occlusion surfaces of orthopedic structures
(Aluna, 2020-12) Yarova, S. P.; Turchenenko, S. O.; Tkachenko, I. M.; Yarov, Y. Y.; Ткаченко, Ірина Михайлівна
The aim: Is to evaluate the effectiveness of the proposed method of constructing occlusal surfaces of orthopedic structures by monitoring the dynamics of functional indicators of occlusion and the functional condition of the masticatory muscles. Materials and methods: The object of the study was made up by 64 patients with included defects of the dentition of the 3rd class according to Kennedy. Patients were divided into two equal groups - the main group (patients were treated by using the suggested method of construction of occlusal surfaces of orthopedic structures) and control (dentition defects were replaced according to the traditional protocol). Results: The results of evaluating the effectiveness of the proposed method showed that the index of symmetry of the anterior bundles of the temporal muscles dropped by 18,5%, the index of symmetry of the masticatory muscles reduced by 22%, the torque of the mandible reduced by 32%, the index of stabilizing occlusal - by 27%, relative efforts of balance disturbance for more than 10 % regarding the left and right reduced by a factor of 4.4, the rate of opening time was 1.5 times higher than before, the rate of time of opening of the jaws -1.8 times. Conclusions: The use of the suggested method of orthopedic treatment with temporary structures leads to probable changes in the studied functional parameters in comparison with the control group (p <0,05).
Application of antiseptic and osteoplastic drug for destructive peridontitis treatment
(Aluna, 2019) Lyashenko, L. I.; Lobach, L. M.; Petrushanko, V. M.; Nazarenko, Z. Y.; Tkachenko, I. M.; Ляшенко, Лілія Іванівна; Лобач, Лариса Миколаївна; Петрушанко, Володимир Миколайович; Назаренко, Зоряна Юріївна; Ткаченко, Ірина Михайлівна
Introduction: Treatment of destructive forms of chronic periodontitis is extremely topical. Its relevance is associated with the features of treatment, which depends on the stage of the exacerbation process. The issue of the problem is also in the fact that the destructive seat of periodontitis is a source of chronic infection. The aim:The task of the research was to evaluate the conservative treatment of chronic destructive forms of periodontitis with a dental kit “Cupratin”, developed for professional usage in dental practice. Materials and methods: “Cupratin” is a complex medicament based on suspensions of calcium hydroxide, copper-calcium hydroxide and powder, which contains hydroxide aluminosilicate and calcium sulphate, radiopaque filler. It has bactericidal and osteoplastic effect. The treatment involved 44 patients (44 teeth) in the age group of 37 to 50 years suffering from chronic granulating periodontitis without concomitant diseases. Patients were divided into two groups: investigated and control. In the main group of patients, a suspension on the basis of copper-calcium was used for treatment (root canals were filled with “Cupratin” as a temporary filling material). Obturation of canals was preceded by chemical and mechanical treatment. The medical material was in direct contact with periodontal tissues for 20-55 days. Intraoral X-ray radiography was taken from the patients within the intervals of 3 and 6 months. Results and conclusions: Positive results were obtained, which were characterized by the disappearance of subjective symptoms, intensive bone tissue reconstruction in the site of destruction and a decrease in the size of the destruction respectively.
Applying of chlorine-containing antiseptic extracted from sodium troklosene in complex treatment of chronic generalized parodontitis
(Українська медична стоматологічна академія, 2018) Lyashenko, L. I.; Harkun, A. D.; Nazarenko, Z. Y.; Tkachenko, I. M.; Khmil, E. V.; Ляшенко, Лілія Іванівна; Гаркун, Анна Дмитрівна; Назаренко, Зоряна Юріївна; Ткаченко, Ірина Михайлівна; Хміль, Олена Всеволодівна; Ляшенко, Лилия Ивановна; Гаркун, Анна Дмитриевна; Ткаченко, Ирина Михайловна; Хмиль, Елена Всеволодовна
Генералізований пародонтит (ГП) являє собою актуальну медико-соціальну проблему. Її важливість визначається тим, що число осіб з ГП неухильно зростає, і дана патологія втрачає свої вікові обмеження. За даними ВООЗ, 15-18-річні підлітки в 55-89 % випадків потерпають від гінгівітів або початкової стадії генералізованого пародонтиту. Поширеність генералізованих форм захворювань тканин пародонту серед дорослого населення України за даними різних авторів складає 85-96%. Захворювання пародонту – соціально значима проблема, обумовлена широкою поширеністю і інтенсивністю поразки усіх вікових груп населення. Мікробна флора при пародонтиті різного ступеня тяжкості різноманітна і залежить від ступеня важкості і фази захворювання. На сьогоднішній день перспективним напрямком розробки засобів по догляду за ротовою порожниною є розробки направлені на зниження адгезії мікроорганізмів до поверхні емалі. Метою нашого дослідження було вивчення динаміки змін у мікробіоцинозних асоціаціях при комплексному лікуванні генералізованого пародонтиту при використанні антисептичного препарату «Oral Blue» на основі антисептику «Troklosene»; В данном исследовании нами проанализирована клиническая эффективность препарата «Oral Blue» на основе антисептика «Troklosene» для лечения хронического генерализированного пародонтита II, III степени тяжести у больных без сопутствующей патологии. Динамика клинических и лабораторных показателей, а именно: гигиенического индекса OHI-S Green-Vermillion, пробы Шиллера-Писарева, индекса РМА в модификации С. Parma, КПИ по П. А. Леусу, изменение бактериальной массы и микробного соотношения, сокращение курса лечения свидетельствуют в пользу предложенного нами метода комплексного лечения данной патологии; In this study, we analyzed the clinical effectiveness of the drug “Oral Blue” on the basis of the antiseptic “Troklosene” for the treatment of chronic generalized periodontitis II, III severity in patients without concomitant pathology. The dynamics of clinical and laboratory indicators, namely the hygienic index of OHI-S Green-Vermillion, the Schiller-Pisarev test, the PMA index in the modification of S. Parma, the KPI according to PA Leus, the change in bacterial mass and microbial ratio, In favor of our method of complex treatment of this pathology.
Bruxism as a marker of violation of psychological adaptation in computer game players
(ALUNA Publishing House, 2021-08) Sydorova, A. I.; Lyashenko, L. I.; Pavlenkova, E. V. ; Pavlenko, S. A. ; Lobach, L. M.; Сидорова, Алла Іванівна; Ляшенко, Лілія Іванівна; Павленкова, Олена Вікторівна; Павленко, Світлана Анатоліївна; Лобач, Лариса Миколаївна
To study the relationship between the psycho-emotional state of computer game players with the development of bruxism, its early diagnosis in people at risk, increasing the effectiveness of preventive measures in people with this pathology.
Changes in electromyography test results of patients with pathological abrasion of teeth. The role of anterior teeth in the process of rehabilitation
(Aluna, 2019) Tkachenko, I. M.; Vodoriz, Y. Y.; Marchenko, I. Y.; Shundryk, M. A.; Korol, D. M.; Gurzhiy, O. V.; Ткаченко, Ірина Михайлівна; Водоріз, Ярослав Юрійович; Марченко, Ірина Ярославівна; Шундрик, Марина Аркадіївна; Король, Дмитро Михайлович; Гуржій, Олена Вікторівна
Introduction: Abrasion of teeth significantly affects electromyography results. Analyzing electromyograms of patients who needs complex rehabilitation, it is necessary to note absence of dissociation of the structure, appearance of spontaneous activity in one of the muscles, presence of the prevailing chewing side, appearance of low-amplitude oscillations in biocurrents. The aim: The purpose of this study was to determine the role of anterior teeth in the rehabilitation of patients with increased abrasion. Material and methods: The experimental group involved patients (men and women) aged 20 to 59 years with increased abrasion of teeth I-III degrees. Patients were provided with all the necessary complexes of rehabilitation measures: direct restorations with composite materials using the adhesive system of the Vth generation (in case of light abrasion), indirect ceramic restorations (severe abrasion). All work was conducted in accordance with the Declaration of Helsinki (1964) and was approved by the Ethical Committee of the academy. Results: Activity of the right masseter muscle was slightly higher than that of the left one (313.42 ± 97.96 ms. against 226.69 ± 35.39 ms. respectively). At the same time the resting time of the left and right masseter muscles slightly differs (300.57 ± 30.93 ms. and 307.96 ± 49.47 ms. respectively). Conclusions: Rehabilitation of patients with increased abrasion using combined methods (direct composite restorations with the adhesive system of Vth generation and indirect ceramic restorations), give the possibility to restore the masticatory function (evidenced by an increase in the activity of right and leftmasseter muscle on 2%, a decrease in the rest phase on 20% almost and an increase in amplitude on 2.9%).
Changes in the functional condition of the masticatory muscles with increased teeth abrasion
(Aluna, 2019) Pavlenko, S. A.; Pavlenkova, E. V.; Tkachenko, I. M.; Sidorova, A. I.; Vodoriz, Y. Y.; Samoylenko, A. V.; Павленко, Світлана Анатоліївна; Павленкова, Олена Вікторівна; Ткаченко, Ірина Михайлівна; Сидорова, Алла Іванівна; Водоріз, Ярослав Юрійович; Павленко, Светлана Анатольевна; Павленкова, Елена Викторовна; Ткаченко, Ирина Михайловна; Сидорова, Алла Ивановна; Водорез, Ярослав Юрьевич
Introduction: The term “pathological abrasion” (increased abrasion) can be described as a loss of tooth hard tissue on the occlusal, oral, vestibular surfaces of teeth or in the occlusal area. Treatment of increased abrasion of teeth is a difficult task for the practical work of a dentist. The choice of the optimal treatment plan provides the greatest likelihood of long-term success and minimal probability of complication appearance. The aim of our work was to study the functional activity of the masticatory muscles in the pathogenesis of the development of increased abrasion of tooth hard tissues. Materials and methods: In order to achieve the goal of the study, an examination of patients aged between 19 and 69 years old was carried out in order to identify the number of persons with increased abrasion of teeth. During the examination of all patients one control and one researched group were formed. The patients of the control group (30 patients aged from 18 to 60 years) which had intact dental rows with any signs of increased tooth wear. The investigated group consisted of 25 patients, aged from 18 to 60 years. Depending on the complex treatment, the patients of the second group were divided into two subgroups. Subgroup 2A - (10 patients) with increased abrasion of tooth hard tissues with planned complex treatment of the disease without additional use of mouthguards after the end of treatment. For the patients from the 2B subgroup (15 people with increased abrasion of tooth hard tissues) a mouthguard was prescribed after the end of the complex treatment. In order to study some peculiarities of the muscular activity of the maxillofacial region an electromyogram was taken from all participants before treatment and repeated in a six- and twelve-months term. Results and conclusions: In our opinion, all manifestations of increased tooth abrasion are associated with changes in the muscular system, the motor apparatus and the nervous activity of the body. Regarding to this, the study of the propria muscular system and the related bone system can justify the usage of one or another prevention or treatment of the pathology. Based on the results of our research, we can conclude that the study of the functional state of the muscle complex is a fairly reliable prognostic sign in the study of such a disease as an increased tooth abrasion.
Clinical features of influence of different groups of bleaching agents in the oral cavity at different periods after the end of the treatment
(Полтавський державний медичний університет, 2022) Dvornyk, A. V.; Dvornyk, V. M.; Vodoriz, Y. Y.; Skripnykov, P. M.; Tkachenko, I. M.; Дворник, Анна Валентинівна; Дворник, Валентин Миколайович; Водоріз, Ярослав Юрійович; Скрипников, Петро Миколайович; Ткаченко, Ірина Михайлівна
The purpose of the study was to assess the clinical changes in the oral cavity after using teeth bleaching systems of different compositions. Totally 65 patients were examined. All patients were 20 to 40 years old and had no severe dental and somatic pathology. This clinical study evaluated the effectiveness and side effects of two products for teeth bleaching. The difference in clinical indicators after the bleaching procedure with the selected gels on the microelement structure of oral liquid was detected. We noticed a significant difference in calcium and sodium indices in the oral fluid. Teeth bleaching agents cause tooth sensitivity manifested by changes in the oral fluid viscosity, pH, and the micronutrient composition. Depending on the bleaching agent used, the teeth bleaching procedure should be completed with remineralizing therapy.
Comparative characteristics of the results of professional use of whitening systems “Opalescense boost” and “Magic Smile Pro”
(Полтавський державний медичний університет, 2024) Nazarenko, Z. Y.; Lyashenko, L. I.; Brailko, N. M.; Tkachenko, I. M.; Marchenko, I. Y. ; Назаренко, Зоряна Юріївна; Ляшенко, Лілія Іванівна; Браїлко, Наталія Миколаївна; Ткаченко, Ірина Михайлівна; Марченко, Ірина Ярославівна
The modern rhythm of life dictates its standards to us. One of the standards of the new time is a beautiful smile, and one of the main criteria for a beautiful smile is snow-white teeth without traces of dental plaque, pigments and plaque. The purpose of our study was to determine the comparative clinical effectiveness the use of whitening systems «Opalescence boost» and «Magic Smile Pro» for whitening of the vital teeth and to investigate hyperesthesia as the most common complication of this procedure. We performed in-office teeth whitening in 62 patients aged 25 to 40 years. As a result of the study, we found that the whitening systems «Opalescence Boost PF» and «Magic Smile Pro» have sufficient clinical efficacy, which was more pronounced in the whitening system «Opalescence Boost PF». After using these whitening systems, such a complication as hyperesthesia can rarely occur, the degree and frequency of which is more pronounced when using the «Magic Smile Pro system».
Determination of fractal dimension of the functional masticatory test patterns
(The New Armenian Medical Journal, 2018) Korol, D. M.; Kindiy, D. D.; Toncheva, K. D.; Korol, M. D.; Tkachenko, I. M.; Король, Дмитро Михайлович; Кіндій, Дмитро Данилович; Тончева, Катерина Дмитрівна; Король, Михайло Дмитрович; Ткаченко, Ірина Михайлівна
Valid diagnostic assessment of the state of dentoalveolar system and its masticatory function, in particular, is considered to be an important scientific task of modern prosthodontics. Plenty of the developed ways are based on the use of up-to-date information technology, especially on computer analysis of graphic data. The development of the enhanced methods for the evaluation of masticatory efficiency in patients with both full and partial adentia urged the search of its clear and informative indicators. According to the authors, digital image fractal dimension index can meet these needs. Since most of the available masticatory function assessment methods involve the obtaining large ammount of fragments different in their quantity, size and shape. The photography of the multiplicity of these ‘spasmodically’ located objects allows the processing ofthe received image with the help of graphic editor and converting it into numeric data. Thus, the aim of the research was to study the fractal dimension of the masticatory test images, taking into account the peculiarities of the patients’ denture defects. computer software for digital image processing ImageJ 1.50b was used in the research, since it provides the option of computer calculation of the fractal dimension index. The comparison of the masticatory tests of 30 persons with intact teeth (control group) and 33 persons with denture defects has revealed statistically significant deviation in their fractal dimension index. The reduction of the range of conventional statistical norm (1.49-1.66) to the values fluctuating from 1.47 to 1.51. was observed. Therefore, the decrease of the mean value of the fractal dimension from 1.56 (St.Err.= 0.02) to 1.50 indicates the reduction of chopping function in the given masticatory test patterns. As a result, the suggested method will allow the use of fractal dimension index as an integral indicator of masticatory efficiency level.
Differential drug correction cytokine and prostaglandin content in blood and gingival fluid in generalized periodontitis against the background of different responsiveness of the organization
(Aluna Publishing, 2023-09) Yarov, Yu.; Tkachenko, I.; Skripnikov, P.; Pavlenkova, O.; Pavlenko, S.; Яров, Юрій Юрійович; Ткаченко, Ірина Михайлівна; Скрипников, Петро Миколайович; Павленкова, Олена Вікторівна; Павленко, Світлана Анатоліївна
The aim is to study the dynamics of prostaglandins and cytokines in the blood and gingival fluid against the background of differential drug correction in patients with generalized periodontitis with different body reactivity. Materials and methods: 216 people aged 45 between 55 years with a diagnosis of generalized periodontitis of II, III degree of severity, chronic course were examined. Depending on the state of reactivity of the organism, the patients were divided into three groups: the first one consisted of people with normoreaction; the second group included patients with hyperreaction; the third group was made up of people with hyporeaction. The patients underwent patch surgery after the initial therapy. Initially, on the 1st, 2nd, 4th, 6th and 9th day after the operation, the content of prostaglandins (PG) E, E2, F2alpha and cytokines (IL-1β, IL-6, TNF, IL-4) in the blood and gingival fluid was performed. Patients with impaired body reactivity were treated with the proposed differential drug correction of cytokines and prostaglandins. Statistical processing of the obtained digital data was performed using the computer program Statistica 8.0. Results: The proposed differential drug correction in patients with generalized periodontitis against the background of hyper- and hyporeactivity of the body brings the content of IL-1β, IL-6, TNF, IL-4 to that of normal body reactivity, which ultimately restores the disturbed balance of pro- and anti-inflammatory cytokines in the blood and gingival fluid. On the 9th day, the content of all proinflammatory cytokines in the main groups was normalized and was commensurate with that of the body’s normal response (p>0.05). Differential drug correction led to normalization of the prostaglandin balance index on day 9 after flap surgery (p>0.05), indicating the establishment of a normal balance of eicosanoids in the blood and approximating the values of pro- and anti-inflammatory fractions of prostaglandins to those of normal body reactivity. Conclusion: Correction of altered parameters in patients with generalized periodontitis accompanied by impaired (hyper- and hypo-) reactivity of the body with bringing them to values that are typical for normoreactivity is considered to be a condition for optimizing mucosal wound healing after surgery and further stabilization of periodontal tissues.
Effects of professional oral hygiene and teeth whitening on the microelement composition of enamel
(Aluna Publishing, 2023) Dvornyk, A. V.; Vodoriz, Ya. Y.; Pysarenko, O. A.; Marchenko, I. Y.; Tkachenko, I. M.; Дворник, Анна Валентинівна; Водоріз, Ярослав Юрійович; Писаренко, Олег Анатолійович; Марченко, Ірина Ярославівна; Ткаченко, Ірина Михайлівна
Aim: The objective of this study is to investigate the impact of professional teeth cleaning and the substances used in modern dentistry for whitening on the microelement composition of tooth enamel. Materials and methods: To study the morphology and microelement composition of the enamel, scanning electron microscopy was performed using the MiraLM microscope equipped with a Schottky field emission electron gun from Tescan. Results: A comparative analysis between the areas subjected to mechanical cleaning and those where it was not applied revealed a significant difference in the research results, particularly in carbon, which changed from 25.16±1.04 to 32.02±1.8. An analysis of the enamel’s chemical composition before and after whitening revealed a decrease in carbon from 45.91±1.20 to 42.46±1.74. The change in phosphorus content was determined to be from 9.77±0.39 to 9.56±0.75. A decrease in calcium from 15.96±0.64 to 15.21±1.22 and magnesium from 0.07±0.01 to 0.01±0.01 was also observed. Conclusions: Professional dental hygiene does not have a direct impact on the microelement composition of enamel, such as the levels of calcium, phosphorus, fluoride, and other microelements. However, it can have an indirect and temporary influence due to the use of abrasive materials that affect dental deposits, pellicle, and the surface layer of enamel. Teeth whitening can affect the microelement composition of enamel, but these changes are mostly temporary and associated with processes of demineralization/remineralization and oxygenation.
Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication
(Aluna, 2018) Zolotukhina, O. L.; Romanova, I. G.; Gerasimova, I. V.; Kravchenko, L. S.; Tkachenko, I. M.; Ткаченко, Ірина Михайлівна
Introduction: Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke. Materials and methods: At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Biochemical researches at periodontitis in rats were conducted for determination of influencing stomach pathology and tobacco smoke. On the II stage efficiency of local therapy was studied with the use of the new preparation for oral care and a comparator agent.Results: At experimental periodontitis against a background of hyperpeptic gastritis under conditions of smoking the considerable changes in periodontal tissues typical for the inflammatory process develop. The local therapy at rats with the use of the new preparation resulted in accelerating removing harmful influence of damaging factors and restoring the state of periodontal tissues, than in case of application of the comparator agent. Conclusions: The efficiency of the new preparation consists in normalizing influence on processes of lipid peroxidation, inflammation and activation of the protective systems of oral cavity during periodontitis which arises up against a background of hyperpeptic gastritis.
Evaluation of effectiveness of treatment-and-prophylactic complex in tobacco-addicted patients with chronic generalized periodontitis on the background of chronic hyperacid gastritis
(ALUNA, 2020-12) Zolotukhina, O. L.; Romanova, I. G.; Pyndus, T. O.; Romanov, G. O.; Tkachenko, I. M.; Ткаченко, Ірина Михайлівна
The aim: To evaluate the clinical efficacy oftreatment-and-prophylactic complex in patients addicted to tobacco with chronic gen era Iced periodontitis with chronic hyperacid gastritis. Materials and methods: 68 patients (men and women) aged 25-44 years were examined. They were distributed into two groups: the main group—48 patients addicted to tobacco with chronic generalized 1 degree periodontitis and chronic hyperacid gastritis, associated with Helicobacter pylori, the control group—20 healthy individuals without bad habits. Patients of the main group were distributed at random into 2 subgroups (1.1,1.2) depending on the chosen therapy. The patients of the subgroup 1.1 received the basic therapy and the developed treatment and prophylactic complex, the subgroup 1.2 received the basic therapy and the ultraphonophoresis procedures with placebo. Assessment of the effectiveness of therapy was carried out by detennining hygienic index OHI-S and periodontal indices (PI, PMA index and Muhlemann bleeding index (MBI)). Results: The usage of the treatment-and-prophylactic complex resulted in improvement of the hygienic index OHI-S and periodontal indices (PI, PMA index and MBI) at the immediate and late observation period. Conclusions: Results of the study confirmed the effectiveness of the proposed treatment-and-prophylactic complex in therapy of chronic generalized 1 degree periodontitis in patients addicted to tobacco smoking with chronic hyperacid gastritis.
Experimental study of changes in the chemical composition of tooth enamel when using hydrogen peroxide as the main chemical component in professional bleaching
(Aluna Publishing, 2022) Dvornyk, A. V.; Tkachenko, I. M.; Pysarenko, O. A.; Vodoriz, Y. Y.; Dvornyk, V. M.; Brailko, N. M.; Дворник, Анна Валентинівна; Ткаченко, Ірина Михайлівна; Писаренко, Олег Анатолійович; Водоріз, Ярослав Юрійович; Браїлко, Наталія Миколаївна; Дворник, Валентин Миколайович
Objective: The aim: To study changes in the chemical composition of the tooth enamel surface when using hydrogen peroxide as a chemical component of the whitening system in combination with professional oral hygiene. Patients and methods: Materials and methods: To achieve this goal, during the study, we studied the enamel of the teeth of the frontal area, which was removed for orthodontic and orthopedic indications. The age of the patients whose teeth were examined ranged from 18 to 44 years. In the experiment, we studied the chemical structure of enamel by a method thatcovered the selection of the study area, with the designation of areas for microanalysis, and subsequent elemental analysis in selected areas of the enamel. Results: Results and conclusions: Analyzing the results of this study, we can make assumptions about the impact of professional dental hygiene on the procedure of photo-whitening teeth based on 35% hydrogen peroxide gel and its subsequent impact on theother clinical indicators, which will depend on the characteristics of functional and structural resistance of the enamel.
Impact of migration on health and mortality
(Полтавський державний медичний університет, 2024) Lyashenko, L. I.; Nazarenko, Z. Y.; Tkachenko, I. M.; Chyzhevska, M. B.; Brailko, N. M.; Ляшенко, Лілія Іванівна; Назаренко, Зоряна Юріївна; Ткаченко, Ірина Михайлівна; Чижевська, М. Б.; Браїлко, Наталія Миколаївна
The survey showed that theconditions in which migrant workers worked in construction and agricultural work ofted did not meet sanitary and hygienic requirements and safety rules, which increased the risk of occupational injuries.
Index assessment of periodontal status in patients on the background of administering a drug with circadian activity
(Aluna publishing, 2024-07) Vasko, M. Yu.; Tkachenko, I. M.; Vodoriz, Ya. Yu.; Dvornyk, A. V.; Pysarenko, Oleh A.; Васько, Марина Юріївна; Ткаченко, Ірина Михайлівна; Водоріз, Ярослав Юрійович; Дворник, Анна Валентинівна; Писаренко, Олег Анатолійович
Objective: Aim: The aim of this study was to determine the effect of application of drug with circadian activity (pioglitazone) for treatment of patients with periodontist. Patients and methods: Materials and Methods: Group I - 18 individuals with healthy periodontium. Group II - 12 participants with stage II, grade B periodontitis treated with a standard treatment protocol. Group III - 12 participants with stage II, grade B periodontitis, treated with a regimen that included the standard protocol along with the administration of pioglitazone prescribed at recommended times of intake. Group IV - 12 participants with stage II, grade B periodontitis treated with the standard protocol and pioglitazone against the recommended intake hours. Results: Results: The Simplified Oral Hygiene Index in Group I was 0.406±0.034. In Group II, it was 2.5±0.06. In Group III, the hygiene index was 2.633±0.056 and in Group IV it was 2.5±0.059. The Papillary-Marginal-Alveolar Index in Group I was 0.033±0.004. In Group II, it was 0.366±0.011. For Group III, the PMA index was 0.38±0.012 and for Group IV it was 0.378±0.01. The Russell's Periodontal Index in Group I was 0.111±0.008. In Group II, it was 4.668±0.155. For Group III - 4.708±0.132 and for Group IV it was 4.575±0.089. The Gingival Bleeding Index (GBI) in Group I was 0.031±0.003, while in Group II, it was 0.266±0.009, in Group III, it was 0.273±0.007 and in Group IV it was 0.278±0.006. Conclusion: Conclusions: The administration of pioglitazone (the drug with circadian activity) according to its circadian stage indeed has a positive effect on the periodontal status changes of patients with stage II, grade B periodontitis.
Investigation of stress-strain state of "restoration & tooth" system in wedge-shaped defects by computed modeling method
(Aluna Publishing, 2021) Brailko N. M.; Tkachenko I. M.; Kovalenko V. V.; Lemeshko A. V.; Fenko A. G.; Kozak R. V.; Kalashnikov D. V.; Браїлко, Наталія Миколаївна; Ткаченко, Ірина Михайлівна; Коваленко, Віктор Вікторович; Лемешко, Анна Валентинівна; Фенко, Олексій Георгійович; Козак, Руслан Васильович; Калашніков, Дмитро Вікторович
ABSTRACT The aim of this research is to study the influence of size and location of wedge-shaped defects of teeth on stress and strain state of restorative material on the basis of biomechanical analysis. Materials and methods: Biomechanical analysis of the stress-strain state was performed on a jaw bone fragment with canine and premolar inclusion. Results: Tangential stress increase both in the adhesive layer and in restorative material with depth and width (medial-distal size) of restored wedge-shaped defects of teeth,. The most unfavorable loading on a tooth is a joint action of vertical and horizontal loading in lingual- vestibular or vestibular-lingual direction, depending on localization of the restored wedge-shaped defects of teeth. The formation of retention grooves in wedge-shaped defects of teeth reduces the value of the maximum tangential stress in the adhesive layer of restorative material to 25% and extends the longevity of restorations. Conclusions: The difference in maximal values of tangential stress increases in adhesive layer of restorative material with or without retention grooves with increasing depth of defect. Thus, it is advisable to form retention grooves in cases of wedge-shaped teeth defects that exceed 1.5 mm. In case of restoration of subgingival wedge-shaped defects of teeth of small height it is recommended to create one retention groove on the gingival or incisal planes of a carious cavity due to significant inconveniences, and sometimes impossibility of formation of traditionally located retention grooves.
Laboratory methods of research of adhesive systems
(Aluna Publishing, 2020-08) Brailko, N. M.; Tkachenko, I. M.; Kovalenko, V. V.; Nazarenko, Z. Y.; Lemeshko, A. V.; Zelinska, A. B.; Браїлко, Наталія Миколаївна; Ткаченко, Ірина Михайлівна; Коваленко, Віктор Вікторович; Назаренко, Зоряна Юріївна; Лемешко, Анна Валентинівна
The aim of our research was to determine the effectiveness of the sealing property of adhesive systems V and VII generations by studying the depth of curing, water absorption and water solubility of their samples. Materials and methods:The study was performed according to ISO / TS 11405: 2015 at the Central Factory Laboratory of JSC “CTOMA”, Kharkiv, Ukraine, Certificate of Attestation No. 100-062 / 2015 dated 03/04/2015. For the study we used specially prepared laboratory samples which were made in the form of plates from adhesive system “DC Adhesive NF” (Dental Central) of V generation “Single bond Universal” (3M ESPE) of VII generation. А monitor and analyze the results obtained used micrometer MK-25, №4694, №03 / 5321 from 08/18/17; caliper SC-1, No. 267447, No. 03/5322 from 08/18/17; scales AP 210, №112144137, №87027 / 9 from 24.11.2017 Results: According to the results of the investigation the following results were obtained: 1) the average curing depth of V and VII generation of adhesive systems was 4.08mm and 3.51mm respectively at the rate of 2mm; 2) average water absorption: 45.97 µg/mm3 and 30.89 µg/mm3 for V and VII generations respectively; 3) the average water solubility was 6.94 µg / mm3 and 4.17 µg / mm3, respectively. Conclusions: According to the results of our laboratory studies, it can be concluded that adhesive systems of V and VII generations can be used for restoration of lesions of tooth hard tissued. Along with this, it can be recommended to use V generation adhesives in closed defects where direct polymerization should be performed and oral fluid access is minimal. Adhesive sysyems of VII generation can be recommended in such cases as: opened restorations, pregingival areas of teeth, cases where a permanent contact of restorations with oral fluid be found along with the cases of autonomic application of adhesive system.
«Lege artis» у практичній підготовці майбутніх стоматологів
(Тернопольский государственный медицинский университет имени И. Я. Горбачевского, 2015) Марченко, Ірина Ярославівна; Ткаченко, Ірина Михайлівна; Шундрик, Марина Аркадіївна; Назаренко, Зоряна Юріївна; Браїлко, Наталія Миколаївна
Підвищити якість підготовки стоматологічних кадрів можна шляхом удосконалення практичних навиків та вмінь студентів за всіма правилами мистецтва "lege artis". Розглянуто особливості викладання пропедевтики терапевтичної стоматології з удосконаленням мануальних навичок в галузі моделювання зубів, препаруваня та реставрації.
Odontogenic keratocysts of the jaws in children: peculiarities of the clinical and X-ray picture
(Ektodermal Displazi Grubu, 2025) Gurzhii, O. V.; Kolomiiets, S. V.; Skripnikova, T. P.; Tkachenko, I. M.; Гуржій, Олена Вікторівна; Коломієць, Світлана Веніамінівна; Скрипнікова, Таїса Петрівна; Ткаченко, Ірина Михайлівна
The slow growth and asymptomatic course of odontogenic keratocysts of the jaws in children complicates diagnosing on the early stages of development, they have relatively aggressive course and a high rate of recurrence and only when the cyst is large enough the symptoms may appear in the form of jaw deformation, disruption of teeth eruption or changes in their positioning. The purpose of our study is to determine the characteristic features of the clinical and radiological manifestation of keratocysts in the jawbones of children in the period of temporary and permanent occlusion. Clinical material was based on the examination of 8 children aged from 8 to 18 years old suffering from keratocysts of the jaws, who addressed to the clinical base of the Department of Postgraduate Education of Dentists at Poltava State Medical University (Ukraine) lover six years. All children underwent standard X-ray examination: orthopantomogram, computed tomography. Keratocysts were most often detected at age of 12–14 years old. The lower jaw was damaged by the pathological process almost twice as often as the upper jaw. As a rule, the localization of the lesion was in the area of the angle and branch of the lower jaw. And, as for the frontal group of teeth - on the upper jaw. There is a characteristic feature in growth of odontogenic keratocysts - they spread along the length of the jaw and do not cause a pronounced deformation of the bone for a long time; in children, during the period of intensive growth of the jaws, they often have a large size of 3 cm or more. In the period of transitional dentition, we took into account the terms of permanent teeth eruption along with the degree of resorption of the roots of temporary teeth in accordance with the age of the child. We consider the fact that the size of the lesion depends on the age of the child to be a specific feature of the clinical course of keratocysts in children. In case when the process was localized on the upper jaw, we identified the area of destruction of bone tissue with clear rounded contours or of triangular shape in the form of one-chamber cavity in the area of incisors, canines or premolars. The permanent teeth buds were often situated horizontally or pushed distally, some of them were located in the cavity of the cyst. The roots of erupted permanent teeth were turned into the cyst cavity. When the lesion was localized on the lower jaw, the X-ray revealed areas of bone thinning with clear contours, which either spread to the frontal part, or to the body, angle and branch of the lower jaw, the 8th tooth's bud was more often pushed to the branch of the lower jaw. The contours of the periodontal cleft of the teeth, which were located in the area of keratocysts, were always preserved, pathological root resorption was not observed. The growth of the jawbones, anatomic and topographic features of the teeth and jaws in temporary occlusion, immature roots of permanent teeth contribute to the specific course of keratocysts in children. In order to make proper OKC diagnosis, a special place, in addition to anamnesis, should be given to the correct clinical and radiological diagnosing by the means of CT scanning.

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