The role of secreting function of decidua in the development of complications of gestation process in pregnant women with a past history of chronic endometritis
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Дата
2020-11
Назва журналу
Номер ISSN
Назва тому
Видавець
Aluna Publishing
Анотація
The aim: TodeterminetheserumFAMG in theIandII trimesterofpregnancyinwomenwith apast historyofchronicendometritis, andtoclarifyitsimpacton the development
of pathology of pregnancy.
Materials and methods: The level of FAMG was determined at 6-8 and 16-18 weeks of gestation in 135 pregnant women with a past history of chronic endometritis, who
received treatment of chronic endometritis at the stage of pregravid preparation and 168 women who became pregnant without its prior treatment. The dependence of the
development of pre-eclampsia on the level of FAMG at the early stages of pregnancy has been evaluated.
Results: At 6-8 weeks of pregnancy, the level of FAMG in women with a past history of chronicendometritis was 20.6% lower (122.4 ± 7.6 ng/ml) compared to the control
group. In FAMG of 90.3 ± 4.3 ng/ml at 6-8 weeks of gestation, spontaneous abortion occurred in 100% of cases within the next 2 weeks. FAMG lower than 122,1 ± 3,0 ng/ml
can be the predisposing factor for the development of pre-eclampsia.
Conclusions: Reduced FAMG in thebeginning of pregnancy in women with untreatedchronicendometritis in the past history increases theincidenceof miscarriagesat the
earlystages by 2.6 times, andby 1.8 times theprobabilityofpreeclampsiadevelopment. Treatmentofchronicendometritis at thestage of pregravidpreparation promotes the
increaseof FAMG by 24,6% compared to untreated women that reduces theprobabilityof complications during the subsequent course of pregnancy.
Опис
Ключові слова
chronicendometritis, pre-eclampsia, fertility α2-microglobulin, habitual noncarrying of pregnancy
Бібліографічний опис
The role of secreting function of decidua in the development of complications of gestation process in pregnant women with a past history of chronic endometritis / O. O. Taranovska, V. K. Likhachov, L. M. Dobrovolska, O. G. Makarov, Ya. V. Shymanska // Wiadomości Lekarskie. – 2021. – Vol. LXXIII, issue 11. – Р. 2416–2420.