Precision genome editing with CRISPR-Cas9: a gateway to personalized medicine

Abstract

In recent years, clustered regularly interspaced palindromic repeats (CRISPR)-Cas9-derived editing tools have emerged as a transformative force in genome manipulation. These tools, guided by small RNA molecules, have revolutionized our ability to precisely modify the genetic code, offering unprecedented opportunities for both basic research and clinical applications, particularly in gene therapy.