Decamethoxin and chlorhexidine bigluconate effect on the adhesive and biofilm-forming properties of Streptococcus mitis
Ескіз недоступний
Дата
2023-11
Назва журналу
Номер ISSN
Назва тому
Видавець
Frontiers Media SA
Анотація
The aim of the study: Was to investigate the effect of antiseptics on the adhesive
and biofilm-forming properties of clinical S.mitis isolates isolated from the oral
cavity of patients with an infectious and inflammatory post-extraction
complication.
Materials and methods: Twenty four clinical isolates of S.mitis isolated from
patients were studied. The studied antiseptics included 0.02% aqueous solution
of decamethoxin and 0.05% solution of chlorhexidine bigluconate. Adhesion of
clinical isolates under the action of decamethoxin and chlorhexidine
bigluconate was determined by the method of V.I. Brillis. The biofilm-forming
properties of clinical isolates were studied using the “microtiter plate test”
according to G.D. Christensen.
Results: The studied clinical isolates of S.mitis are classified as highly adherent
microorganisms. Action of decamethoxin on clinical isolates decreases the
adhesion index of the studied isolates in comparison with the adhesion index of
the control culture. Action of chlorhexidine bigluconate on S.mitis isolates
increases of adhession of the studied clinical isolates in comparison with the
control. After the effect of decamethoxin, the optical density of clinical isolates
decreased considering the optical density results of the control. The clinical
isolates left an average film-forming capacity even after chlorhexidine
bigluconate action.
Conclusions: Clinical isolates of S.mitis are highly adherent microorganisms. The
antiseptic decamethoxin decreases the adhesion index of these bacteria, while
chlorhexidine bigluconate increases the adhesion index of clinical S.mitis
isolates. Clinical S. mitis isolates have an average biofilm formation capacity
index. The antiseptic decamethoxin inhibits the biofilm formation capacity of
S.mitis from medium to low.
Опис
Ключові слова
infectious complication, post-extraction complication, oral microbiota, antiseptics, biofilm
Бібліографічний опис
Decamethoxin and chlorhexidine bigluconate effect on the adhesive and biofilm-forming properties of Streptococcus mitis / M. O. Faustova, Yu. V. Chuma, G. A. Loban’ [et.al.] // Front. Oral. Health. – 2023. – Vоl. 4. – P. 1268676. doi:10.3389/froh.2023.1268676