Efficacy of long-acting penicillins in combination with doxycycline in the treatment of early stage syphilis

Abstract

During a comparative analysis of the dynamics of KSR negation in the main group of patients who received benzytinbenzylpenicillin in combination with doxycycline, and the comparison group who received the sodium salt of benzylpenicillin, no significant differences were found (Figs. 1-3). This testifies to the approximately equal effectiveness of both methods during the treatment of early forms of active syphilis. Thus, in patients who were treated with benzathine benzylpenicillin in combination with doxycycline, the negation of the complex of serological reactions to syphilis occurred faster compared to patients who were treated only with benzathine benzylpenicillin. This testifies to the favorable long-term results of the method being studied and its high effectiveness for medicine treatment of early syphilis. The method is easy to use and can be recommended for outpatient treatment.