Morphological and functional state of the adrenal glands of rats in normal conditions and changes in the diameters of the cortical substance and medulla after exposure of a food additive complex

Abstract

It was established that the use of food additives (monosodium glutamate, sodium nitrite and Ponceau 4R) directly affects the cortex and medulla of the adrenal glands, causing hypertrophy and perivascular edema in the early stages ofthe experimental study, the reversibility ofthe processes within 8-10 weeks oftaking food additives and irreversibility with alteration of cells and destructive changes of endocrinocytes starting from the 16th week of experimental studies.