Morphometric characteristic of microcircular rate of salivary glands after administration of platyphyllinum and proserinum

Abstract

Salivary glands are important organs, which ensure oral cavity homeostasis. In contemporary clinical practice treatment of salivary dysfunction, in most cases, is limited due to the lack of evidence as for increase in salivation due to drugs that are taken to stimulate the salivary secretion. The purpose of the research was to estimate changes in metric values and capacitive levels of blood microcirculation of the salivary glands under the effect of Platyphyllinum and Proserinum. Morphometric study showed that administration of Platyphyllinum and Proserinum to experimental animals causes similar changes in metabolic and capacitive components of blood microcirculation stream of salivary glands. They are manifested through the increased rates mostly in administration of Proserinum. Microvessels of submandibular gland were the most dilated; the least dilated were microvessels of the parotid gland. The specific feature of hemomicrovessels of sublingual gland was the absence of significant difference between the rates in experimental groups of animals.