Please use this identifier to cite or link to this item:
http://repository.pdmu.edu.ua/handle/123456789/7875| Title: | Quercetin reduces the transcriptional activity of NF-kB in stable coronary artery disease |
| Authors: | Chekalina, N. Burmak, Y. Petrov, Ye. Borisova, Z. Manusha, Y. Kazakov, Yu. Kaidashev, I. P. Кайдашев, Ігор Петрович Чекаліна, Наталія Ігорівна Бурмак, Юрій Григорович Петров, Євген Євгенович Борисова, Зінаїда Олексіївна Мануша, Юлія Іванівна Казаков, Юрій Михайлович |
| Issue Date: | 2018 |
| Publisher: | Higher State Educational Establishment of Ukraine “Ukrainian Medical Stomatological Academy”, Str. Shevchenka, 23, 36000, Poltava, Ukraine |
| Citation: | Quercetin reduces the transcriptional activity of NF-kB in stable coronary artery disease [Electronic resource] / N. Chekalina, Yu. Burmak, Ye. Petrov [et al.] // Indian Heart Journal. – 2018. – V. 70, Issue 5. – P. 593–597. – URL: https://doi.org/10.1016/j.ihj.2018.04.006 |
| Abstract: | The aim of this study was to determine the effect of quercetin on the indicators of chronic systemic inflammation (CSI) in stable coronary artery disease (CAD). Methods: This study included 85 patients with CAD, stable angina pectoris, functional class (FC) II, and heart failure (=F) 0-y. Each patient was prescribed beta-blockers, statins, and aspirin. In addition, a total of 30 patients, forming the study group received quercetin at a daily dose of 120 mg for two months, while the remaining 55 patients made up the control group. The levels of cytokines, such as tumor necrosis factor (TNF-a), interleukin-1b (IL-1b), and interleukin-10 (IL-10) in serum and the expression of the inhibitor of kappa B a (IkBa) gene in blood mononuclear cells, were determined. |
| Keywords: | Coronary artery disease Quercetin Chronic systemic inflammation Cytokines Nuclear factor of transcription kappa B |
| ISSN: | 0019-4832 |
| URI: | http://repository.pdmu.edu.ua/handle/123456789/7875 |
| Appears in Collections: | Наукові праці. Кафедра пропедевтики внутрішньої медицини |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Quercetin_reduces_the_transcriptional_activity .pdf | 396,47 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.