Вісник проблем біології і медицини, 2023, Випуск 2 (169)

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https://repository.pdmu.edu.ua/handle/123456789/21326

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Перегляд Вісник проблем біології і медицини, 2023, Випуск 2 (169) за Автор "Isakov, R. I."

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    Peculiarities of clinico-psychopathological manifestations and sleep quality in patients with anxiety disorders depending on the level of stress load
    (Полтавський державний медичний університет, 2023) Zhyvotovska, A. I.; Isakov, R. I.; Животовська, Анастасія Ігорівна; Ісаков, Рустам Ісроїлович
    Modern scientific studies indicate a close connection between psychological distress, anxiety and impaired sleep quality. The assessment of psychopathological symptoms and components of sleep disorders in 81 patients with anxiety disorders of neurotic origin was carried out using clinical-psychopathological, psychodiagnostic and statistical methods. The psychodiagnostic method included the use of the Psychological stress measure (PSM-25), the Symptom Check List-90-Revised (SCL-90-R) and the Pittsburgh Sleep Quality Index (PSQI). All respondents, depending on the level of psychological stress, were divided into 3 groups, representative by age and gender: 1st group (n=25) – patients with a low level of stress, 2nd group (n=29) – with an average level, 3rd group (n=27) – with a high level of stress. In patients of group 1, indicators on all scales of the SCL-90-R questionnaire were significantly lower than in group 2 (p<0,05) and group 3 (p<0,01). Significant differences were found between group 1 and groups 2 and 3 on the PSQI total score and on the scales of subjective sleep quality, sleep latency, sleep duration, and sleep efficiency. Significantly higher indicators were found in group 3 compared to group 1 on the daily dysfunction scale. The severity of obsessive-compulsive symptoms, additional symptoms, hostility, interpersonal sensitivity, and phobic anxiety had a positive correlation with deterioration in sleep duration, subjective sleep quality, sleep efficiency, sleep latency, and daytime dysfunction according to the PSQI (p<0,01). Disturbances during sleep were positively correlated (p<0,01) with the somatization index. The obtained data should be taken into account when conducting personalized pharmacotherapy and psychocorrection of this cohort of patients.