Наукові праці. Кафедра мікробіології, вірусології та імунології
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Перегляд Наукові праці. Кафедра мікробіології, вірусології та імунології за Автор "Avetikov, D. S."
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Документ Comparison of the effect of antiseptics based on Decamethoxine, Chlorhexidine bigluconate and Iodophorm on the adhesive potential of bacteria of the genus Kocuria spp(2022) Лобань, Галина Андріївна; Фаустова, Марія Олексіївна; Чумак, Юлія Вікторівна; Ананьєва, Майя Миколаївна; Гаврильєв, Віктор Миколайович ; Аветіков, Давид Соломонович; Стебловський, Дмитро Валерійович; Loban', G. A.; Faustova, M. O.; Chumak, Yu. V.; Avetikov, D. S.; Ananieva, M. M.; Gavriliev, V. M.; Steblovskiy, D. V.Antiseptics can block the adhesion of bacteria, thus facilitating the course of the purulent-inflammatory process. Therefore, we investigated the adhesive properties of clinical isolates of the genus Kocuria isolated from the oral cavity of patients with infectious-inflammatory post-extraction complications. Remedies based on decamethoxine, chlorhexidine bigluconate and iodoform were used as test antiseptics. The adhesive properties of clinical isolates under the action of remedies based on decamethoxine, chlorhexidine bigluconate and iodoform were determined by V.I. Brillis. The adhesion index values of microorganisms of clinical isolates of the genus Kocuria under the action of subbacteriostatic concentration of remedy based on decamethoxine were 1.6 times (p<0.05) and 2.1 times (p<0.05) lower compared to those of the adhesion index of microorganisms after the action of remedies based on chlorhexidine bigluconate subbacteriostatic concentrations and iodoform respectively. In the presence of remedy based on chlorhexidine bigluconate SBsC, relative to the clinical isolates Kocuria kristinae 1 and Kocuria kristinae 2, IAM indices increased 1. 3 times, and IAM indices of Kocuria rosea increased 1.1 times compared to the IAM indices of the controls of these isolates. Considering the results of action remedy based on iodoform SBsC on clinical isolates Kocuria kristinae 1 and Kocuria kristinae 2, IAM increased in 2.1 times and in 1.5 times, IAM of clinical isolate Kocuria rosea also increased, but in 1.4 times, considering the control cultures.Документ Sensitivity of causative agents of infectious-inflammatory diseases in maxillofacial soft tissues to antibiotics(Полтавський державний медичний університет, 2023-11) Faustova, M. O.; Nazarchuk, O. A.; Loban’, G. A.; Chumak, Yu. V.; Avetikov, D. S.; Фаустова, Марія Олексіївна; Назарчук, Олександр Адамович; Лобань, Галина Андріївна; Чумак, Юлія Вікторівна; Аветіков, Давид СоломоновичThe aim of the work was to investigate the sensitivity of pathogens of infectious and inflammatory soft tissue diseases in the maxillofacial region to antibiotics. Methods: The 282 clinical isolates obtained from patients were the objects of the study. The sensitivity of the studied microorganisms to antibiotics was determined according to the EUCAST committee quality control standards. Results: The variability in the sensitivity of microorganisms isolated in infectious and inflammatory diseases of the maxillofacial soft tissues to antibiotics has been established. Representatives of the genus Staphylococcus exhibit high sensitivity to vancomycin, fluoroquinolones and lincosamides. At the same time, they are characterized by the lowest sensitivity to aminglicosites and penicillins. Enterococcus spp. have high sensitivity to tetracyclines and fluoroquinolones, showing the lowest results with penicillins and carbapenems. Streptococcuss spp. viridans-group exhibit low sensitivity to penicillins, carbapenems, fluoroquinolones, and lincosamides, while maintaining high sensitivity to glycopeptides. Low sensitivity of Acinetobacter spp. isolated from patients with infectious and inflammatory diseases of maxillofacial soft tissues to antibacterial drugs of different groups was established. Conclusions: The variability in the sensitivity of isolates to antibiotics most commonly used in clinical practice and recommended by the EUCAST quality committee was established, what provides prospects in their use.Документ The profile of specific antibodies to SARS-CoV-2 in residents of the central and eastern regions of Ukraine(Полтавський державний медичний університет, 2022) Avetikov, D. S.; Ananieva, М. М.; Loban, G. A.; Faustova, M. O.; Skikevych, M. G.; Chumak, Yu. V.; Ivanytska, O. S.; Аветіков, Давид Соломонович; Ананьєва, Майя Миколаївна; Лобань, Галина Андріївна; Фаустова, Марія Олексіївна; Скікевич, Маргарита Георгіївна; Чумак, Юлія Вікторівна; Іваницька, Олена СергіївнаDetermination of the level of antibodies in individuals living in certain regions provides insight into the epidemiology of the infection and is crucial for the development of strategies to reduce the spread of COVID-19. The study analyzed the results of IgM and IgG tests for the SARS-CoV-2 virus in 7142 residents of eastern and central regions of Ukraine from July 2020 to January 2021. Patients' visits to COVID-19 for IgM and IgG mainly occurred in the autumn-winter period of 2020–2021, confirming the seasonality of the disease. The most popular test among residents of Poltava and Donetsk regions was the test for IgM immunoglobulins, and the vast majority of results were negative. As of January 2021, the number of people who had IgG antibodies to the pathogen COVID-19, among those surveyed approached 50 % in both Poltava and Donetsk regions