Перегляд за Автор "Assali, Y."

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    Hemoglobinopathies types and their peculiarities in Morocco
    (Полтавський державний медичний університет, 2025) Baidi, A.; Bourtal, Y.; Assali, Y.; Maatof, Ou.; Tkachenko, O.; Ткаченко, Олена Вікторівна; Tkachenko, O.
    There are two forms of thalassemia – alpha- and beta-, though clinically thalassemia is divided into minor, intermediate and major. Beta-thalassemia rate is 6-7% in Morocco (S.S. Khandker, 2023) with prevalence in Casablanca 5% among all cities (S. El Kababi, 2019), alpha-thalassemia 0,96%, particularly in the North (A.Laghmich et al., 2019), minor form 1,2% in a whole country. Carriers rate is 6,5% on beta-thalassemia (N.Marzouki, 2022), alpha-thalassemia 0,30% (I.Belmokhtar et al., 2025) and 8% on both thalassemia types (A.Laghmich et al., 2019). Morocco East became thalassemia region after its North and West (I.Belmokhtar et al., 2022). In Rabat, there was a research set which results demonstrated beta-thalassemia major dependence on HLA antigens of both I and II class (S. Ouadghiri et al., 2024). Novel beta-thalassemia variants (C6(-G) and -83(A>G) as well as Hb structural variant D-Ouled Rabah have been discovered first in Morocco. Beta-thalassemia represents the most widely-distributed hemoglobinopathy in Morocco while hemoglobinosis C takes the second position, alpha-thalassemia the third, hemoglobinosis G-Philadelphia - the fourth, D-Ouled Rabah and O-Arab the fifth one (I.Belmokhtar et al., 2025). Morocco has hemoglobinosis C representing mutant Hb with glutaminic acid replacement into lysine in its beta-chain 6 th position. Moroccan people have not only softer heterozygous form with no anemy but also harder homozygous form with moderate hemolytic anemy and Hb crystals in blood smears. Hemoglobinosis C is distributed in Southern Morocco at a greater extent (N.Marzouki, 2022). A combination between these Hb types represents more difficult pathological condition by course than separate hemoglobinoses. There are the data according to which beta-thalassemia can be in a complex with hemoglobinoses C and S with especially hard form of the disease, met in Eastern Morocco mainly (I.Belmokhtar, 2022), except Southern part of the country. Northern Moroccan city Kenitra is distinguished by sickle cell syndromes or hemoglobinosis S in children. Sickle-cell anemy carriers rate is 6,5% and morbidity 80% in the North and 10,5% in other parts of the country (N.Marzouki, 2022).
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    Morbidity some gender aspects in Morocco
    (Kharkiv National Medical University, 2025) Tkachenko, O. V.; Assali, Y.; Bourtal, Y.; Baidi, A.; Darkouch, A.; Chentir, W.; El Yaagoubi, El Y.; Ткаченко, Олена Вікторівна
    This article is dedicated to morbidity gender typological aspects some peculiarities in Morocco taking into account also ethnic typological aspect, particularly urbanization, concerning to inflectional diseases, cancer, atherosclerosis, metabolic syndrome, arterial hypertension, ischemic heart disease including stenocardia, myocardial infarction, cardiosclerosis post-atherosclerotic as well as diabetes mellitus, the kidneys and sense organs diseases, strokes. The authors differentiate “male diseases” and “female diseases”.
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    Smoking unfavorable action to human organism
    (Полтавський національний педагогічний університет ім В.Г.Короленка, 2024) Tkachenko, O.; Bourtal, Y.; Assali, Y.; Baidi, A.; Ткаченко, Олена Вікторівна
    The article is dedicated to smoking unfavorable action to human organism while paying attention not only to known effects on respiratory system but to its influence on cardiac-vascular system, parodont, oral microflora, vision. The authors emphasize to the fact about smoking teratogenic action, impacts on Alzheimer’s disease and tumors development and progression. It was mentioned that passive smoking of the adults and moreover babies and children was found to be more dangerous than the active one. The authors wrote about electronic cigarettes bigger harm onto the organism than the usual ones because of oncogenes such as benzpyrenes.
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    Thrombocytopenias and thrombocytopathies distinguishing features in Morocco while typological aspects taking into consideration
    (Vinnytsia National Pirogov Memorial Medical University, 2025) Maatof, O.; Mustafa, H.; Bourtal, Y.; Assali, Y.; Tkachenko, О. V.; Ткаченко, Олена Вікторівна
    Disturbances in morphological-functional thrombocytic indices are met rather often in Morocco. The disorders can be primary or hereditary and secondary or acquired as well as quantitative and qualitative. The authors analyzed ethnic, ethnic-gender, ethnic-age and ethnic-gender-age typological aspects contribution in platelets’ structural-functional peculiarities in the Moroccans. They paid attention to thrombocytopenias and thrombocytopathies peculiarities in Morocco taking typological aspects into consideration. Materials and methods: A literary review of scientific sources for 2020-2025 concerning to platelets pathologies in Morocco. Quantitative (Willebrand disease, congenital amegakaryocytic thrombocytopenia, platelets’ integrin receptors anomalies, constitutional thrombocytopeny, idiopathic thrombocytopeny, immune thrombocytopeny) and qualitative problems (Glanzmann thrombasthenia) with platelets were found to be representing serious health issues in Morocco with significant positive correlation of their development to typological aspects.
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    Typological aspects contribution into morbidity patterns in Morocco
    (Ivano-Frankivsk National Medical University, 2025) Assali, Y.; Bourtal, Y.; El Akkaoui, I.; Mustafa, H.; Tkachenko, О. V.; Ткаченко, Олена Вікторівна
    Studying the typological aspects’ impact on human organism functioning in norm and disease represents an actual branch of theoretical and applied Biology and Medicine. The authors analyzed ethnic, ethnic-gender, ethnic-age, ethnic-gender-age typological aspects as well as interhemispherical asymmetry individual profile. They were found to be concerning to social factors impact on human organism, as well as pathological conditions’ distribution and Moroccan peculiarities. The authors assessed the typological aspects contribution into social factors and morbidity patterns (in inflectional diseases, Pediatry, Neonatology and Adolescent Medicine, Oncology) in Morocco while performing the literary review of scientific sources for 2021-2024 concerning to social factors (smoking, media improper usage) impact and pathological conditions’ distinguishing features in the Moroccans.