Перегляд за Автор "Brodskaya, Anna"

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    Cutting-edge strategies in contemporary laparotomic surgery: emerging technologies, techniques, and future advancements
    (Полтавський державний медичний університет, 2025) Korniichuk, Vadym; Brodskaya, Anna; Verbitskiy, Igor; Kurmanskyi, Andrii; Honcharenko, Petro; Корнійчук, Вадим Йосипович
    Introduction: Laparotomy is one of the most common surgical interventions, but postoperative wound healing is associated with a significant risk of complications such as infection, entrapment and postoperative hernia. Current laparotomy wound management practices using standard sutures and antiseptic treatments frequently fail to achieve optimal healing results. Methods: The medical field shows increased enthusiasm for advanced wound management techniques like VAC therapy and bioengineered materials, which present fresh opportunities for enhanced patient recovery. Gene and molecular therapy is an up-and-coming field because it speeds up wound healing by stimulating the formation of new blood vessels and tissue regeneration. In this process, vectors help produce key growth factors like VEGF, PDGF, and FGF. RNA interference technology helps wound healing by reducing the activity of inflammatory cytokines TNF-α and IL-1β to control inflammation. New surgical treatments include laser therapy, photodynamic therapy, and advanced biomaterials. Results: This paper examines different treatments for laparotomy wounds and checks their effectiveness using clinical research. It also shows how modern biotechnologies, like nanomaterials and gene therapy, can help reduce problems after surgery. Conclusions: More studies in this field can improve surgical methods, speed healing, and help patients recover better.