Перегляд за Автор "Digtiar, N."

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    A rare case of Bordetella avium pneumonia complicated by Raoultella planticola
    (John Wiley & Sons Ltd, 2020) Lavrenko, A.; Digtiar, N.; Gerasymenko, N.; Kaidashev, I.; Лавренко, Анна Володимирівна; Дігтяр, Наталія Іванівна; Герасименко, Наталія Дмитрівна; Кайдашев, Ігор Петрович
    Bordetella avium pneumonia immunocompromised the patient with subsequent complication by a rare opportunistic Raoultella planticola infection, which became a nosocomial pathogen in the healthcare setting. Пневмонія Bordetella avium знизила імунітет пацієнта з подальшим ускладненням рідкісною умовно-патогенною інфекцією Raoultella planticola, яка стала нозокоміальним патогеном у медичних закладах.
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    Etiology and efficacy of anti-microbial treatment for community-acquired pneumonia in adults requiring hospital admission in Ukraine
    (2022) Kaidashev, I.; Lavrenko, A.; Baranovskaya, T.; Blazbko, V.; Digtiar, N.; Dziublyk, O.; Gerasymenko, N.; Iasdyna, L.; Kryvetskyi, V.; Kuryk, L.; Rodionova, V.; Stets, R.; Vysbnyvetskyy, I.; Fesbcbenko, Yu.; Кайдашев, Ігор Петрович; Лавренко, Анна Володимирівна; Дігтяр, Наталія Іванівна; Герасименко, Наталія Дмитрівна
    Background and aim: Empiric therapy of community-acquired pneumonia (CAP) remains the standard care and guidelines are mostly based on published data from the United States or Europe. In this study, we determined the bacterial etiology of CAP and evaluated the clinical outcomes under antimicrobial treatment of CAP in Ukraine. Methods: A total of 98 adult subjects with CAP and PORT risk II-IV were recruited for the study. The sputum diagnostic samples were obtained from all patients for causative pathogen identification. Subjects were randomly assigned in a 1:1 ratio to receive delafloxacin 300 mg (n=51) or moxifloxacin 400 mg (n=47) with blinding placebo. The switch to oral treatment was after a minimum of 6 IV doses according to clinical criteria. The total duration of antibacterial treatment was 5-10 days. In vitro susceptibility of pathogens to delafloxacin and other comparator antibiotics was determined. Results: The most frequently isolated pathogens in adults with CAP were S. pneumoniae - 19.5%, M. pneumoniae - 15.3%, H. influenzae - 13.2%, S. aureus - 10.5%, K. pneumoniae - 10.1%, and H. parainfluenzae - 6.4%. All isolates of S. pneumoniae, S. aureus, M. pneumoniae had sufficient susceptibility to appropriate antibiotics. 9.0% of H. influenzae strains were susceptible to azithromycin. 94.8 % of patients had a successful clinical response to delafloxacin at the end of treatment and 93.9 % - at test-of-cure. Conclusions: In Ukraine, the major bacterial agents that induced CAP in adults were S. pneumoniae, M. pneumoniae, H. influenzae, S. aureus, K. pneumoniae, H. parainfluenzae, E. cloacae, L. pneumophila. Delafloxacin is a promising effective antibiotic for monotherapy for CAP in adults and could be used in cases of antimicrobial-resistant strains.
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    Innovative issues of improving the quality of the educational process
    (Полтавський державний медичний університет, 2023) Digtiar, N.; Gerasimenko, N.; Lavrenko, А.; Avramenko, Ya.; Дігтяр, Наталія Іванівна; Герасименко, Наталія Дмитрівна; Лавренко, Анна Володимирівна; Авраменко, Яніна Миколаївна
    In today's conditions of an ever-increasing flow of information, which previously a person received throughout his life, modernization of the educational space is needed, based on innovative strategies using the latest achievements of science and practice. It is not so much necessary to transfer to students the amount of this or that knowledge, but to teach them to acquire this knowledge independently, to be able to navigate in the information space, to use the acquired knowledge, which in general contributes to the development of critical thinking and the formation of professional competences, which will be used in the future in the conditions of continuous self-education