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Документ Optimized treatment of elderly patients with type 2 diabetes mellitus and hypertension in general practice(Заславський О.Ю., 2024-04) Kazakov, Yu. M.; Muravlova, O. V.; Nastroga, T. V.; Kitura, O. E.; Shut, S. V.; Казаков, Юрій Михайлович; Муравльова, Оксана Василівна ; Настрога, Тетяна Вікторівна; Кітура, Оксана Євгенівна; Шуть, Світлана ВолодимирівнаHypertension and type 2 DM are among the leading cardiovascular risk factors. The purpose of the study was to increase the effectiveness of treatment and improve the quality of life of elderly patients with combined pathology of hypertension and type 2 DM by additional inclusion of empagliflozin and L-arginine in the basic therapy. Materials and methods. Fifty elderly patients with comorbid pathology were under our observation for second stage hypertension, coronary heart disease (functional class II) and type 2 DM in the stage of subcompensation. Participants were divided into two groups: the first one, controls (n = 25), received generally accepted basic therapy. In the second group (n = 25), the following drugs were added to the basic therapy: empagliflozin 10 mg/day, L-arginine 300 mg/day. Results. Clinical observation in outpatient conditions lasted for 3 months. Comprehensive therapy in the elderly patients with comorbid pathology of hypertension and type 2 diabetes, with the additional inclusion of empagliflozin and L-arginine to the basic therapy, contributes to a significant positive effect on the clinical course, reduces the risk of progression of this constellation. Conclusions. The application of the proposed comprehensive therapy in outpatient conditions under the control of a family doctor will significantly improve the quality of life of patients and prevent the development of complications.