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  • Ескіз
    Документ
    Comparative effectiveness of intermittent fasting strategies for cardio-metabolic risk reduction
    (Сумський державний університет, 2025-05-18) Mansi; Prykhodko, N. P.; Shaposhnyk, O. A.; Приходько, Наталія Петрівна; Шапошник, Ольга Анатоліївна
    Intermittent fasting (IF) has recently gained significant attention as a non-pharmacological approach to metabolic disorder management. However, the selection of optimal IF protocols remains controversial, with limited comparative effectiveness data available. This study analyzes 11 randomized controlled trials investigating four intermittent fasting (IF) protocols: 5:2 diet (n=3 studies), alternate-day fasting (ADF; n=4), modified ADF (MADF; n=2), and time-restricted eating (TRE; n=2). Primary outcomes included weight loss, metabolic markers, and adherence rates, with data presented as mean ± standard deviation or 95% confidence intervals.
  • Ескіз
    Документ
    Effects of intermittent fasting on cardiovascular biomarkers, lipid metabolism, and general cardiovascular health
    (Вінницький національний медичний університет ім. М. І. Пирогова, 2025-04-18) Mansi; Prykhodko, N.P.; Shaposhnyk, O.A.; Приходько, Наталія Петрівна; Шапошник, Ольга Анатоліївна
    Relevance: dyslipidemia and metabolic disorders are key contributors to cardiovascular diseases (CVDs), which continue to be the world's leading cause of morbidity and mortality. Due to the inconsistent results of traditional dietary therapies, there is growing interest in intermittent fasting (IF) as a substitute. Improved lipid metabolism, increased insulin sensitivity, and decreased inflammation—all important components of cardiovascular health—have been associated with intermittent fasting (IF), which alternates between periods of fasting and eating. Even with encouraging first findings, long-term cardiovascular effects are still unknown and need more investigation.