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Документ Immunohistochemical changes in the adrenal glands of white rats in the late stages of the experiment(2025-01-30) Donchenko, S. V.; Bilash, S. M.; Koptev, M. M.; Pirog-Zakaznikova, A. V.; Jha, S. K.; Mishra, S.; Донченко, Світлана Владиславівна; Білаш, Сергій Михайлович; Коптев, Михайло Миколайович; Пирог-Заказникова, Ангеліна ВалеріївнаTaste plays a key role in human life, influencing the quality of food products and the pleasure of eating. In modern conditions, the food industry widely uses additives and presser vatives that can negatively affect health, particularly increasing the risk of developing cancer. This study focuses on the effect of a complex of food additives, such as monosodium glutamate, sodium nitrite, and Ponceau 4R, on the functioning of the adrenal glands in rats.Документ Morphological and functional state of the adrenal glands of rats in normal conditions and changes in the diameters of the cortical substance and medulla after exposure of a food additive complex(Полтавський державний медичний університет, 2023) Donchenko, S. V.; Mishra, S.; Донченко, Світлана ВладиславівнаIt was established that the use of food additives (monosodium glutamate, sodium nitrite and Ponceau 4R) directly affects the cortex and medulla of the adrenal glands, causing hypertrophy and perivascular edema in the early stages ofthe experimental study, the reversibility ofthe processes within 8-10 weeks oftaking food additives and irreversibility with alteration of cells and destructive changes of endocrinocytes starting from the 16th week of experimental studies.Документ The influence of a complex of food supplements on the morphometric and morphofunctional changes of the average total diameter of the capillaries of the medulla of the adrenal glands at the early stages of the experimental research(Полтавський державний медичний університет, 2024-03-28) Mishra, S.; Zakaznykova, I.; Batrachenko, S.Aim. Determine the average total diameter of the capillaries of the medulla at the early stages of the experiment.