Перегляд за Автор "Mustafa, Hanan"

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  • Ескіз
    Документ
    Diabetes mellitus peculiarities
    (Тернопільський національний медичний університет, 2025) Mustafa, Hanan; Fouzan, Mohammed; Raj, Rai Kabi; Tkachenko, O. V.; Ткаченко, Олена Вікторівна
    Diabetes mellitus belongs to one of the most prevalent diseases worldwide and its incidence is still getting increased. Pakistan doesn’t represent an exception. This disease is considered to be dominating in this country or, with other words, is a major public health concern. 642 mln of the sick are expected to be in a whole world by 2040, approximately 7,6% (5,2 mln) of Pakistanian people suffer from this disease. International Diabetes Federation forecasting mentioned 15% (14 mln) of the Pakistanians as possible patients by 2030. Nowadays Pakistan takes the 7 th position on morbidity and it is expected to be the 4 th one by 2030. That is why multi-faceted investigations with intercultural exchange are of crucial importance. The authors analyzed ethnic, ethnic-age, ethnic-gender, ethnic-gender-age typological aspects as well as urbanization contribution into diabetes mellitus distinguishing features in Pakistan. The authors analyzed modern literature (for 2019-2025) on diabetes mellitus peculiarities in Pakistan. Significant distribution of diabetes mellitus, both its clinical and latent forms, problems with proper early diagnostics, poor knowledge of population about this disease, vast complications create the situation of real challenge to healthcare system in Pakistan. Prevalence of insulin- independent diabetes mellitus and typological aspects contribution into country peculiarities on this disease should also be mention as well.
  • Ескіз
    Документ
    New molecular-biological and genetic methods applied in African countries
    (Тернопільський національний медичний університет, 2025) Fouzan, Mohammed; Mustafa, Hanan; Entonu, Peter; Tkachenko, О. V.; Ткаченко, Олена Вікторівна
    Innate pathology level in Africa exceeds high-income countries on 20%. Hemoglobinopathies, G6PD deficiency, albinism, neural tube defects are prevalent in sub-Saharan Africa. Nigerian population having sickle-cell disease is the biggest in the world, comprising 22-25% of all the inhabitants. 2:100 of Nigerian children or 2- 3% of all newborns have it. Muscular-skeletal and gastro-intestinal congenital anomalies are prevalent in the Nigerians among all congenital diseases. Inherited myopathies were found to be dominant in the North Africa. There exist dys- advantages of old investigative methods defining essentiality to create, introduce in healthcare system and to manage the new ones – informative, rather easily to be performed and possessing multiple advantages. The authors analyzed modern literature concerning new investigative methods for medical-biological and genetic researches in African countries. Materials and methods: scientific literary sources for 2019-2025 on the topic studied. Brief analysis of literary sources testifies to their rather big set and expressed opportunities. Following methods application was analyzed: Next-Generation Sequencing (NGS), Single Nucleotide Polymorphism (SNP) Genotyping, Sanger Sequencing, Fluorescence in situ Hybridization (FISH), Restriction Fragment Length Polymorphism (RFLP), Microarray Analysis, CRISPR- Cas9 gene editing, Reverse Transcription PCR (RT-PCR), Whole Exome Sequencing (WES).