Перегляд за Автор "Pronina, O.M."
Зараз показуємо 1 - 1 з 1
Результатів на сторінці
Налаштування сортування
Документ Morphofunctional characteristics of the crypts structural components of the cecum perivulnar area by using desmosin surgical thread(Полтавський державний медичний університет, 2022) Pronina, O.M.; Kobeniak, M.M.; Проніна, Олена Миколаївна; Кобеняк, Микола МиколайовичThe paper describes the morphological changes in the structural components of the caecal crypts in the periulnar region while suturing the wound defect with desmosin surgical thread. It was determined that rabbits’ cecum, like humans, consists of four membranes: mucous, submucosa, muscular and serous. The mucous membrane included cylindrical epitheliocytes arranged in one layer on its own plate. Under the lamina propria, the mucous membrane’s muscular lamina was visualized, including smooth myositis, which were located in two layers: the inner circular and the outer longitudinal. A large number of crypts and the absence of villi were determined in the composition of the mucous membrane. In the mucosa and submucosa, the elements of the hemomicrocirculatory channel were visualized: arterioles, capillaries, and venules, which in turn provided blood circulation and blood exchange of the wall of the cecum as a whole. The structure of the cecal crypts of animals of the control group included various cell associations: columnar cells with a brush border, goblet cells, single endocrinocytes, columnar epitheliocytes without a brush border, and Paneth cells. Lieberkhun’s glands histotopographically passed through the entire mucous membrane surface, their openings opened into the lumen of the cecum, and their lower parts reached the lamina propria. Thus, it was established that the implementation of alteration processes in the perivulnar region of rabbits’ cecum begins on the 3rd day of the experimental study and is determined in the deep layers of the mucous membrane with the involvement of all its structural components. Connection to the regenerative and compensatory processes of the surface layers of the mucous membrane f rabbits cecum in the area of the wound defect sutured with Desmosin surgical thread occurs from the 7th day of observation, in which the structural components of Lieberkün’s glands are involved. Due to destructive changes in columnar epitheliocytes with a brush border in the crypts of the perivulnar area, digestion and absorption processes are disrupted and possibly stopped from the 3rd to the 7th day of the experimental study. The recovery of the pool of these cellular elements begins from the 14th day of the experiment, and the control indicators reach up to the 30th day. The restoration of the cellular composition of Lieberkün’s glands in the perivulnar region occurred due to the poorly differentiated cells, which tended to increase their average number from 3 to 21 days of the experiment. Recovery of the average number of these cells compared with control indicators occurred on the 30th day of observation.