Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії, Том 23, вип. 3 (83)
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Перегляд Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії, Том 23, вип. 3 (83) за Ключові слова "615.28:616.9"
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Документ Sensitivity of causative agents of infectious-inflammatory diseases in maxillofacial soft tissues to antibiotics(Полтавський державний медичний університет, 2023-11) Faustova, M. O.; Nazarchuk, O. A.; Loban’, G. A.; Chumak, Yu. V.; Avetikov, D. S.; Фаустова, Марія Олексіївна; Назарчук, Олександр Адамович; Лобань, Галина Андріївна; Чумак, Юлія Вікторівна; Аветіков, Давид СоломоновичThe aim of the work was to investigate the sensitivity of pathogens of infectious and inflammatory soft tissue diseases in the maxillofacial region to antibiotics. Methods: The 282 clinical isolates obtained from patients were the objects of the study. The sensitivity of the studied microorganisms to antibiotics was determined according to the EUCAST committee quality control standards. Results: The variability in the sensitivity of microorganisms isolated in infectious and inflammatory diseases of the maxillofacial soft tissues to antibiotics has been established. Representatives of the genus Staphylococcus exhibit high sensitivity to vancomycin, fluoroquinolones and lincosamides. At the same time, they are characterized by the lowest sensitivity to aminglicosites and penicillins. Enterococcus spp. have high sensitivity to tetracyclines and fluoroquinolones, showing the lowest results with penicillins and carbapenems. Streptococcuss spp. viridans-group exhibit low sensitivity to penicillins, carbapenems, fluoroquinolones, and lincosamides, while maintaining high sensitivity to glycopeptides. Low sensitivity of Acinetobacter spp. isolated from patients with infectious and inflammatory diseases of maxillofacial soft tissues to antibacterial drugs of different groups was established. Conclusions: The variability in the sensitivity of isolates to antibiotics most commonly used in clinical practice and recommended by the EUCAST quality committee was established, what provides prospects in their use.