Features of cellular composition of recurrent aphthous stomatitis lesions

Abstract

Reccurent aphtous stomatitis (RAS) is one of the most common disease of oral mucose. The etiology and pathogenesis of RAS remain unclear. Multiple factors are associated with development and onset of this disease, such as: a positive family history, food hypersensitivity, smoking cessation, psychological stress and immune disturbance. Immune dysregulation linked to several triggers may facilitate the development of RAS. The roles of the immune system and inflammatory processes have been confirmed in recent large-scale bioinformatics analyses.