Creating a genetic database аs a strategic challenge of modern medical researches

Abstract

Research Institute for Genetics and Immunological Grounds of Pathology and Pharmacogenetics among the first institutions in Ukraine had created a genetic database growing for the last few years. The creation of this database is necessary to monitor such common pathological conditions as metabolic syndrome, diabetes, arterial hypertension, coronary heart disease, allergic inflammation, urogenital infections, pathologies of immune and endocrine systems, and connective tissue. Creation of genetic monitoring system and identifying genetic markers of susceptibility to infectious agents and propensity to noninfectious origin diseases development will allow monitoring the level of morbidity in Ukraine by predicting the risk of developing certain pathological conditions, the nature and progression rate of pathological process, the formation of risk groups of possible morbidity since the childhood, and using effective prevention technologies. Development of targeted programs for early diagnosis and treatment taking into account a genetic predisposition will reduce the direct economic costs of medication, duration of outpatient and inpatient treatment by pharmacogenetic selection of main groups of drugs, decrease the incidence of complications and mortality level and will promote the introduction of individual strategies of preventive measures and improving health.