Immunohistochemical characterization of mucosal glands of the human frontal sinus septum mucosa in normal state
Ескіз недоступний
Дата
2023
Назва журналу
Номер ISSN
Назва тому
Видавець
WHO Office in Azerbaijan
Анотація
The immunohistochemical characteristics of the glands of the mucous membrane of the septum of the
human frontal sinus were studied in normal conditions.
The study was conducted on 120 preparations of the glands of the mucous membrane of the septum of the
frontal sinus in 52 corpses of people of both sexes aged from 30 to 87 years who died from causes not related
to the pathology of the paranasal sinuses. Our study used such methods as collecting material from corpses
and the subsequent method of preparing the material for histochemical studies, serial semi-thin sections, and
immunohistochemical analysis.
According to an immunohistochemical study, it was established that in the stroma of the septal glands,
there are CD 3-positive cells, which are elements of the local protective barrier, as well as a large number of
periacinar T-lymphocytes. The number of CD 20-positive cells is negligible in the periacinar connective
tissue of the septum. The number of B lymphocytes in the periductal stroma was significant. Many plasma
cells were identified in the periacinar stroma of both protein and mucous glands of the mucous membrane of
the human frontal sinus. The cells formed chains of 10-12 cells along the basement membrane. The number
of CD 138-positive cells in the periductal connective tissue was lower compared to the periacinar tissue.
Опис
Ключові слова
mucosal glands, human, frontal sinus, mucosa, immunohistochemical analysis
Бібліографічний опис
Immunohistochemical characterization of mucosal glands of the human frontal sinus septum mucosa in normal state / O. M. Pronina, S. M. Bilash, M. M. Koptev, A. V. Pirog-Zakaznikova, B. S. Kononov, Ya. O. Oliinichenko, S. V. Donchenko, V. V. Oleksiienko, O. V. Mamai // Azerbaijan medical journal. – 2023. – № 4. – P. 134–1140.