2022
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Перегляд 2022 за Автор "Bezshapochnyy, S. B."
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Документ Etiopathogenesis problems of the nasal mucosa at atrophic rhinitis(Полтавський державний медичний університет, 2022) Bezega, M. I.; Bezshapochnyy, S. B.; Loburets, V. V.; Loburets, A. V.; Bondarenko, R. V.; Bondarenko, V. V.; Dzhirov, O. R.; Безега, Михайло Іванович; Безшапочний, Сергій Борисович; Лобурець, Валерій Васильович; Лобурець, Андрій Валерійович; Бондаренко, Руслан Валерійович; Бондаренко, Валерій Володимирович; Джіров, Олексій РомановичThe article presents and considers common problems of etiology and pathogenesis of atrophic rhinitis in our time. Atrophy of the nasal mucosa is relevant and widespread today. Given the complicated etiopathogenetic mechanism, this pathology can lead to nasal cavity complications, such as impaired mucociliary clearance and evacuation function of the nasal mucosa and physiological, histological, and morphological changes in nasal mucosa atrophy. We analyzed an extensive studies number on the pathogenetic aspects of the development of the nasal mucosa atrophic changes that may affect its development, namely: vascular disorders of nasal tissues microcirculation, genetic predisposition, hypoxia of mucous tissues, climate change, environmental conditions, labor conditions, bad habits, exposure to drugs and the mental state of the patient that provoke the atrophic phenomena development and lead to ciliated epithelium dysfunction due to changes in the vascular bed. Another critical factor in the development of nasal mucosa atrophy is damage to the chemical composition of nasal secretions. A weak clinical picture complicates the diagnosis of these pathological conditions because it begins to disturb the patient only in the critical disease stages, which significantly complicates the patient’s treatment. If we ignore this problem, it can progress and provoke more severe complications up to nasal septum perforation, deformation of the outer nose or ozena, and cause disorders of other organs and systems or patient’s mentality