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Документ Adverse factors that can affect on the course of chronic parenchimatic parotitis in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Bilokon, S. O.; Popelo, Yu. V.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія МиколаївнаThe aim: The study of the presence of disorders in the ante- and postnatal periods of development of children from 2 months to 15 years with chronic parenchimatic parotitis, which may affect its course. Materials and methods: It has been examined and treated 88 children, aged from 2 months to 15 years with chronic parenchimatic parotitis, and their mothers were interviewed, who indicated the pathological course of pregnancy, childbirth and indicated the type of breastfeeding babbies. The scope of the survey included general, additional methods, consultations by related specialists and statistical processing of results. Results: 88 children with the exacerbation of chronic parenchimatic parotitis were examined (42 – (47%) with active course and 46 – (53%) with inactive). The exacerbation occurred on the background of acute infectious processes or coincided with the exacerbation of one of the chronic diseases. The first manifestations occurred in spring (55%) and autumn (36%) periods, 44% of children were hospitalized with other diagnoses. The presence of pathological conditions during pregnancy and birth defects in their mothers were recorded more often 3,5 and 3,3 times, respectively, compared with control. 70% of children received mixed and artificial feeding and were more likely to become ill. Conclusions: The severity of clinical manifestations of inflammation and disorders of the general condition depended on the activity of the course of chronic parenchymatic parotitis and were more pronounced when active. During the remission period, no apparent clinical manifestations were detected in 72% of observations, however, in 28%, the identified signs indicated a latent course, which required additional treatment and rehabilitation measures.Документ Bitten wounds of the maxillofacial area in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Bilokon, S. O.; Dolenko, O. B.; Korotych, N. M.; Popelo, Yu. V.; Bilokon, N. P.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Попело, Юлія Вікторівна; Білоконь, Наталія ПавлівнаThe aim of the work is to determine the frequency, structure, features of clinical manifestations and treatment of bitten wounds of the face and neck in children of Poltava region. Materials and methods: It has been analyzed 91 histories of disease of thematic patients undergone treatment at the Surgical Department of Pediatric town clinical hospital of Poltava. Results: In the structure of traumatic injuries of maxillofacial area in children 5.3% were patients with bitten wounds of the face and neck. Among the injured were children of the age 7-12 years old (30.2%). In 74.7% of cases, the bites were complicated by acute inflammatory processes. Urban residents accounted for 71.8% of the total number of cases, while rural residents accounted for 28.2%. Boys were injured by 53.6% and girls by 46.4%. Sharps (74.5%), punctures (19.3%) and lacerations (6.2%) differed in form. The comprehensive treatment of patients with bitten maxillofacial area wounds was carried out according to the protocol of care. Conclusions: The clinical picture and severity of bitten wounds of maxillofacial area in children have individual features, which are largely due to topographic and anatomical localization of injuries. The choice of the optimal variant of primary surgical treatment of wounds and the amount of surgery should be determined individually depending on the severity of the injury, the time of injury. Special attention should be paid to normalization of psycho-emotional state of patients and prevention of scar formation.Документ Clinical and morphological features of follicular cysts of jaw in children(2023) Tkachenko, P. I.; Bilokon, S. O.; Dolenko, O. B.; Lokhmatova, N. M.; Popelo, Yu. V.; Korotych, N. M.; Bilokon, Yu. S.; Lachabi, Reda; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Попело, Юлія Вікторівна; Коротич, Наталія Миколаївна; Білоконь, Юлія СергіївнаДокумент Clinical characteristic of different types of conservative treatment os pathological scars of head and neck(Полтавський державний медичний університет, 2023) Tkachenko, P. I.; Lokes, K. P.; Bondarenko, V. V.; Bilokon, S. O.; Ivanytska, O. S.; Rezvina, K. Y.; Ivanicky, I. O.; Ткаченко, Павло Іванович; Локес, Катерина Петрівна; Бондаренко, Валерій Володимирович; Білоконь, Сергій Олександрович; Іваницька, Олена Сергіївна; Резвіна, Катерина Юріївна; Іваницький, Ігор ОлексійовичThere are a lot of different types of conservative and surgical treatment of pathological scars. The purpose of study was to analyze the result of using of ultraphonophoresis of Contractubex and electrophoresis with lidase in case of conservative treatment of scars of maxillofacial region. The study involved 40 patients of the Department of Maxillofacial Surgery of the Poltava Regional Clinical Hospital with pathological scars of maxillofacial localization. All patients were divided into two clinical groups of 20 people each. Patients of the first clinical group were administered the Contractubex daily using ultraphonophoresis. Patients of the second clinical group underwent electrophoresis with lidase. The nature of the scars was assessed by four clinical signs (type, texture, color and sensitivity), expressed on a 4-point scale. Both methods of conservative treatment of maxillofacial scars have a predominant effect on subjective indicators, such as itching. A more pronounced effect of treatment was noted after the use of ultraphonophoresis of contractubex, in this group of patients there was also a significant improvement in such an objective clinical indicator as the color of the scar. The use of lidase electrophoresis led only to a reliable improvement in subjective feelings (P4), in the absence of such in relation to three objective indicators. Thus, the investigated methods of conservative treatment mainly affect the subjective characteristics of scar tissue. Moreover, the use of contractubex ultraphonophoresis has a more pronounced effect than the use of lidase electrophoresis.Документ Clinical-morphological characteristics and peculiarities of treatment of paraururicular fistulas in children(Wydawnictwo Aluna, 2020) Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Popelo, Yu. V.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Hohol, A. M.; Bilokon, N. P.; Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Гоголь, Андрій Михайлович; Білоконь, Наталія ПавлівнаThe aim: Determining the frequency of occurrence of paraauricular fistula in children and comparing the results of their own experience regarding their clinical manifestations, treatment principles and morphological features with existing scientific data. Materials and methods: The results of a comprehensive examination and surgical treatment of 25 children with paraauricular fistulas. Results: Most often, para-auricular fistula was observed in infants 22 – (88%). In 18 persons (72%), they were unilateral, in 10 – (40%) hereditary. In 8 – (32%), fistula was diagnosed immediately after birth. In 17 – (68%) the pathology was not clinically manifested, but was an accidental finding during the next medical examination. Morphological research has shown that congenital paraauricular fistula is a formed canal intimately associated with the epithelium and cartilage, and the presence of epithelial lining on the fistula wall with constant support of the inflammatory process makes it impossible to heal even against the background of multicomponent treatment. Conclusions: Due to the topographic-anatomical localization, features of the clinic of the born fistula, surgical treatment does not always allow to achieve the desired results, and requires repeated interventions during recurrence. It is possible to prevent recurrence by the extensive use of additional diagnostic manipulДокумент Clinicomorphological characteristics of the wound process at the early postoperative period after radical uranostaphyloplasty(Українська медична стоматологічна академія, 2019) Tkachenko, P. I.; Dolenko, О. B.; Lokhmatova, N. M.; Bilokon, S. O.; Dobroskok, V. O.; Ткаченко, Павло Іванович; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Білоконь, Сергій Олександрович; Доброскок, Віталіна Олексіївна; Ткаченко, Павел Иванович; Доленко, Ольга Борисовна; Лохматова, Наталия Михайловна; Белоконь, Сергей Александрович; Доброскок, Виталина АлексеевнаThe purpose of the paper was to study the clinical situation and the morphological structure of the biopsy material of the hard palate mucoperiosteal grafts in children with the congenital cleft palate before surgery and at the early postoperative period after radical uranostaphyloplasty. The study of clinical characteristics and general somatic state of children with this pathology before operative intervention enables to reveal the marked anatomical and functional disorders. The study of the wound process at the early postoperative period after radical uranostaphyloplasty with the help of morphological structure of the biopsy material of the hard palate mucoperiosteal grafts enables to predict the degree of probability of the formation of dense scar and make individual plan of treatment-and-prophylactic and rehabilitation measures for this category of patients. Метою роботи було вивчення клінічної ситуації та морфологічної структури біоптатів слизово-окісних клаптів піднебіння у дітей з його вродженими незрощеннями до оперативного втручання та в ранньому післяопераційному періоді після радикальної ураностафілопластики. Дослідження клінічної характеристики та загально соматичного стану у дітей з цією патологією до оперативного втручання дозволило виявити у них виражені анатомічні та функціональні порушення. Вивчення ранового процесу в ранньому післяопераційному періоді після радикальної ураностафілопластики за допомогою морфологічної структури біоптатів слизово-окісних клаптів піднебіння дає змогу спрогнозувати ступінь вірогідності формування щільного рубця, та скласти індивідуальний план лікувально-профілактичних і реабілітаційних заходів для цієї категорії хворих.Целью работы было изучение клинической ситуации и морфологической структуры биоптатов слизистонадкостничных лоскутов неба у детей с его врожденными несращениями до оперативного вмешательства и в раннем послеоперационном периоде после радикальной ураностафилопластики. Исследование клинической характеристики и общего соматического состояния у детей с этой патологией до оперативного вмешательства позволило выявить у них выраженые анатомические и функциональные нарушения. Изучение раневого процесса в раннем послеоперационном периоде после радикальной ураностафилопластики с помощью морфологической структуры биоптатов слизисто-надкостничных лоскутов неба позволяет спрогнозировать степень достоверности формирования плотного рубца, и составить индивидуальный план лечебно-профилактических и реабилитационных мероприятий для этой категории больных.Документ Differential-diagnostic informativeness of the morphological and immunohistochemical study of parotid salivary gland cysts(Aluna Publishing, 2023-09) Tkachenko, P. I.; Rezvina, K. Yu.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, O. B.; Popelo, Yu. V.; Shvets, A. I.; Ткаченко, Павло Іванович; Резвіна, Катерина Юріївна; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Попело, Юлія Вікторівна; Швець, Анатолій ІвановичThe aim: To conduct a general analysis of the results of the study of the morphological and immunohistochemical structure of cysts of the parotid salivary glands. Materials and methods: Our study is based on the application of generally accepted, additional and special methods of examination, which concerns 21 patients who underwent surgical intervention to remove cystic formations of the parotid salivary gland. Results: It was established that there are 2-3 HLA-DR+ cells per 100 epithelial cells located in the basal and subbasal layers in the form of their continuous ribbon and their moderate infiltration of tissues within the acinar epithelium. In the epithelium, CD3+ cells were also detected in the number of 1 to 7 per 100 epitheliocytes and they were the most numerous, along with HLA-DR+ cells. Instead, the presence of CD4+ and CD20+ cells was not detected in the epithelium, unlike the subepithelial layer, where they occupied significant areas. In turn, the infiltration of CD8+ cells of the epithelial layer was established in the amount from 1 to 7 per 100 epitheliocytes. A moderate number of them was also determined subepithelially, and they were single directly in the cyst wall. Conclusions: Immunohistochemical study of the structural components of cystic formations is this is the direct way to establish the nature of the redistribution of immune cells in it, which is very important when conducting differential diagnosis in difficult and doubtful cases.Документ Difficulties of the diagnosis and treatment of dermoid and epidermoid cysts of the maxillofacial area and the neck among children(Національний медичний університет імені О. О. Богомольця, 2020) Tkachenko, P. I.; Bilokon, S. O.; Bilokon, Y. S.; Shevchuk, A. R.; Fleischhauer, S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Білоконь, Юлія СергіївнаIt is generally accepted that dermoid and epidermoid cysts are the result of malformation of the ectoderm. The asymptomatic course, absence of pathognomonic symptoms and similarity of clinical manifestations at separate stages of growth, despite nosological form and place of occurrence, give this pathology of particular relevance in the practice of pediatric maxillofacial surgery. However, if there are no significant issues regarding the etiology and pathogenesis of dermoids and epidermoids, there is a problem of constant monitoring of their prevalence and structure for the formation of administrative organizational measures for the planning of specialized care for this category of patients. Special attention should also be given to the development of new, minimally invasive surgical interventions, given the increasing aesthetic demands and requirements of patients. The aim of the study is to study in a comparative aspect their own experience on the clinical and morphological features and principles of treatment of dermoid and epidermoid cysts of the maxillofacial area and neck in children with the results of scientific studies, covered in literature. A thorough analysis of fundamental scientific works and publications in periodicals devoted to the scientific development of various directions in relation to these issues is carried out. The clinical section of the work concerns 15 children with dermoids and 8 children with epidermoids who have been treated for 8 years in the surgical ward of the children’s clinical hospital in Poltava. General clinical, additional, and specific examination methods were used to establish clinical diagnosis, including diagnostic puncture, ultrasound, and MRI examination, which was performed in complex and questionable cases. If necessary, the patients were consulted by doctors of related specialties. The microscopic structure of the postoperative material was studied on preparations made by conventional methods. An objective study found that the clinical picture of the dermoid and epidermoid cysts is similar, differing only in slight subjective sensations on palpation. Comparison of clinical diagnosis and results of postoperative morphological verification of removed soft tissue bones showed that in 23.9% of patients the clinical diagnosis did not coincide with pathohistological. The difference in dermoids was the largest (75.0%), which confirms the need for expanded use of additional examination methods both at the prehospital stage and under inpatient conditions immediately before surgery. In general, the obtained morphological picture of the postoperative material coincided with the literature data on the classical structure of the dermoid and epidermoid cysts of the soft tissues of the maxillofacial area. Thus, the dermoid and epidermoid cysts of the maxillofacial area in children, having a dysontogenic origin, are most often diagnosed at younger and older school age. Despite their classic clinical picture, a considerable number of discrepancies between clinical and pathohistological diagnoses are traced, requiring a careful examination at both the hospital and hospital stages using modern, informative supplementary and special methods of investigation in complex and doubtful cases of cases and complex cases. These materials may be the basis for further in-depth scientific studies on immunohistochemical structural features dermoids and epidermoids to determine immunocompetence layers cystic membranes and determine their probable role in causing acute inflammation depending on the type of formation.Документ Difficulties of the diagnosis and treatment of traumatic and aneurysmal cysts of the jaws(Національний медичний університет імені О. О. Богомольця, 2020) Tkachenko, P. I.; Bilokon, S. O.; Shevchuk, A. R.; Bilokon, Y. S.; Fleischhauer, S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Білоконь, Юлія СергіївнаThe great diversity of the jaw cysts makes the issues of their diagnosis, differential diagnosis and treatment quite important, always requiring individual approach, given the features of each clinical case. Although the jaw cysts were first mentioned by Scultetus in 1654, the researchers still have different views on the semiotics and group belonging of individual nosological forms in the classifications and, consequently, on120 the choice of treatment method, prevention of possible complications and recurrences, and making prognosis. Asymptomatic clinical course and absence of characteristic clear clinical manifestations of the jaw cysts, similarity of their signs at separate stages of the development, regardless the nosological form and site of origin, make this pathology relevant in the practice of maxillofacial surgery. Traumatic and aneurysmal pseudocysts are common in the nomenclature of tumor-like formations of the jaws. The paper is concerned the etiology and pathogenesis, clinical morphological features and modes of treatment of traumatic and aneurysmal jaw cysts, based on the generalization of the findings of the scientific researches, to emphasize the above nosological forms to the medical community. The study encompassed the thorough analysis of the fundamental scientific works and publications in periodicals on above issues. The clinical part of the study concerned a comprehensive examination of 46 children with traumatic and aneurysmal jaw cysts who received treatment at the surgical unit of the Poltava Municipal Children’s Clinical Hospital during the period of 5 years. In addition, 8 adult patients with traumatic cysts were examined and received outpatient treatment at the Department’s clinic. Common clinical and additional examination methods, diagnostic puncture, EOD, radiography, CT and MRI were used to make the clinical diagnosis in serious cases. The microscopic structure of the specimens made from the postoperative material using conventional techniques, was studied. During 2014-2019, 46 children with neodontogenic jaw cysts (NJC) were treated at the Department of Children’s Oral Surgery, including 24 patients (52.2%) with traumatic cysts (TC) and 15 patients (32.6%) with aneurysmal cysts (AC). That is, TC and AC were accounted for 39 cases (84.8%) of NJC. At the same time, if the general age of patients with NJC ranged from 5 to 15 years, then TC and AC were most common in children aged 10-15 years, which is in concordance with the data of other researchers, who mark their highest percentage in puberty. 25 (64,1%) boys and 14 girls (35.9%) have been involved into study. Generalized statistical analysis revealed that traumatic cysts accounted for 52.2% of children, 32.6% for aneurysmal, 15.2% for other types of non-odontogenic jaw cysts. Among patients, boys predominated, and even121 trauma in the past medical history does not always correspond and confirm the type of cystic formation. The presented material suggests a rather conditional diagnostic «boundary» between traumatic and aneurysmal cysts, when, in fact, the main differential diagnostic criterion is a carefully gathered anamnesis, even at the prehospital stage. The given material can be the basis for further in-depth scientific and practical studies on the study of immunohistochemical structural features of traumatic and aneurysmal jaw cysts.Документ Effectiveness of preventive measures in the inactive course of chronic parenchymatic mumps in children(Wydawnictwo Aluna, 2022) Тkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, O. B.; Popelo, Yu. V.; Korotych, N. M.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Попело, Юлія Вікторівна; Коротич, Наталія МиколаївнаSUMMARY Aim: To study the effectiveness of preventive measures in the inactive course of chronic parenchymal mumps in remission. Materials and Methods: In the dynamics of precautionary measures, aimed at preventing of exacerbation of chronic processes in the parotid glands, were examined 29 children aged from 2 months to 16 years with inactive mumps in remission and 10 control persons aged from 7 to 15 years. Results: According to the assessment of the cellular composition of parotid secretion before anti-relapse measures in 9 patients out of 19, it was possible to detect the presence of latent chronic inflammation in symmetrical glands in the absence of classical clinical symptoms and clear secretion. After the completion of the treatment-and-prophylactic complex, the number of inflammatory cells and the degree of its contamination with microorganisms decreased significantly. Conclusions: The study of the composition of parotid secretion with taking into account of the results of ultrasound examination and sialography in the dynamic monitoring of chronic parenchymal mumps indicate its high diagnostic informativeness and allows a rational approach to planning preventive measures. The methodological approach, which was developed and tested by us and which was used in the active course of mumps, showed its high efficiency and inactive form of the disease, for the first year of observation the number of exacerbations decreased by 10 times, and for 5 years term- by 16 times, which allowed to prolong the remission period and improve the rheological properties of parotid secretion.Документ Effectiveness оf correction of psycho-emotional stress in children with traumatic injury to soft tissues and facial bones(Aluna Publishing, 2021) Tkachenko, P. I.; Lokhmatova, N. M.; Bilokon, S. O.; Popelo, Yu. V.; Dolenko, O. B.; Korotych, N. M.; Pankevych, A. I.; Kolisnyk, I. A.; Ткаченко, Павло Іванович; Лохматова, Наталія Михайлівна; Білоконь, Сергій Олександрович; Попело, Юлія Вікторівна; Доленко, Ольга Вячеславівна; Коротич, Наталія Миколаївна; Панькевич, Артур Іванович; Колісник, Інна АнатоліївнаThe aim: To study the effectiveness of correction of psycho-emotional stress in children with traumatic injuries of the tissues of the maxillofacial area. Materials and methods: A comprehensive examination and treatment of 58 children aged 3 to 15 years with traumatic injuries of the maxillofacial area were conducted during the period of 5 years. This applied to soft tissue injuries in 51.7% of cases and in 48.3% - to facial bone injuries. To test the severity of the psycho-emotional state, two homogeneous groups were formed in a total of 41 persons of primary and secondary school age. Results: A comparison of the results of our previous studies, which concerned only the fact of psychological testing and changes in vegetative balance in children with traumatic injuries with a group of patients who underwent comprehensive treatment with additional involvement of targeted psychoneuropharmacological correction allowed to establish, that this approach made it possible to eliminate vegetative disorders and reduce the degree of stress in them for 9-10 days from the time of hospitalization. Conclusions: In children with traumatic injuries of soft tissues and bones of the face, dysregulation of vegetative function and intensity of compensatory-adaptive mechanisms of the body with the predominance of the central mechanism of regulation. With the additional involvement of the drug “Noofen®” in the complex of therapeutic measures, it allows to stabilize their psychological state, which indicates its effectiveness.Документ Features of the course, clinical and morphological characteristics of ameloblastoma and fibrous dysplasia in children(Полтавський державний медичний університет, 2021) Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Резвіна, Катерина Юріївна; Попело, Юлія Вікторівна; Доленко, Ольга Борисівна; Лохматова, Наталія Михайлівна; Коротич, Наталія Миколаївна; Білоконь, Наталія Павлівна; Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Rezvina, K. Yu.; Popelo, Yu. V.; Dolenko, O. B.; Lokhmatova, N. M.; Korotych, N. N.; Bilokon, N. P.У статті висвітлені особливості клінічного перебігу та морфологічних характеристик, діагностичних заходів і лікування дітей з амелобластомою та фіброзною дисплазією щелепних кісток. Відсутність чітких клінічних проявів, подібність симптоматики і характер перебігу амелобластоми та фіброзної дисплазії, що є притаманним для усіх доброякісних пухлин щелепно-лицевої ділянки у дітей, обумовлюють значний відсоток діагностичних помилок, роблячи питання їх диференційної діагностики доволі актуальним для хірургічної стоматології і щелепно-лицевої хірургії.Документ Frequency, structure and clinical manifestations of thermal burns of the jaw-facial area in children(Wydawnictwo Aluna, 2021) Tkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Popelo, Yu. V.; Rezvina, K. Yu.; Hohol, A. M.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Попело, Юлія Вікторівна; Резвіна, Катерина Юріївна; Гоголь, Андрій МихайловичThe aim: To establish the frequency, structure and features of the clinical course of facial and neck burns in children. Materials and methods: During 5 years, 78 patients aged from 6 months to 15 years with isolated burns of the face and neck and in combination with lesions of other anatomical areas were treated. In the dynamics of observation of patients were used classical methods of examination, and in their treatment we followed the protocol of medical care for this category of patients. Results: Thermal injuries of the face and neck accounted for 12.6% of the total number of patients with burns. Their isolated lesion was 26.9%, and in combination with other areas it was 73.1%. The most frequently affected were children of nursery, primary school and preschool age, with a predominance of rural residents (52.6%), mostly boys (78.0%). Anesthesia support had to be used in the treatment of 24 patients (30,8%). The features and nature of the burns depended on the relief of the face and the most damaged are its protruding parts. Conclusions: Open flames were the most common cause of thermal burns of the face and neck in children, and the lesions were combined with burns to the chest, abdomen, and limbs. The main reasons were reckless behavior of children, their increased mobility and lack of care for their relatives. It should be noted that in 3.8% of victims there was a delay in mental and physical development.Документ Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors(Wydawnictwo Aluna, 2019) Popelo, Yu. V.; Tkachenko, P. I.; Bilokon, S. O.; Попело, Юлія Вікторівна; Ткаченко, Павло Іванович; Білоконь, Сергій ОлександровичIntroduction: According to modern standards of treatment of malignant neoplasms conducting polychemotherapy requires up to 90% of cancer patients. However, in addition to the expected cytotoxic effects, it is accompanied by disorders in dental health in the vast majority of patients. The aim: To study the effect of cytostatics on soft tissues of the oral cavity in children with malignant tumors of the abdominal cavity. Materials and methods: Material for writing this scientific work served as a synthesis of results for 25 people aged 7 to 15 years with malignant tumors of the abdominal cavity, in which a comprehensive oral examination was performed to determine the manifestations of dental toxicity cytostatics. Results: At the end of the first course of chemotherapy, all patients had dry redness of the lips, 20 - (80,0%) with eruptions, in 18 - (20,0%) erosion. The Green-Vermillion, PMA, and PBI indices grew by 1,8; 7 and 3,3 times respectively. In cytograms with buccal epithelium an increase in the number of cells of polymorphic sizes and forms with signs of gidropic dystrophy was found. The nuclear-cytoplasmic ratio decreased by 1,4 times compared with the primary examination. Conclusions: This situation creates the preconditions for the development of inflammatory process in the tissues of the oral cavity and requires the use in this category of patients of a substantiated pathogenetic correction of existing disorders.Документ Incidence and structure of the bening soft tissuetumors of maxillofacial region in children(Національний медичний університет імені О. О. Богомольця, 2019) Tkachenko, P. I.; Bilokon, S. O.; Bilokon, Yu. S.; Dogan, S.; Bieliaiev, I. S.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Бєляєв, Ігор СергійовичAccording to the statistical data, children with tumors of the maxillofacial region (MFR) account for 12-22% of all patients with tumors, and 90% fall to the share of benign processes, where mesenchyme-related tumors or, less frequently, epithelial neoplasms, prevail. At the same time, soft tissues tumors of face and neck account for 55-62% among the MFR cancers in children. Tumors in children have specific characteristics, in contrast to adults, and the age changes in metabolism and physiological functions of child body specify possible clinical differences in tumor processes among children of different age groups. Morphologists also highlight a number of features of child tumor processes, regardless of their localization, reminding of the possibility of transformation of some malignant tumors into benign ones. The paper is aimed at representation of our data on the incidence and structure of some nosological forms of benign tumors of head and neck in children. It has been found that in the 10-year period of our observations, the number of children with benign tumors of maxillofacial region accounted for 7,5% of the total number of patients treated in the Surgical Unit of the Poltava Children’s Municipal Clinical Hospital. Among the nosological forms, dermoid cysts (32,7%) and hemangiomas (26,0%) occurred most commonly and the peak of morbidity (25,0%) was observed in infants. In most cases (55,4%) soft tissue benign tumors and tumor masses of maxillofacial region occurred in girls, with more frequent (62,9%) occurrence of hemangiomas, whereas dermoid cysts were more frequently found in boys (61,7%). In 22,4% of the cases, the pathological focus was detected on the neck, in 14,0% on the forehead, in 10,8% in the soft oral tissue, in 7,7% on the lower lip, in 7,7% on the cheek, in 6,2% on the upper lip, and in 3,1% of patients on the chin. In 25,9% of cases, hemangiomas covered several anatomical areas at ones. Recurrences of tumors after surgery have been recorded in 6,7% of patients: in 43,0 % of children it was happened after surgical excision of the middle neck cyst and per 28,5 % of the cases of angiomas and ranulas. The comparative analysis of the clinical diagnosis and postoperative morphological study of the removed tumors has established that in 15,3% of cases the clinical diagnosis was different from the pathohistological one. In most cases it was associated with dermoids (75,0%), fibromas (15,6%) and lymphangiomas (9,4%). Considering the fact that the prognosis for children with abovementioned pathology is determined by the option of histological structure and primary localization of the tumor, the timeliness and adequacy of the treatment activities, implementation of the advanced methods of diagnostics with the high level of awareness is crucial in the improvement of the effectiveness of health care provided for patients of this category, contributing to the correct diagnosis, selection of the treatment procedure and determine the extent of surgical intervention at the preparing period.Документ Insect bites as the cause of infectious and allergic inflammatory processes of the maxillofacial area in children(Wydawnictwo Aluna, Polska, 2019) Tkachenko, P. I.; Starchenko, I. I.; Bilokon, S. O.; Prylutskyi, O. K.; Lokhmatova, N. M.; Dolenko, O. B.; Korotych, N. M.; Vakhnenko, A. V.; Gogol, A. M.; Rezvina, K. Yu.; Ткаченко, Павло Іванович; Старченко, Іван Іванович; Білоконь, Сергій Олександрович; Прилуцький, Олексій Костянтинович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Вахненко, Андрій Вікторович; Гоголь, Андрій Михайлович; Резвіна, Катерина Юріївна; Коротич, Наталія МиколаївнаTo attract attention of the medical community to the problem of the complexity of the diagnosis and treatment of these dermatogenic forms of IP MFA. The work is based on the results of 5 year observations of 42 patients with acute IP MFA arising after insect bites, their comprehensive examination and treatment. 1. IP of MFA, arising as a result of insect bites, is a very urgent problem of pediatric surgical dentistry and require an individual approach in the diagnosis and treatment of patients. 2. A large role in preventing the occurrence of these nosological forms is given to medical workers, a sufficient organization level of sanitary and educational work, and the treatment of such cases becomes a common task of doctors of different profiles. However, much depends on the parents, their level of responsibility and competency, ensuring of timely treatment and provision of qualified medical care to children, preventing the development of severe complications. 3. The issues related to the etiopathogenesis of this pathology require profound scientific research.Документ Prevalence of inflammatory diseases of the nose among patients with odontogenic purilent-inflammatory diseases of maxillo-facial location(Полтавський державний медичний університет, 2024-03-20) Steblovskyi, D. V.; Kopchak, A. V.; Lokes, K. P.; Bilokon, S. O.; Voloshyna, L. I.; Popovych, I. Yu.; Стебловський, Дмитро Валерійович; Копчак, А. В.; Локес, Катерина Петрівна; Білокінь, Сергій Олександрович; Волошина, Людмила Іванівна; Попович, Іван ЮрійовичAccording to domestic and foreign authors, the incidence of chronic sinusitis has increased more than 2 times over the past 10 years, and the specific weight of patients hospitalized in ENT – inpatients increases annually by 1.5-2% and has no tendency to decrease. Such information, apparently, is due not to the true ratio of sinusitis of various etiologies, but to the peculiarity of the examination of patients with this pathology in dental and otorhinolaryngological hospitals. The peak of admissions of patients with odontogenic sinusitis to the Department of Maxillofacial Surgery of Poltava Regional Clinical Hospital occurred in 2019 – 272 (16.7%) cases of sinusitis, the lowest rate of hospitalization was recorded in 2008 – 195 (about 11.9%). The most common diagnosis was: “Exacerbation of chronic odontogenic sinusitis” – 817 (50.2%) cases, which is consistent with the literature data. Patients with the diagnosis: “Acute odontogenic sinusitis” accounted for the minimum rate – 2.4% of cases. Recurrence of sinusitis was observed on average in 2017-2023 in 5.2% of cases. In 19.3% of cases, there was a discrepancy between the diagnosis of the referring institution and the clinical diagnosis. In 2.6% of cases, the clinical diagnosis did not correspond to the described clinical data. 59.2% of patients were referred from dental polyclinics and offices; 15.7% of patients were referred by related specialists (ENT, neurologist); 14.7% went to the hospital themselves; in 10% of cases, data on the sending institution were missing. The problem of prevention, diagnosis (including differential) and treatment of odontogenic sinusitis is an urgent task of dentistry. Among the causes of the development of the disease, a significant part is pathological processes, the development of which was facilitated by inadequate medical tactics for the treatment of chronic inflammatory processes in the area of molars of the upper jaw. The use of traditional methods of radical surgical treatment is often accompanied by chronicity of the process.Документ Problem education as the key of the formation of a future stomatologist(Полтавський державний медичний університет, 2023-12-22) Локес, Катерина Петрівна; Розколупа, Олександр Олексійович; Ставицький, Станіслав Олександрович; Торопов, Олександр Анатолійович; Білоконь, Сергій Олександрович; Аветіков, Давид Соломонович; Lokes, K. P.; Rozkolupa, O. O.; Stavytskyi, S. O.; Toropov, O. A.; Bilokon, S. O.; Avetikov, D. S.Необхідною складовою підготовки майбутнього лікаря-стоматолога на сучасному етапі є використання проблемного навчання, яке повинно зосереджуватися на пріоритетних проблемах охорони здоров’я та відповідати освітньо-професійній програмі та навчальному плану дисципліни, що викладається. Мета дослідження – визначити оптимальні методи навчання, які на сучасному етапі можуть бути застосовані на стоматологічних факультетах. На кафедрі хірургічної стоматології та щелепно-лицевої хірургії постійно приділяється увага впровадженню нових методів у навчальний процес. Особливу увагу слід звернути на розкриття рідкісних клінічних випадків, які можуть трапитися у подальшій практиці лікаря-стоматолога, оскільки дана категорія пацієнтів не є типовою, а також часто буває незрозумілою для молодого спеціаліста, що може оказати негативний вплив на надання стоматологічної допомоги такому хворому.Документ Provision of urgent assistance to children with traumatic injuries of the soft tissues of the maxillo-facial region(Wydawnictwo Aluna, 2023) Tkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Dolenko, О. В.; Popelo, Yu. V.; Korotych, N. M.; Rezvina, K. Iu.; Hohol, Ya. A.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Доленко, Ольга Борисівна; Попело, Юлія Вікторівна; Коротич, Наталія Миколаївна; Резвіна, Катерина Юріївна; Гоголь, Андрій МихайловичВид та обсяг лікувальних заходів у дітей з травматичним ушкодженням м’яких тканин в значній мірі залежить від виду і характеру травмуючого агента. Найчастіше дитячому хірургу-стоматологу доводиться мати справу з ранами, які характеризуються порушенням цілісності м’яких тканин і які мають індивідуальні особливості, що слід враховувати при проведенні їх первинної хірургічної обробки та визначені обсягу медичного супроводу в ранньому післяопераційному періоді.Документ Results of complex treatment of maxillofacial hemangiomas in children(Полтавський державний медичний університет, 2022) Tkachenko, P. I.; Bilokon, S. O.; Lokhmatova, N. M.; Popelo, Y. V.; Dolenko, O. B.; Korotych, N. M.; Bilokon, N. P.; Ткаченко, Павло Іванович; Білоконь, Сергій Олександрович; Лохматова, Наталія Михайлівна; Попело, Юлія Вікторівна; Доленко, Ольга Борисівна; Коротич, Наталія Миколаївна; Білоконь, Наталія ПавлівнаЗа останні роки частота виявлення гемангіом щелепно-лицевої ділянки у дітей в Україні значно збільшилась. З метою визначення ефективності їх комплексного лікування узагальнено зміст 32 стаціонарних історій хвороб та 47 амбулаторних карт тематичних дітей. Капілярні гемангіоми діагностовано у 20 % випадків (у 19 % у вигляді винних плям). В 25 % спостережень вони самостійно редукувалися протягом 7-12 місяців. Незначні за обсягом і глибиною пухлини (56 % випадків) ліквідовано діатермокоагуляцією чи місцевим введенням малих доз преднізолону. Для усунення «великих плям» застосовувалась фракційна лазеротерапія. Кавернозні гемангіоми діагностовано в 23 % випадків. У 72 % пацієнтів проведено лікування дипроспаном у вигляді чотирьохразової інфільтрації по периферії утворення. У 23 % спостережень проводилось черезшкірне прошивання пухлини, пункція новоутворення з подальшим введенням в порожнини 70 % розчину спирту. Змішані гемангіоми (46 % пацієнтів) лікували застосуванням анаприліну. У 33 % пацієнтів піогенну гранульому видалено радикальним хірургічним втручанням, а у 67 % – діатермокоагуляцією. По завершенню лікування гемангіом всі діти пройшли курс реабілітаційних заходів.
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