Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors
Ескіз недоступний
Дата
2019
Назва журналу
Номер ISSN
Назва тому
Видавець
Wydawnictwo Aluna
Анотація
Introduction: According to modern standards of treatment of malignant neoplasms conducting polychemotherapy requires up to 90% of cancer patients. However, in addition to the expected cytotoxic effects, it is accompanied by disorders in dental health in the vast majority of patients.
The aim: To study the effect of cytostatics on soft tissues of the oral cavity in children with malignant tumors of the abdominal cavity.
Materials and methods: Material for writing this scientific work served as a synthesis of results for 25 people aged 7 to 15 years with malignant tumors of the abdominal cavity, in which a comprehensive oral examination was performed to determine the manifestations of dental toxicity cytostatics.
Results: At the end of the first course of chemotherapy, all patients had dry redness of the lips, 20 - (80,0%) with eruptions, in 18 - (20,0%) erosion. The Green-Vermillion, PMA, and PBI indices grew by 1,8; 7 and 3,3 times respectively. In cytograms with buccal epithelium an increase in the number of cells of polymorphic sizes and forms with signs of gidropic dystrophy was found. The nuclear-cytoplasmic ratio decreased by 1,4 times compared with the primary examination.
Conclusions: This situation creates the preconditions for the development of inflammatory process in the tissues of the oral cavity and requires the use in this category of patients of a substantiated pathogenetic correction of existing disorders.
Опис
Ключові слова
children, malignant tumors, abdominal cavity, oral cavity, polychemotherapy
Бібліографічний опис
Popelo Yu. V. Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors / Yu. V. Popelo, P. I. Tkachenko, S. O. Bilokon // Wiadomosci Lekarskie. – 2019. – T. LXXІІ, nr 5, cz. II. – С. 978–982.