Перегляд за Автор "Khattou, V. V."

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    Characteristics of bone defect replacement methods and controlled bone regeneration: a comparative study
    (Полтавський державний медичний університет, 2023) Khattou, V. V.; Хатту, Вікторія Віталіївна
    The search for methods of influence on reparative osteogenesis is an urgent issue today in modern dentistry. Over the past decade, significant progress has been made in solving this problem in scientific research and clinical practice. The goal of our study was to find effective osteoregenerative drugs for the elimination of jaw defects. A search and analysis of professional publications on the specified issue were carried out in library sources and search engines, particularly PubMed and Google Scholar. The aesthetic appearance of a modern person's smile has now become a necessary aspect of social adaptation in society, which determines the importance of such a problem today as secondary adentia, which is formed as a result of tooth extraction. Timely replacement of defects in such patients has a lot of advantages for a person, and dental implantation has become a modern alternative to other types of removable and non-removable prosthetics, which determines the normalization of the chewing and digestive process and optimization of aesthetics. But the vertical and horizontal atrophy of the alveolar process, which occurs after tooth extraction, can create negative prerequisites for the surgical stage of dental implantation and requires additional surgical interventions. Summarizing the scientific literature data, it can be stated that the use of innovative technologies for filling bone defects with osteoplastic materials capable of managing the restoration of the structure and function of bone tissue ensures stable dental rehabilitation of patients.
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    Dynamics of bone formation and osteoresorption markers in patients with postoperative mandibular bone defects
    (Полтавський державний медичний університет, 2023-12) Khattou, V. V.; Ivanytska, O. S.; Havryliev, V. M.; Buhanchenko, O. P.; Boyko, I. V.; Lokes, K. P.; Avetikov, D. S.; Хатту, Вікторія Віталіївна; Іваницька, Олена Сергіївна; Гаврильєв, Віктор Миколайович; Буханченко, Ольга Петрівна; Бойко, Ігор Васильович; Локес, Катерина Петрівна; Аветіков, Давид Соломонович
    The defect that appears after a tooth extraction leads to remodeling of bone tissue. The processes of remodeling and mineralization of the newly formed bone are affected by substances with an antioxidant effect, among which are quercetin and placenta cryoextract. The study involved 90 procedures in which tooth extraction was performed: using placenta cryoextract (group 1), combination of placenta cryoextract with quercetin (group 2) and standard treatment protocol (group 3). The content of osteocalcin and matrix metalloproteinase-8 in blood serum was determined. The formation of a postoperative defect in bone tissue was accompanied by antagonistic changes in the content of osteocalcin (due to its increase) and MMP-8 (due to its decrease) in the blood serum and oral fluid of patients, which characterizes the activation of bone tissue resorption processes at earlier times and bone formation at later times.