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Документ Hepatitis A. the features of disease course in adults(Wiadomosci lekarskie (Warsaw, Poland), 2023) Pryimenko, Nataliia; Koval, Tetiana; Kotelevska, Tetiana; Bodnar, Vadym; Syzova, Liudmyla; Marchenko, Olena; Прийменко, Наталія Олегівна; Коваль, Тетяна Ігорівна; Котелевська, Тетяна Михайлівна; Боднар, Вадим Анатолійович; Сизова, Людмила Михайлівна; Марченко, Олена ГеннадіївнаObjective: The aim: To analyze the incidence of Hepatitis A in Ukraine and Poltava region and to study the clinical and epidemiological features of the course of Hepatitis A in adult patients. Patients and methods: Materials and methods: The course of HA in 96 hospitalized patients was analyzed. The diagnosis of HA was established on the basis of clinical and epide¬miological data and confirmed by the results of laboratory studies (serological and molecular biological). Results: Results: In 2019, in the Poltava region, there was an increase in the incidence of Hepatitis A with a predominance among sick people of working age, among the urban population. This part of people aged from 60 to 75 years old constitutes 9.4%. This study showed that the waterway was the dominant way of HA transmission. The course of the disease in most hospitalized patients was typical and cyclic, with a predominance of a mixed variant of the pre-jaundice period and jaundice. One third of patients survey that they had fever, which persisted with jaundice. Conclusion: Conclusions: The findings of this study indicates that the patients older than 40 years were more likely to have concomitant chronic pathology than younger patients, and Hepatitis A was more severe with the development of prolonged cholestasis, wave-like course and recurrence. In most patients under the age of 40, the course of Hepatitis A was mild, but splenomegaly and severe cytolytic syndrome were more common.Документ Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine(The Lancet HIV, 2022) Vasylyev, Marta; Skrzat-Klapaczyńska, Agata; Bernardino, Jose; Săndulescu, Oana; Gilles, Christine; Libois, Agnès; Curran, Adrian; Spinner, Christoph; Rowley, Dominic; Bickel, Markus; Aichelburg, Maximilian; Nozza, Silvia; Wensing, Annemarie; Barber, Tristan; Waters, Laura; Jordans, Carlijn; Bramer, Wichor; Lakatos, Botond; Tovba, Lidia; Koval, Tetiana; Kyrychenko, Tetyana; Dumchev, Kostyantyn; Buhiichyk, Vira; Smyrnov, Pavlo; Antoniak, Svitlana; Antoniak, Sergii; Vasylyeva, Tetyana; Mazhnaya, Alyona; Kowalska, Justyna; Bhagani, Sanjay; Rokx, Casper; Коваль, Тетяна Ігорівна; Кириченко, Тетяна СтаніславівнаUkraine is one of the countries in Europe most affected by HIV. The escalation of open war on the European continent has affected HIV care in Ukraine in an unprecedented way. Treating physicians in Europe have little experience on how to handle HIV-specific care under these circumstances. A framework is urgently needed that both defines and sets out strategies to handle the specific challenges for emergency support for people living with HIV, both those staying in Ukraine and those becoming displaced. The optimal allocation of the few available medical resources, primarily antiretroviral therapy, is necessary to best prevent individual morbidity and achieve population transmission control. Professional HIV networks play a central role to create, optimise, and execute support strategies. Through a rapid literature review we identified the key strategies needed to create a support framework, adapted to Ukraine’s HIV epidemiology. We produce a unified support framework aiming to reduce the inevitable impact on Ukraine’s HIV care cascade now, and when rebuilding it after the war.