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Документ Expression of periferal core molecular clock genes in oral mucosa depends on the chronotype in patients with maxillofacial cellulitis(Journal of Oral Biology and Craniofacial Research, 2023-09) Lokes, Kateryna; Lychman, Vitaliy; Izmailova, Olga; Shlykova, Oksana; Avetikov, David; Kaidashev, Igor; Локес, Катерина Петрівна; Личман, Віталій Олександрович; Ізмайлова, Ольга Віталіївна; Шликова, Оксана Анатоліївна; Аветіков, Давид Соломонович; Кайдашев, Ігор ПетровичIntroduction: Accurate determination of the patient’s chronotype is one of the problems of personalized medicine. Recent studies have shown that determining of the expression of timing genes is a valuable method that can help gain molecular insight into a patient’s intrinsic circadian timing. Odontogenic cellulitis is very common pathology. Since acute inflammatory diseases are an urgent pathology, the time of surgical intervention can correspond depend on the time of the patient’s hospitalization. Materials and methods: The level of mRNA expression of peripheral circadian clock genes clock and bmal1, per1, cry1 in buccal epithelial cells in patients with odontogenic purulent inflammatory diseases of maxillofacial area in the morning and evening was investigated.Документ Microbiological substantiation of the effectiveness of quercitin and its combination with ethylmethylhydroxypyridine succinate in the complex treatment of odontogenic phlegmon and maxillofacial abscesses(2024-01-19) Lokes, Kateryna; Kiptilyi, Anatolii; Skikevych, Margaryta; Steblovskyi, Dmytro; Lychman, Vitaliy; Bilokon, Serhii; Avetikov, David; Локес, Катерина Петрівна; Кіптілий, Анатолій Васильович; Скікевич, Маргарита Георгіївна; Стебловський, Дмитро Валерійович; Личман, Віталій Олександрович; Білоконь, Сергій Олександрович; Аветіков, Давид СоломоновичOdontogenic infections can become life-threatening. The aim of the study was to determine the effectiveness of quercitin and its combination with ethylmethylhydroxypyridine succinate in the complex treatment of odontogenic infections by assessing the microbial population of the infection site