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Документ Peculiarities of diabetes mellitus impact on the effectiveness of cardiac rehabilitation of patients with coronary heart disease after myocardial revascularization(Aluna Publishing, 2023) Teslenko, Yu. V.; Pysana, B. O.; Teslenko, M. M.; Dubrovinska, T. V.; Bilash, S. M.; Lyulka, N. O.; Тесленко, Юрій Віталійович; Писана, Богдана Олександрівна; Тесленко, Марина Миколаївна; Дубровінська, Тетяна Володимирівна; Білаш, Сергій Михайлович; Люлька, Надія ОлександрівнаAim: To investigate the impact of diabetes mellitus on the course of the disease, the quality of rehabilitation measures and the psycho-emotional state of patients. Materials and Methods: The study involved 134 patients, who were divided into four groups depending on the method of revascularization and the presence or absence of diabetes mellitus. The patients underwent a 21-day rehabilitation programme, at the beginning and at the end of which they were assessed for left ventricular ejection fraction, exercise tolerance, maximum oxygen consumption, and treatment adherence. Throughout the study, the patients were under the supervision of a psychologist. Results: The study found that patients with diabetes showed a significant improvement in the measured indicators, but to a lesser extent than patients without diabetes. Conclusions: The mechanisms of poorer outcomes in patients with diabetes are mostly related to psycho-emotional factors as a result of the diagnosed disease, but they require further study.Документ Rhythm control in patients with bradyasystolic atrial fibrillation(Полтавський державний медичний університет, 2023) Miakinkova, L. O.; Liulka, Ye. M.; Katerenchuk, I. P.; Teslenko, Y. V.; Pysana, B. O.; М'якінькова, Людмила Олександрівна; Люлька, Євген Миколайович; Катеренчук, Іван Петрович; Тесленко, Юрій Віталійович; Писана, Б.О.Atrial fibrillation is the most common cardiac arrhythmia associated with thromboembolism, heart failure, depression, deterioration of quality of life, and reduced physical endurance. The rhythm control strategy is considered optimal in its treatment but is not always achievable. Right ventricular endocardial pacing is recommended for patients with bradycardic atrial fibrillation and preserved ejection fraction but can cause ventricular dyssynchrony. The aim of the study was to evaluate the effectiveness of implanting a dual-chamber pacemaker as an alternative method for sinus rhythm control in patients with long-standing bradysystolic atrial fibrillation and preserved ejection fraction, compared with single-chamber right ventricular pacing. Diastolic function, left atrial volume index, exercise tolerance, and quality of life were studied. Dual-chamber pacing is effective in rhythm control, and the severity of symptoms is reduced. Compared with single-chamber right ventricular pacing, there were decreased left atrial volume, tricuspid regurgitation rate, natriuretic peptide levels, increased exercise tolerance, improved quality of life indices, and reduced anxiety and depression. Key words: atrial fibrillation, heartДокумент Рrevention of contrast-induced nephropathy during interventional treatment of acute coronary syndrome(Дніпровський державний медичний університет, 2023-12-22) Miakinkova, L. O.; Yarmola, T. I.; Pustovoit, G. L.; Kostrikova, Iu. A.; Pysana, B. O.; Talash, V. V.; М'якінькова, Людмила Олександрівна; Ярмола, Тетяна Іванівна; Пустовойт, Ганна Леонідівна; Кострікова, Юлія Анатоліївна; Писана, Богдана Олександрівна; Талаш, Вікторія ВолодимирівнаThe aim of the work was to determine the risk factors of contrast-induced nephropathy in patients with acute coronary syndrome and to evaluate the effectiveness of methods of its prevention. There were examined 62 patients admitted to the interventional cardiology department during 9 months of routine practice with a diagnosis of acute coronary syndrome and concomitant chronic kidney disease. Among them, 56.45% have diabetic nephropathy, 21% – hypertensive nephropathy, 19.35% – chronic pyelonephritis, 3.2% – gouty nephropathy. According to the stages of chronic kidney disease: I stage – 8.1%, II stage – 46.8%, III A stage – 30.6%, III B stage – 14.5% of patients. The control group consisted of 32 patients with acute coronary syndrome without kidney pathology. All patients underwent urgent percutaneous coronary intervention with a water-soluble low-osmolarity radiocontrast medium. The risk of contrast-induced nephropathy was determined according to the Mehran scale. Contrast-induced nephropathy was diagnosed by an increase in serum creatinine by 25% over 24-48 hours. Prevention of contrast-induced nephropathy according to existing recommendations was carried out by prescribing early statin therapy and diuresis-controlled combined hydration in 22 patients with concomitant chronic kidney disease. Mathematical processing was performed using Statistica 8.0 software (StatSoft Inc, USA). Patients with chronic kidney disease had a high and very high risk of contrastinduced nephropathy in 19.4% and 3.2% of cases, among them in 91.6% high, and in 100% – very high-risk contrastinduced nephropathy developed. Patients in the control group had a low to moderate risk, none of them developed contrast-induced nephropathy. It has been shown that the risk of contrast-induced nephropathy depends on the stage of chronic kidney disease and is associated with a decrease in the ejection fraction of the left ventricle (≤40%), acute left ventricle failure of the III and IV classes according to Killip, a decrease in diuresis up to ≤0.6 ml/h/kg in the first 12- 24 hours after urgent percutaneous coronary intervention; taking metformin 6-12 hours before the administration of the X-ray contrast medium and the glomerular filtration rate ≤45 ml/min./1.73 m2. In patients who underwent prevention of contrast-induced nephropathy in its entirety, its development was not registered.