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Документ A case report of a rare course of secondary chronic odontogenic osteomyelitis of the upper jaw in a young patient(Frontiers of Oral and Maxillofacial Medicine, 2023-03-15) Skrypnyk, Maksym; Skikevych, Margarita; Petrushanko, Tatiana; Скрипник, Максим Ігорович; Скікевич, Маргарита Георгіївна; Петрушанко, Тетяна ОлексіївнаChronic jaw osteomyelitis is an inflammatory disease of the entire bone which results in jaw destruction and sequestrum formation, usually it`s more common in the lower jaw. Only a few clinical cases have documented the development of chronic odontogenic osteomyelitis on the upper jaw that is why the clinical course of the disease is variable and not typical in different patients. A quite rare variant of chronic maxilla osteomyelitis manifestation in a healthy young individual that was undiagnosed for a long time is presented in this case report.Документ Changes in the periodontium against the background of systemic vascular reactions in young individuals with obesity(Wroclaw Medical University, Poland / Вроцлавський медичний університет, Польща, 2023) Skrypnyk, Maksym; Petrushanko, Tatiana; Neporada, Karine; Petrushanko, Vladymyr; Skrypnyk, Igor; Скрипник, Максим Ігоревич; Петрушанко, Тетяна Олексіївна; Непорада, Каріне Степанівна; Петрушанко, Володимир Миколайович; Скрипник, Ігор МиколайовичBackground. Overweight and obesity are defined as abnormal or excessive fat accumulation that impairs health. The global prevalence of obesity has been increasing significantly among all age groups. Furthermore, obesity is a comorbid factor for numerous diseases, including cardiovascular and periodontal pathologies. Objectives. The present study aimed to investigate the influence of overweight and obesity on the periodontium of young adults in relation to the functional state of the cardiovascular system. Material and methods. The oral health status of 132 males and females aged 18–22 years was examined. They were divided into 4 groups according to their body mass index (BMI): normal weight; overweight; class I obesity; and class II obesity. A periodontal chart, the records on oral hygiene and caries, and periodontal indices were provided for each participant. The main functional parameters of the cardiovascular system were measured before and after the dental examination. Results. Overweight or obesity did not affect the intensity of caries in young adults. The prevalence and severity of gingivitis were significantly higher in obese individuals. A moderate correlation was found between gingivitis and BMI in patients with class I and II obesity. Disturbances in the cardiovascular system function and in the autonomic nervous system tone were also diagnosed in obese patients. An impaired vascular response and significant functional changes in the cardiovascular system developed against the background of obesity. These changes show the development of subcompensation in young adults with obesity. Conclusions. In obese individuals, significantly worse oral hygiene was observed as compared to normalBMI patients. Moreover, the clinical manifestation and intensity of gingivitis in obese individuals were high even in those with satisfactory oral hygiene. In young obese individuals, the periodontal disease manifested as gingivitis is due to significant adaptive and compensatory mechanisms.Документ Clinical performance of "free-hand" direct composite crowns used for the restoration of severely destroyed mandibular molars(Polish Dental Association / Польська асоціація стоматологів / http://www.jstoma.com, 2023) Skrypnyk, Maksym; Petrushanko, Tatiana; Скрипник, Максим Ігорович; Петрушанко, Тетяна ОлексіївнаIntroduction: There are several restorative approaches for the restoration of severely destroyed teeth, each with its own advantages and disadvantages. Objectives: This study aimed to evaluate the clinical performance of direct composite resin crowns used for restoration of severely destroyed mandibular molars in young patients. Material and methods: In total 45 severely destroyed vital and non-vital mandibular molars were restored in 44 patients (24-40 years old). Mandibular molars were restored in a “free-hand” direct restoration approach us-ing a biomimetic concept (4-layer technic). After the restoration, on the 3rd- and 6th-month, and the 1st-, 2nd-, and 3rd-year follow-ups, the clinical performance of the restoration was evaluated. During the follow-ups, the integrity of restoration, contact point stability, dental plaque accumulation, and gingival bleeding indices were evaluated, and restoration survival was accessed. Results: Restorations showed up to 100% survival after 3 years of exploitation. Significantly, lower gingival bleeding and plague accumulation index were registered during the follow-up visits after the restoration, which is a sign of good integration of the restoration into the bite. Only one case of partial fracture of the restoration occurred, which was repaired with composite resin. No differences between the clinical performance in non-vital and vital mandibular molars were observed. Conclusions: “Free-hand” direct composite crowns used for the restoration of severely destroyed mandibular molars showed promising results for the restoration of severely destroyed mandibular molars in a 3-year obser-vation period.Документ Colonization resistance of oral mucosa in individuals with diverse body mass index(Polish Dental Association / Польська асоціація стоматологів, 2022) Skrypnyk, Maksym; Petrushanko, Tatiana; Neporada, Karine; Vynnyk, Nataliia; Petrushanko, Vladymyr; Skrypnyk, Roman; Скрипник, Максим Ігорович; Петрушанко, Тетяна Олексіївна; Непорада, Каріне Степанівна; Винник, Наталія Іванівна; Петрушанко, Володимир Миколайович; Скрипник, Роман ІгоровичIntroduction: Colonization resistance oftheoral cavity is animportant protective factor oflocal immunity, which prevents theadhesion and proliferation ofmicroorganisms on theoral mucosa. Objectives: Theresearch aimed to discover thecolonization resistance state oftheoral mucosa ofyoung patients with different body mass indices and their dependence on theintensity oftheteeth carious and inflammatory response ofthegums. Material and methods: Thesurvey conducted on 132 Ukrainians ofall genders, with aged ranging from 18 to 22 years. Body mass index (BMI) was determined, which was thedistribution factor. Oral status was detected by decay, missing, and filled teeth (DMFT) index, oral hygiene index (OHI) and papilla bleeding index (PBI) determination. Colonization resistance oftheoral mucosa was defined by microscopy ofthebuccal epithelium using alight microscope with amagnification of×400. Results: 21.2% ofpatients with normal BMI had colonization resistance index (CRI) 0, 78.8% – CRI 1. In patients with extra weight, 44.5% had CRI 0, 38.9% – CRI 1, 16.6 – CRI 2. In patients with 1st degree obesity, 64.5% had CRI 0, 25.8% – CRI 1, 9.7% – CRI 2. In patients with 2nd degree obesity, 68.75% presented CRI 0, 31.25% – CRI 1. Conclusions: With satisfactory oral hygiene in patients with diverse BMI theseverity ofgingivitis was different. This indicates that thesystemic response oftheorganism in patients with BMI over 30 kg/m2 is thecrucial determining factor that influences themanifestation ofthedisease, as aresponse to local pathogenic factor – dental plaque. Therefore, in patients with 1st and 2nd degree obesity, in 70% ofpatients, suppression ofcolonization resistance oftheoral mucosa was observed, compared with patients with normal BMI where thefrequency ofpatients with colonization resistance disturbance was 2.5 times lower.Документ Dependence of the Dental Status of Young Individuals with Different Body Weights on their Eating Behavior(Faculty of Medicine Nis, 2022) Skrypnyk, Maksym; Petrushanko, Tatiana; Neporada, Karine; Skrypnyk, Roman; Petrushanko, Vladymyr; Skrypnyk, Igor; Скрипник, Максим Ігорович; Петрушанко, Тетяна Олексіївна; Непорада, Каріне Степанівна; Скрипник, Роман Ігорович; Петрушанко, Володимир Миколайович; Скрипник, Ігор МиколайовичObesity is a global problem of modern society. According to the WHO, in 2016, more than 1.9 billion adults are overweight and about 650 million adults are obese. Numerous studies indicate the role of overweight, obesity and metabolic status on periodontal health, however, the mechanism of their development is not fully understood. The aim of the study was to explore the mechanism of periodontal disease development in patients with diverse body mass index and the mechanism of extra weight and obesity onset in these patients. The study involved 132 Ukrainian males and females, 18 - 22 years old. Body mass index was determined in all patients. Information on life history, illness and family history was collected. The assessment of dental status was conducted by indicating the oral and tongue hygiene indices and periodontal indices. Eating behaviour was assessed using the standardised Dutch eating behaviour questionnaire (DEBG) and the three-factor eating questionnaire (TFEQ R-18). Diet assessment was determined by standardized diet questionnaire. More than 60% of young people with the 1st and 2nd degree obesity had eating disorders, the most prevalent were disturbance of cognitive restraint and emotional eating components of eating behavior. The prevalence of periodontal disease was significantly higher in obese individuals, up to 87% in patients with the 1st and 2nd degree obesity. Eating behavior disturbances play a crucial role in the development of obesity in young adults and onset of gingivitis. The cause of non-plaque-induced gingivitis in patients with the 1st and 2nd degree obesity is a impaired general host response to the pathogenic factors of the oral cavity, caused by excess adipose tissue, which led to the development of chronic systemic mild inflammation. That is why these patients need a specific, integrated periodontal treatment.Документ Пародонтологічний статус осіб молодого віку з ожирінням(Видавець: Сергій Радлінський, 2024) Скрипник, Максим Ігорович; Петрушанко, Тетяна Олексіївна; Skrypnyk, Maksym; Petrushanko, TatianaОстаннім часом збільшилася поширеність ожиріння, і особливо значущим є його зростання в осіб молодого віку. На сьогодні взаємозв’язок ожиріння і пародонтиту є визнаним у дорослих, хоча достеменно не відомі особливості виникнення і розвитку початкових стадій захворювань пародонта в осіб молодого віку, що дало б змогу розробити ефективну стратегію їх профілактики та лікування. Нами проведене комплексне клінічне, антропометричне обстеження 132 осіб молодого віку (18–22 роки) з різним значенням індексу маси тіла. Виявлено, що обстежені із I та II ступенем ожиріння мали більшу поширеність і тяжчий перебіг захворювань пародонта, ніж особи з нормальною масою тіла. У статті зроблено огляд наукової літератури, що аналізує ефективність різних підходів до лікування захворювань пародонта в осіб з ожирінням. Recently, the prevalence of obesity has increased significantly, especially among young adults. Nowadays, the relationship between obesity and periodontitis is recog-nized in adults, however, peculiarities of periodontal disease development in young adults are not yet clear, that would make it possible to design an effective strategy for periodontal disease prevention and treatment. We conducted a comprehensive clinical and anthropometric examination of 132 young adults (18-22 years old) with different body mass index. We found that youngsters with I and II degrees of obesity had a higher prevalence and severity of periodontal disease than those one with normal body weight. We also reviewed the literature on the effectiveness of various treat-ment methods of periodontal disease in obese individuals.