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Документ Colonization resistance of oral mucosa in individuals with diverse body mass index(Polish Dental Association / Польська асоціація стоматологів, 2022) Skrypnyk, Maksym; Petrushanko, Tatiana; Neporada, Karine; Vynnyk, Nataliia; Petrushanko, Vladymyr; Skrypnyk, Roman; Скрипник, Максим Ігорович; Петрушанко, Тетяна Олексіївна; Непорада, Каріне Степанівна; Винник, Наталія Іванівна; Петрушанко, Володимир Миколайович; Скрипник, Роман ІгоровичIntroduction: Colonization resistance oftheoral cavity is animportant protective factor oflocal immunity, which prevents theadhesion and proliferation ofmicroorganisms on theoral mucosa. Objectives: Theresearch aimed to discover thecolonization resistance state oftheoral mucosa ofyoung patients with different body mass indices and their dependence on theintensity oftheteeth carious and inflammatory response ofthegums. Material and methods: Thesurvey conducted on 132 Ukrainians ofall genders, with aged ranging from 18 to 22 years. Body mass index (BMI) was determined, which was thedistribution factor. Oral status was detected by decay, missing, and filled teeth (DMFT) index, oral hygiene index (OHI) and papilla bleeding index (PBI) determination. Colonization resistance oftheoral mucosa was defined by microscopy ofthebuccal epithelium using alight microscope with amagnification of×400. Results: 21.2% ofpatients with normal BMI had colonization resistance index (CRI) 0, 78.8% – CRI 1. In patients with extra weight, 44.5% had CRI 0, 38.9% – CRI 1, 16.6 – CRI 2. In patients with 1st degree obesity, 64.5% had CRI 0, 25.8% – CRI 1, 9.7% – CRI 2. In patients with 2nd degree obesity, 68.75% presented CRI 0, 31.25% – CRI 1. Conclusions: With satisfactory oral hygiene in patients with diverse BMI theseverity ofgingivitis was different. This indicates that thesystemic response oftheorganism in patients with BMI over 30 kg/m2 is thecrucial determining factor that influences themanifestation ofthedisease, as aresponse to local pathogenic factor – dental plaque. Therefore, in patients with 1st and 2nd degree obesity, in 70% ofpatients, suppression ofcolonization resistance oftheoral mucosa was observed, compared with patients with normal BMI where thefrequency ofpatients with colonization resistance disturbance was 2.5 times lower.Документ Dependence of the Dental Status of Young Individuals with Different Body Weights on their Eating Behavior(Faculty of Medicine Nis, 2022) Skrypnyk, Maksym; Petrushanko, Tatiana; Neporada, Karine; Skrypnyk, Roman; Petrushanko, Vladymyr; Skrypnyk, Igor; Скрипник, Максим Ігорович; Петрушанко, Тетяна Олексіївна; Непорада, Каріне Степанівна; Скрипник, Роман Ігорович; Петрушанко, Володимир Миколайович; Скрипник, Ігор МиколайовичObesity is a global problem of modern society. According to the WHO, in 2016, more than 1.9 billion adults are overweight and about 650 million adults are obese. Numerous studies indicate the role of overweight, obesity and metabolic status on periodontal health, however, the mechanism of their development is not fully understood. The aim of the study was to explore the mechanism of periodontal disease development in patients with diverse body mass index and the mechanism of extra weight and obesity onset in these patients. The study involved 132 Ukrainian males and females, 18 - 22 years old. Body mass index was determined in all patients. Information on life history, illness and family history was collected. The assessment of dental status was conducted by indicating the oral and tongue hygiene indices and periodontal indices. Eating behaviour was assessed using the standardised Dutch eating behaviour questionnaire (DEBG) and the three-factor eating questionnaire (TFEQ R-18). Diet assessment was determined by standardized diet questionnaire. More than 60% of young people with the 1st and 2nd degree obesity had eating disorders, the most prevalent were disturbance of cognitive restraint and emotional eating components of eating behavior. The prevalence of periodontal disease was significantly higher in obese individuals, up to 87% in patients with the 1st and 2nd degree obesity. Eating behavior disturbances play a crucial role in the development of obesity in young adults and onset of gingivitis. The cause of non-plaque-induced gingivitis in patients with the 1st and 2nd degree obesity is a impaired general host response to the pathogenic factors of the oral cavity, caused by excess adipose tissue, which led to the development of chronic systemic mild inflammation. That is why these patients need a specific, integrated periodontal treatment.