Skull plasmacytomas: a rare manifestation of multiple myeloma

Abstract

Introduction: Recently, the incidence of plasma cell neoplastic disorders has been growing rapidly in Ukraine as well as all over the world, which may be due to prominent advances in diagnosis. One of the most common plasma cell neoplasms is multiple myeloma (MM). Myeloma is a master of camouflage, has thousands of masks and can be presented with different symptoms: anemia, lytic bone lesions, bone fractures, renal failure and quite often soft tissue tumor growths, called extramedullary plasmacytomas. That’s why every case of this disease is unique. We would like to present you a rare case of MM which clinically presented with several large plasmacytomas of the skull. Case history: A 65-year-old male was referred to Hematology department of Poltava Regional Clinical Hospital n. a. M.V. Sklifosovsky with a history of multiple slow growing cranial masses. Patient noticed their appearance 3 month before, but as they were painless didn’t pay much attention. Two weeks ago the patient developed nausea, dizziness, severe general weakness, that made him to go to his family doctor, who after brief examination sent patient to hematologist.