Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors

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dc.contributor.authorPopelo, Yu. V.
dc.contributor.authorTkachenko, P. I.
dc.contributor.authorBilokon, S. O.
dc.contributor.authorПопело, Юлія Вікторівна
dc.contributor.authorТкаченко, Павло Іванович
dc.contributor.authorБілоконь, Сергій Олександрович
dc.date.accessioned2020-01-13T06:37:03Z
dc.date.available2020-01-13T06:37:03Z
dc.date.issued2019
dc.description.abstractIntroduction: According to modern standards of treatment of malignant neoplasms conducting polychemotherapy requires up to 90% of cancer patients. However, in addition to the expected cytotoxic effects, it is accompanied by disorders in dental health in the vast majority of patients. The aim: To study the effect of cytostatics on soft tissues of the oral cavity in children with malignant tumors of the abdominal cavity. Materials and methods: Material for writing this scientific work served as a synthesis of results for 25 people aged 7 to 15 years with malignant tumors of the abdominal cavity, in which a comprehensive oral examination was performed to determine the manifestations of dental toxicity cytostatics. Results: At the end of the first course of chemotherapy, all patients had dry redness of the lips, 20 - (80,0%) with eruptions, in 18 - (20,0%) erosion. The Green-Vermillion, PMA, and PBI indices grew by 1,8; 7 and 3,3 times respectively. In cytograms with buccal epithelium an increase in the number of cells of polymorphic sizes and forms with signs of gidropic dystrophy was found. The nuclear-cytoplasmic ratio decreased by 1,4 times compared with the primary examination. Conclusions: This situation creates the preconditions for the development of inflammatory process in the tissues of the oral cavity and requires the use in this category of patients of a substantiated pathogenetic correction of existing disorders.uk_UA
dc.identifier.citationPopelo Yu. V. Impact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumors / Yu. V. Popelo, P. I. Tkachenko, S. O. Bilokon // Wiadomosci Lekarskie. – 2019. – T. LXXІІ, nr 5, cz. II. – С. 978–982.uk_UA
dc.identifier.issnISSN 0043-5147
dc.identifier.urihttps://repository.pdmu.edu.ua/handle/123456789/11662
dc.language.isoenuk_UA
dc.publisherWydawnictwo Alunauk_UA
dc.subjectchildrenuk_UA
dc.subjectmalignant tumorsuk_UA
dc.subjectabdominal cavityuk_UA
dc.subjectoral cavityuk_UA
dc.subjectpolychemotherapyuk_UA
dc.titleImpact of polychemotherapy on the oral soft tissues in children with malignant abdominal tumorsuk_UA
dc.typeArticleuk_UA

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Наукові праці. Кафедра дитячої хірургічної стоматології