Microscopic Polyangiitis is a “Masquerade Ball” in Modern Realities: A Literature Review
Ескіз недоступний
Дата
2023-12-28
Назва журналу
Номер ISSN
Назва тому
Видавець
Open Access Journal of Urology & Nephrology
Анотація
Microscopic polyangiitis (MPA) is an important new medical problem, as it shows increasing incidence and prevalence in the
population, especially after the outbreak of coronavirus disease 2019 (COVID-19). MPA is a multisystemic destructive disease
with a wide spectrum of heterogeneous clinical manifestations depending on the affected organs. The polymorphism of
nonspecific clinical signs and the variability of the clinical picture, which differs from patient to patient, can cause a diagnostic
delay and establish the correct diagnosis only in the late stages of the disease. That is why many patients consult and receive
treatment from different doctors before verifying the diagnosis.
In the review article, an analysis of literary sources was made, which highlighted classic renal and/or pulmonary symptoms,
skin, gastrointestinal, neurological and cardiovascular manifestations of MPA. It is important to note that the clinical
manifestations of MPA can be very different from the usual recognized patterns and manifest as unusual manifestations of
the disease with a hidden or atypical course, and therefore received the figurative name “the Great Masquerades”. So MPA can
often hide under the “mask” of other diseases, including COVID-19 itself, which significantly complicates its early diagnosis
and treatment. That is why doctors should be better informed about the different variants of the clinical course of MPA and
approaches to diagnosis, which will help eliminate delays in diagnosis. After all, the rapid diagnosis of MPA is important for
the initiation of adequate immunosuppressive therapy, which can both save lives, preserve organs from damage, and improve
the quality of life.
Опис
Ключові слова
ANCA-Associated Vasculitis, new Coronavirus infection SARS-Cov-2, COVID-19, clinical masks, clinical Picture, polyangiitis, microscopic
Бібліографічний опис
Microscopic Polyangiitis is a “Masquerade Ball” in Modern Realities: A Literature Review / T. I. Yarmola, O. O. Gutsalenko, L. A. Tkachenko, I. P. Katerenchuk, U. A. Kostrikova, H. L. Pustovoyt, V. V. Talash, I. V. Tsyganenko // J Urol Nephrol. – 2023. – Vol. 8, issue 4. – P. 000248.