Clinical predication of arterial hypotension in premature infants with early onset bacterial infections

Abstract

Abstract. The aim of our study was to substantiate the diagnostic criteria for the syndrome of arterial hypotension (AH) and indications for the appointment of hemodynamic support in premature infants with early onset bacterial infections. A prospective cohort study was conducted. 2 experimental groups were formed –premature babies with early onset bacterial infections and AH (n = 58), and control group (n = 62), premature babies without AH. Prognostic model, which included SILV (stroke index of left ventricle), blood pH and blood glucose, had high prognostic characteristics and the largest area under the ROC curve. The following diagnostic criteria can be used for the appointment of medical support for hemodynamics: the digital value of the level of mean blood pressure, expressed in mmHg, is less than the gestational age in weeks, and at least one of the following indicators –pH is less than 7.2, blood glucose level is less than 2.8 mmol/l, SILV is less than the normal ranges.