The dynamics of rat ileum mucosa hemomicrocirculatory stream parameters in transplantation of cryopreserved placenta concomitant with acute aseptic peritoneal inflammation

Abstract

The experimental study has been carried out on the ileum extracted from 140 senior male rats. Histological and histochemical methods of study have been applied. The response of all sections of hemomicrocirculatory stream has been detected in transplantations of cryopreserved lacenta, expressed in the enlargement of its mean diameter with maximal parameters on day 5 of the experiment. Simulation of the acute aseptic peritoneal inflammation at first led to narrowing of arterioles by 5% and capillaries by 2.3% on day 2-3 of the experiment, followed by the enlargement of their diameters on day 14 of the experiment. During the experiment the venule section enlarged in the diameter on day 14 of the experiment. In transplantation of cryopreserved placenta concomitant with acute aseptic peritoneal inflammation the arterioles and capillaries at first significantly reduced in diameter by 4% and 2%, respectively, on day 2, and then enlarged in the diameter on day 3-10. During the experiment the venule section enlarged significantly in the diameter on day 14 of the experiment. In administration of cryopreserved placenta concomitant with acute aseptic peritoneal inflammation the time period of its realization is shortened by 4-5 days.