A current management strategy for children with chronic viral hepatitis B, based on international and national guidelines

dc.contributor.authorNesina, I. M.
dc.contributor.authorKryuchko, T. O.
dc.contributor.authorPoda, O. A.
dc.contributor.authorTkachenko, O. Ya.
dc.contributor.authorKuzmenko, N. V.
dc.contributor.authorBubyr, L. M.
dc.contributor.authorНесіна, Інна Миколаївна
dc.contributor.authorКрючко, Тетяна Олександрівна
dc.contributor.authorПода, Ольга Анатоліївна
dc.contributor.authorТкаченко, Ольга Ярославівна
dc.contributor.authorКузьменко, Наталія Валентинівна
dc.contributor.authorБубир, Людмила Миколаївна
dc.date.accessioned2023-10-06T10:53:30Z
dc.date.available2023-10-06T10:53:30Z
dc.date.issued2023
dc.description.abstractPeculiarities of the course of chronic viral hepatitis B in children cause an important medical and social problem of health care, despite the implementation of modern treatment and prevention protocols. Pathogenetic mechanisms of the development and progression of viral hepatitis B infection, the presence of occult poorly diagnosed form, the impossibility of completely eliminating the virus and the specificity of the immune response in children are still not fully solved scientific problems. Material and Methods. The aim of this review is to examine current strategies for the diagnosis and treatment of chronic hepatitis B in children, based on international and national guidelines.Results. A detailed analysis of modern guidelines on the course and pathogenesis of viral hepatitis B infection confirms the fact that chronic hepatitis B is characterised by a complex interaction between the immune system of the virus and the patient, whose dynamic balance is not only responsible for the various phases of chronic viral hepatitis B infection but also leads to the result of antiviral treatment.Conclusion. Despite the introduction of vaccination of children against hepatitis B, the level of viral hepatitis B vaccination of children in Ukraine remains insufficient, which leads to the further spread of the infection. Currently available antiviral drugs can provide functional treatment of viral hepatitis B infection in a limited number of patients, but today's Ukrainian realities have caused a change in approach to the treatment and monitoring of patients, which may negatively affect the implementation of the key goals of the World Health Organization Global Strategy on the prevention, diagnosis and treatment of viral hepatitis.uk_UA
dc.identifier.citationA current management strategy for children with chronic viral hepatitis B, based on international and national guidelines / I. M. Nesina, T. O. Kryuchko, O. A. Poda, O. Y. Tkachenko, N. V. Kuzmenko, L. M. Bubyr // Journal of mother and child. – 2023. – Vol. 27, № 1. – Р. 134–141.uk_UA
dc.identifier.doi10.34763/jmotherandchild.20232701.d-23-00006
dc.identifier.urihttps://repository.pdmu.edu.ua/handle/123456789/21848
dc.language.isoenuk_UA
dc.publisherВидавнича платформа Sciendo (De Gruyter Group)uk_UA
dc.subjectchildrenuk_UA
dc.subjecthepatitis B virusuk_UA
dc.subjectchronic hepatitis Buk_UA
dc.subjectdiagnosisuk_UA
dc.subjecttreatmentuk_UA
dc.subjectmanagementuk_UA
dc.subjectpreventionuk_UA
dc.subjectHBVuk_UA
dc.titleA current management strategy for children with chronic viral hepatitis B, based on international and national guidelinesuk_UA
dc.typeArticleuk_UA

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