Neurophysiological features of the nociceptive trigeminal pathway in abdominally obese migraineurs
dc.contributor.author | Nikiforova, O. S. | |
dc.contributor.author | Delva, M. Yu. | |
dc.contributor.author | Нікіфорова, Олена Сергіївна | |
dc.contributor.author | Дельва, Михайло Юрійович | |
dc.date.accessioned | 2020-10-26T12:13:57Z | |
dc.date.available | 2020-10-26T12:13:57Z | |
dc.date.issued | 2020-04 | |
dc.description.abstract | The aim of this study were to assess clinical (cutaneous allodynia) and neurophysiological (R2 nBR component) markers of the nociceptive trigeminal-cervical pathway sensitization in the abdominally obese patients with episodic (EM) and chronic migraine (CM). Materials and methods: It had been recorded nBR within interictal period in 79 migraineurs with EM and CM who had abdominal obesity (AO) and normal body weight (NBW). Results: Patients with EM and AO had significantly lower pain thresholds than patients with EM and NBW – 0,55 (0,34-0,63) μV vs 0,70 (0,59-1,03) μV. The mean latency of R2 nBR component was significantly decreased in patients who had EM and AO (36,59 (31,95-42,41) ms) compared to patients who had EM and NBW(46,75 (42,93-52,34) ms). It had been revealed significant increasing of the mean amplitude of the component R2 nBR in patients who had EM and AO (158 (115-197) μV) compared to patients who had EM and NBW (124 (76-144) μV). In patients who had CM and AO, it had been found direct positive correlation between the amplitude of R2 nBR and severity of cutaneous allodynia – τ=0,4 (p=0,03), as well as found negative correlation between the latency of R2 nBR and severity of cutaneous allodynia – τ=-0,44 (p=0,02) within the interictal period of migraine. Conclusions: Neurophysiological findings may indirectly indicate faster migraine chronification in patients with EM and AO. | uk_UA |
dc.identifier.citation | Nikiforova O. S. Neurophysiological features of the nociceptive trigeminal pathway in abdominally obese migraineurs / O. S. Nikiforova, M. Yu. Delva // Wiadomości Lekarskie. – 2020. – Vol. LXXIII, issue 4. – С. 674–678. | uk_UA |
dc.identifier.doi | 10.36740/WLek202004109 | |
dc.identifier.uri | https://repository.pdmu.edu.ua/handle/123456789/13790 | |
dc.language.iso | en | uk_UA |
dc.subject | nociceptive blink reflex | uk_UA |
dc.subject | trigeminal pathway | uk_UA |
dc.subject | chronic migraine | uk_UA |
dc.subject | episodic migraine | uk_UA |
dc.subject | abdominal obesity | uk_UA |
dc.title | Neurophysiological features of the nociceptive trigeminal pathway in abdominally obese migraineurs | uk_UA |
dc.type | Article | uk_UA |
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