2022
Постійне посилання на фонд
Переглянути
Перегляд 2022 за Автор "Bilash, S. M."
Зараз показуємо 1 - 7 з 7
Результатів на сторінці
Налаштування сортування
Документ Features of the influence of ubistesin on the state of pulp microcirculation and the quality of the anesthetic effect during mandibular anesthesia in adolescent children(Полтавський державний медичний університет, 2022) Avetikov, D. S.; Lokes, K. P.; Bilash, S. M.; Pronina, O. M.; Streblovkyi, D. V.; Аветіков, Давид Соломонович; Локес, Катерина Петрівна; Білаш, Сергій Михайлович; Проніна, Олена Миколаївна; Стебловський, Дмитро ВалерійовичCurrently, in modern children's dentistry, various local anesthetics and methods of anesthesia are actively used, which affect the characteristics of pulpal blood flow and pulpal anesthesia in human teeth. This study aims to study the effect of ubisthesin injection during mandibular anesthesia on the state of pulp microcirculation and the quality and prolongation of the anesthetic effect in the treatment of molars and premolars of the lower jaw. Thirty adolescents who underwent treatment of medium and deep caries under mandibular anesthesia took part in the study. The pulp reopletismography technique was used to determine the quality of the effect of ubistezin on the above parameters. The Pulptest-Pro device was used to assess tooth sensitivity and pulp anesthesia. The obtained data made it possible to establish the probable absence of significant changes in the microcirculation of the pulp and the prolonged effect of this medicine on pain sensations and pain syndrome. The duration of mandibular anesthesia was 81.40 min for molars and 83.50 min for premolars. The impact of ubisthesin on blocking the inferior alveolar and lingual nerves without creating a depot of anesthetic, without reducing the blood flow of the pulp of molars and premolars of the lower jaw with the delayed removal of the local anesthetic solution from the affected tissues was established.Документ Morphological and morphometric changes in capillaries of the hemomicrocirculatory channel of the gingival mucosa during long-term exposure to a complex of food additives(Полтавський державний медичний університет, 2022) Oleksienko, V. V.; Bilash, S. M.; Білаш, Сергій Михайлович; Олексієнко, Владислав ВіталійовичFood additives are an important element of the food industry in the 21st century, which not only improve the taste of products, but also increase their shelf life. At the same time, they have negative properties that manifest themselves after a long period of use. The purpose of the experiment was to identify the simultaneous effect of several food additives on the gums, their structure and the changes that occur in them. During the study, it was established that the effect of a complex of food additives (sodium glutamate, sodium nitrite, and Ponseau 4 R) on the vessels of the gums of rats causes a violation of hemodynamic conditions and irreversible violations of the blood supply to the gums. Morphological changes of the capillaries were observed throughout the experiment and are characterized by changes in the thickness of the walls and the diameter of the lumen, which leads to pathological changes in the structural gums and their blood supply. That’s a reason of these experiment. Understanding of mechanisms of influence of food additives will lead us to better treatment of different diseases and prevent of using such number of synthetic chemicals in food industry.Документ Problem aspects of students practical training in clinical anatomy and operative surgery at the undergraduate stage(Полтавський державний медичний університет, 2022) Bilash, S. M.; Koptev, M. M.; Pronina, O. M.; Pirog-Zakaznikova, A. V.; Oliinichenko, Ya. O.; Donchenko, S. V.; Білаш, Сергій Михайлович; Коптев, Михайло Миколайович; Проніна, Олена Миколаївна; Пирог-Заказникова, Ангеліна Валеріївна; Олійніченко, Ярина Олександрівна; Донченко, Світлана ВладиславівнаГоловною проблемою підготовки здобувачів освіти з клінічної анатомії і оперативної хірургії на сьогодні є тотальне скорочення годин, відведених для практичної аудиторної роботи. Внесення змін до освітніх програм із уведенням обов’язкової освітньої компоненти «Клінічна ана томія і оперативна хірургія» є нагальною потребою, що сприятиме не лише покращанню розуміння морфології людини, але дозволить створити міцну базу практично-орієнтованих знань для практичної роботи у хірургічній галузіДокумент Progress and problems of vaccination against coronavirus infection Covid-19(Полтавський державний медичний університет, 2022-09-16) Karatash, A. V.; Bilanova, L. P.; Bilash, S. M.; Pronina, O. M.; Bilash, V. P.; Hryn, K. V.; Hryn, V. G.; Oliinichenko, Ya. O.; Караташ, Андрій Вячеславович; Біланова, Лариса Павлівна; Білаш, Сергій Михайлович; Проніна, Олена Миколаївна; Білаш, Валентина Павлівна; Гринь, Катерина Вікторівна; Гринь, Володимир Григорович; Олійніченко, Ярина ОлександрівнаThis article is devoted to the main achievements and problems associated with vaccination against the COVID-19 coronavirus infection. This problem remains relevant as the coronavirus infection is a highly contagious disease that spreads widely worldwide. Vaccination is currently the most effective way to prevent the occurrence of a coronavirus infection or its severe consequences. The difficulty is that vaccination against COVID-19 is effective only when the antigenic structure of the circulating virus matches the antigens contained in the vaccine (or, in the case of RNA and DNA vaccines, the viral antigens programmed into the genetic code). However, the coronavirus is constantly changing its genetic structure, resulting in new strains that differ from circulating variants and have pandemic potential, against which existing vaccines may be ineffective. This study aimed to determine the main approaches to creating a vaccine's advantages and disadvantages of vaccination through bibliographic analysis. A literature search was conducted among published peer-reviewed articles, books, textbooks, and monographs. The obtained data were systematized and processed. Attention was paid to the main approaches to creating vaccines against COVID-19; the problems of immunological imprinting and antibody-dependent enhancement of infection were assessed. It was established that strategies based on the use of DNA and RNA vaccines to solve the problem of their low immunogenicity in humans are a real alternative for the future development of medicine in the prevention of infectious diseases.Документ Structural organization of rats adrenal glands in normal state(Полтавський державний медичний університет, 2022) Donchenko, S. V.; Bilash, S. M.; Донченко, Світлана Владиславівна; Білаш, Сергій МихайловичThe study of the morphology of the adrenal glands has been carried out for many years. In recent decades, the pathology of the adrenal glands has been increasingly common because the negative influence of exogenous and endogenous factors is increasing, leading to the glands' morphofunctional disorders. Adrenal glands are not only essential elements of the hypothalamic-pituitary-adrenal system but are also endocrine organs. The interest of representatives of experimental medicine and scientists in changes in the structures of the adrenal glands does not subside. Thanks to the improvement of computer diagnostic methods, the percentage of detection of hormonally active and inactive, benign and malignant neoplasms of the adrenal glands has increased. The most common endocrine disorders are hyperaldosteronism, adrenergic and estrogenic balance disorders. The number of cases of detection of tumors of various genesis of the adrenal glands with the help of computer tomography is increasing significantly. Diagnosing and treating adrenal gland diseases remains an urgent medical and social problem. Therefore, determining the morphology of the adrenal glands of rats in the control group will serve as controls for comparison in the experiment.Документ Use of health-preserving features of learning in the context of optimization and improvement of edagogical management in higher medical education(Полтавський державний медичний університет, 2022) Bilash, V. P.; Svintsytska, N. L.; Bilash, S. M.; Pronina, O. M.; Bilanov, O. S.; Oliinichenko, Ya. O.; Tkachenko, O. T.; Білаш, Валентина Павлівна; Свінцицька, Наталія Леонідівна; Білаш, Сергій Михайлович; Проніна, Олена Миколаївна; Біланов, Олег Сергійович; Олійніченко, Ярина Олександрівна; Ткаченко, О. Т.One of the essential issues of today is the problem of human health. Any modern society, any state, puts the issues of preserving health, psychological comfort, long-term working capacity, and reproduction of healthy offspring first. Taking care of one’s health, tempering, rational nutrition, absence of bad habits, the ability to be sociable, beneficial for loved ones, friends, and society – all this in a complex makes up each person’s lifestyle. Each person’s lifestyle will always be relevant, which is essential in ensuring health. However, only the person himself can improve the condition of his body. The structure of the way of life is defined in those relations of subordination and coordination in which there are different life activities. It is manifested in the share of time spent on them, in what types of life activities a person spends his free time on, and which kinds of it he prefers in situations where a choice is impossible. If the way of life does not contain creative types of life, then its level decreases. Health is a person’s qualitative characteristic and contributes to achieving many goals. The contradiction between the achievement of material well-being and the need to be healthy is resolved by improving the objective conditions of human life. The attitude towards a healthy lifestyle of student youth is determined by objective circumstances, including education and training. It manifests itself in actions and deeds concerning factors affecting physical and mental well-being. One primary means of preserving health, physical activity, and the optimal psychophysical state of student youth is leading a healthy lifestyle, which includes giving up bad habits, adequate physical training, physical self-education, nutrition culture, and observing a daily routine. Adherence to these components is essential for maintaining student youth’s health and is one of the key factors contributing to their successful studies in institutions of higher medical educationДокумент Вплив консервантів та азобарвників на органи шлунково-кишкового тракту(Полтавський державний медичний університет, 2022) Ячмінь, Анастасія Ігорівна; Єрошенко, Галина Анатоліївна; Білаш, Сергій Михайлович; Шевченко, Костянтин Васильович; Лисаченко, Ольга Дмитрівна; Ваценко, Анжела Володимирівна; Передерій, Ніна Олександрівна; Yachmin, A. I.; Yeroshenko, G. A.; Bilash, S. M.; Shevchenko, K. V.; Lisachenko, O. D.; Vatsenko, A. V.; Perederii, N. A.Нітрати, будучи типовими ксенобіотиками, залучаються мікрофлорою людини і тварин в метаболічні процеси, в ході яких відновлюються спочатку до нітриту, а потім до катіона амонію, через освіту ряду проміжних продуктів. Нітрати і нітрити (NOS) при хронічному надходженні в великих кількостях призводять до утворення метгемоглобіну, в результаті чого може розвинутися хронічна аліментарна нітратно-нітритна метгемоглобінемія. Таким чином, основним місцем утворення реактивних сполук є шлунково-кишковий тракт (ШКТ) – центральний орган певних аспектів хімічної біології і фізіології цих сполук. Ponceau 4R (E 124) (синоніми: Acid Red 18, New Coccine) – це сульфований моноазобарвник, що включає переважно тринатрієвий 2-гідрокси-1‐ (4-сульфонато-1-нафтилазо) нафталін-6,8-дисульфонат (хімічна формула C20H11N2Na3O10S3, номер CAS 2611‐82‐7, молекулярна маса 604,48). Ponceau 4R виготовляється шляхом з’єднання діазотованої нафтіонової кислоти з кислотою G (2-нафтол-6,8-дисульфонової кислоти) і перетворення продукту сполучення в тринатрієву сіль і випускається у вигляді водорозчинного червоного порошку або гранул.